Resistance patterns selected by nevirapine vs. efavirenz in HIV-infected patients failing first-line antiretroviral treatment: a bayesian analysis. [PDF]
WHO recommends starting therapy with a non-nucleoside reverse transcriptase inhibitor (NNRTI) and two nucleoside reverse transcriptase inhibitors (NRTIs), i.e. nevirapine or efavirenz, with lamivudine or emtricitabine, plus zidovudine or tenofovir.
Nicole Ngo-Giang-Huong +12 more
doaj +1 more source
Nevirapine plasma concentrations are associated with virologic response and hepatotoxicity in Chinese patients with HIV infection. [PDF]
BACKGROUND: Limited information is available on the relationship between nevirapine plasma concentrations and virologic response or liver toxicity in Chinese patients with HIV infection.
Jia Wang +10 more
doaj +1 more source
Background: First-line dual NRTI + NNRTI-based ART has shown good virological effectiveness; however, toxicity is common and is often the most common reason for modification of first-line ART.
Sumit Arora +3 more
doaj +1 more source
Determination of nevirapine in the presence of cucurbit(7)uril with a gold electrode [PDF]
The electrochemical oxidation of nevirapine, an anti-HIV drug, at a gold electrode was studied by voltammetric techniques. Nevirapine showed a signal that interfered with a working electrode wave.
Ana E. Esteva +5 more
doaj +2 more sources
Sub-therapeutic nevirapine concentration during antiretroviral treatment initiation among children living with HIV: Implications for therapeutic drug monitoring. [PDF]
Nevirapine, a component of antiretroviral therapy (ART) in resource-limited settings, known for auto-induction of metabolism, is initiated at half therapeutic dose until day 14 ('lead-in period'), and subsequently escalated to full dose. However, studies
Bindu Parachalil Gopalan +6 more
doaj +1 more source
Background A high incidence of rash has been reported in HIV-1 patients who received the anti-retroviral drug nevirapine. In addition, several studies have suggested that polymorphisms of human leukocyte antigen (HLA) genes may play important roles in ...
Tunthanathip Preecha +7 more
doaj +1 more source
Nevirapine in HIV maintenance therapy – can “old drugs” survive in current HIV management?
AIMS OF THE STUDY Nevirapine has an exceptional record for long-term tolerability with few side effects in human immunodeficiency virus (HIV) combined antiretroviral therapy (cART). Owing to relatively frequent hypersensitivity reactions (HSR)
Julia Notter +3 more
doaj +1 more source
ObjectivesTo investigate the potential of nevirapine 200 mg once-daily regimen and evaluate the influence of patient characteristics on nevirapine concentrations.MethodsThis was a prospective, multicentre cohort study with 532 HIV-infected patients ...
Huijuan Kou +9 more
doaj +1 more source
Electrochemical studies of nevirapine, an anti-HIV drug, and its assay in tablets and biological samples [PDF]
The electrochemical oxidation of nevirapine, an anti-HIV drug, at a glassy carbon electrode has been studied by voltammetric techniques. Nevirapine showed one well defined irreversible oxidation peak with a potential of 0.749 V in phosphate buffer at pH ...
JALDAPPAGARI SEETHARAMAPPA +2 more
doaj +3 more sources

