Results 11 to 20 of about 530,516 (247)

Neutrophils contribute to elevated BAFF levels to modulate adaptive immunity in patients with primary immune thrombocytopenia by CD62P and PSGL1 interaction

open access: yesClinical & Translational Immunology, 2022
Objectives Immune thrombocytopenia (ITP) is an autoimmune disease characterised by impaired platelet production and increased platelet destruction. However, the involvement of neutrophils in ITP is yet to be explored.
Pengcheng Xu   +12 more
doaj   +1 more source

Characterization of Neutrophil Function in Human Cutaneous Leishmaniasis Caused by Leishmania braziliensis. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2016
Infection with different Leishmania spp. protozoa can lead to a variety of clinical syndromes associated in many cases with inflammatory responses in the skin.
Jacilara Conceição   +7 more
doaj   +1 more source

Neutrophils and Asthma

open access: yesDiagnostics, 2022
Although eosinophilic inflammation is characteristic of asthma pathogenesis, neutrophilic inflammation is also marked, and eosinophils and neutrophils can coexist in some cases. Based on the proportion of sputum cell differentiation, asthma is classified
Akira Yamasaki   +2 more
doaj   +1 more source

Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine

open access: yesCellular Physiology and Biochemistry, 2017
Background/Aims: Cystic fibrosis (CF) is dominated by chronic inflammation and infection of the lung resulting in lung destruction and early death of patients. The lungs of CF patients are characterized by a massive accumulation of neutrophils.
Katrin Anne Becker   +9 more
doaj   +1 more source

Olfactomedin 4 marks a subset of neutrophils in mice

open access: yesInnate Immunity, 2019
Neutrophils are the most abundant immune cell of the innate immune system and participate in essential immune functions. Heterogeneity within neutrophils has been documented, but it is difficult to distinguish if these are altered activation states of a ...
Matthew N Alder   +5 more
doaj   +1 more source

Innate immune response in bovine neutrophils stimulated with Mycoplasma bovis

open access: yesVeterinary Research, 2021
Mycoplasma bovis (M. bovis) is a significant worldwide pathogen of cattle. Neutrophils have an important role in the innate immune response during infection with M. bovis. However, even though neutrophils accumulate in M. bovis infection, the interaction
Satoshi Gondaira   +8 more
doaj   +1 more source

Trans-basement membrane migration of eosinophils induced by LPS-stimulated neutrophils from human peripheral blood in vitro

open access: yesERJ Open Research, 2015
In the airways of severe asthmatics, an increase of neutrophils and eosinophils is often observed despite high-dose corticosteroid therapy. We previously reported that interleukin-8-stimulated neutrophils induced trans-basement membrane migration (TBM ...
Fuyumi Nishihara   +7 more
doaj   +1 more source

Human CD79b+ neutrophils in the blood are associated with early-stage melanoma

open access: yesFrontiers in Immunology, 2023
PurposeDue to their abundance in the blood, low RNA content, and short lifespan, neutrophils have been classically considered to be one homogenous pool.
Melissa A. Meyer   +20 more
doaj   +1 more source

The regulatory roles of neutrophils in adaptive immunity

open access: yesCell Communication and Signaling, 2019
Neutrophils have long been considered as cells playing a crucial role in the immune defence against invading pathogens. Accumulating evidence strongly supported the direct and indirect regulatory effects of neutrophils on adaptive immunity.
Yang Li   +5 more
doaj   +1 more source

Granulocyte-Macrophage Colony-Stimulating Factor-Activated Neutrophils Express B7-H4 That Correlates with Gastric Cancer Progression and Poor Patient Survival

open access: yesJournal of Immunology Research, 2021
Neutrophils are prominent components of gastric cancer (GC) tumors and exhibit distinct phenotypes in GC environment. However, the phenotype, regulation, and clinical relevance of neutrophils in human GC are presently unknown. Here, immunohistochemistry,
Zhi-guo Shan   +8 more
doaj   +1 more source

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