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Clinical & Translational Immunology, 2022 Objectives Immune thrombocytopenia (ITP) is an autoimmune disease characterised by impaired platelet production and increased platelet destruction. However, the involvement of neutrophils in ITP is yet to be explored.
Pengcheng Xu +12 more
doaj +1 more source
Immunological Reviews, 2016 SummaryNeutrophils play an important role in cancer. This does not only relate to the well‐established prognostic value of the presence of neutrophils, either in the blood or in tumor tissue, in the context of cancer progression or for the monitoring of therapy, but also to their active role in the progression of cancer.
Treffers, Louise W +4 more
openaire +4 more sources
Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions [PDF]
, 2016 Immunologically, active visceral leishmaniasis (VL) is characterised by profound immunosuppression, severe systemic inflammatory responses and an impaired capacity to control parasite replication.
Adem, E +19 more
core +3 more sources
Prefixation of Neutrophils for Neutrophil Antibody Testing [PDF]
Laboratory Medicine, 2014 The granulocyte immunofluorescence test based on flow cytometry is still the most commonly used method for detecting antineutrophil antibodies. We questioned whether neutrophil prefixation is necessary for this test.Three pretreatment methods using paraformaldehyde were compared: unfixed, short-fixed (3 minutes 40 seconds), and long-fixed (10 minutes ...
Ye Jee Shim, Dong Il Won
openaire +3 more sources
Influence of sex steroids on the viability and CD11b, CD18 and CD47 expression of blood neutrophils from dairy cows in the last month of gestation [PDF]
, 2006 In the period around parturition, cows experience an increased susceptibility for the development of Escherichia coli mastitis. This increased susceptibility has been correlated with a decreased functionality of neutrophils.
Burvenich, Christian +4 more
core +4 more sources
Impaired neutrophil directional chemotactic accuracy in chronic periodontitis patients [PDF]
, 2015 Aim: To investigate the chemotactic accuracy of peripheral blood neutrophils from patients with chronic periodontitis compared with matched healthy controls, before and after non-surgical periodontal therapy.
Agarwal +72 more
core +2 more sources
The Role of Neutrophils and Neutrophil Elastase in Pneumococcal Pneumonia [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 Streptococcus pneumoniae, also known as pneumococcus, is a Gram-positive diplococcus and a major human pathogen. This bacterium is a leading cause of bacterial pneumonia, otitis media, meningitis, and septicemia, and is a major cause of morbidity and mortality worldwide. To date, studies onS.
Hisanori Domon +3 more
openaire +4 more sources
Gap-junctional coupling between neutrophils and endothelial cells [PDF]
, 2003 Communication between leukocytes and endothelial cells is crucial for inflammatory reactions. Paracrine cross-talk and outside-in signaling (via adhesion molecules) have been characterized as communication pathways to date.
Gloe, Torsten +3 more
core +1 more source
Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine
Cellular Physiology and Biochemistry, 2017 Background/Aims: Cystic fibrosis (CF) is dominated by chronic inflammation and infection of the lung resulting in lung destruction and early death of patients. The lungs of CF patients are characterized by a massive accumulation of neutrophils.
Katrin Anne Becker +9 more
doaj +1 more source
Regulation of neutrophil senescence by microRNAs [PDF]
, 2011 Neutrophils are rapidly recruited to sites of tissue injury or infection, where they protect against invading pathogens. Neutrophil functions are limited by a process of neutrophil senescence, which renders the cells unable to respond to chemoattractants,
A Bonauer +60 more
core +4 more sources