Results 31 to 40 of about 32,351 (183)

Green HPLC quantification method of lamivudine, zidovudine and nevirapine with identification of related substances in tablets

Green Chemistry Letters and Reviews, 2022
A green HPLC method for lamivudine (3TC), zidovudine (AZT) and nevirapine (NVP) determination in fixed-dose combination tablets was developed using ethanol as both one of the mobile phases and the solvent for sample preparation. This method was validated
Ludivine Vieira-Sellaï, Mercedes Quintana, Ousmane Diop, Olivier Mercier, Sebastien Tarrit, Nawal Raimi, Alassan Ba, Benoit Maunit, Marie-Josephe Galmier   +8 more
doaj   +1 more source

Me-Better Drug Design Based on Nevirapine and Mechanism of Molecular Interactions with Y188C Mutant HIV-1 Reverse Transcriptase

Molecules, 2022
In this paper, the Y188C mutant HIV-1 reverse transcriptase (Y188CM-RT) target protein was constructed by homology modeling, and new ligands based on nevirapine (NVP) skeleton were designed by means of fragment growth. The binding activity of new ligands
Yan Wang, Aidong Wang, Jianhua Wang, Xiaoran Wu, Yijie Sun, Yan Wu   +5 more
doaj   +1 more source

Response to highly active antiretroviral therapy among severely immuno-compromised HIV-infected patients in Cambodia. [PDF]

, 2007
BACKGROUND: HAART efficacy was evaluated in a real-life setting in Phnom Penh (Médecins Sans Frontières programme) among severely immuno-compromised patients.
Akileswaran, Babiker, Badri, Braitstein, Calmy, Carr, Coetzee, Cozzi-Lepri, Dragsted, Egger, Ferradini, French, Furber, Hirsch, Ivers, Kaufmann, Keiser, Laurent, Lawn, Le Moing, Mahajan, Matthews, Mocroft, Pean, Ratnam, Severe, Shetty, Smit, Smith, Sungkanuparph, van Leth   +30 more
core   +3 more sources

Focus on chirality of HIV-​1 non-​nucleoside reverse transcriptase inhibitors [PDF]

, 2016
Chiral HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are of great interest since one enantiomer is often more potent than the corresponding counterpart against the HIV-1 wild type (WT) and the HIV-1 drug resistant mutant strains.
Famiglini, Valeria, Silvestri, Romano
core   +2 more sources

The peripartum viral load cascade and outcomes of infants exposed to HIV in Lesotho. [PDF]

HIV Med
Abstract Objectives This study describes the peripartum viral load (VL) monitoring cascade among individuals initiating antiretroviral therapy (ART) before delivery, as well as HIV testing, prophylaxis and outcomes of their infants in routine care in Lesotho, southern Africa.
Haenggi K, Mokebe M, Motaboli L, Chakela MG, Kao M, Kopo M, Ayakaka I, Nyakane M, Tarumbiswa T, Labhardt ND, Brown JA, Tschumi N.   +11 more
europepmc   +2 more sources

Implementing a tenofovir-based first-line regimen in rural Lesotho: clinical outcomes and toxicities after two years. [PDF]

, 2011
The latest World Health Organization guidelines recommend replacing stavudine with tenofovir or zidovudine in first-line antiretroviral therapy in resource-limited settings.
Birkus, Brinkman, Callaghan, Cohen, Davidson, Ford, Gallant, Gallant, Grim, Hawkins, Mills, Pozniak, Stone   +12 more
core   +2 more sources

Effectiveness and safety of two‐drug regimens containing an integrase inhibitor and reverse transcriptase inhibitor in a cohort of virologically suppressed people with HIV: Data from the COMBINE‐2 study

HIV Medicine, EarlyView.
Abstract Objectives This study assessed real‐world effectiveness and safety of switching to dual therapy regimens consisting of an integrase inhibitor (INSTI), and reverse transcriptase inhibitor (RTI), among suppressed people living with HIV in Europe.
Cristina Mussini, Cassidy Henegar, Lambert Assoumou, Stephane de Wit, Margaret Johnson, Eugenia Quiros‐Roldan, Chris Kenyon, Colin Deschanvres, David Zucman, Frank Post, Roya Movahedi, Laura Comi, Julie Fox, Geoffrey Liegeon, Charlotte Martin, Jonathan Edwards, Giorgio Tiecco, Marc Delforge, Leigh Ragone, Bryn Jones, Jean van Wyk, Michael Aboud, Carl Fletcher, Anton Pozniak, Vani Vannappagari   +24 more
wiley   +1 more source

Steady-state pharmacokinetics of Nevirapine in HIV-1 infected adults in India [PDF]

, 2007
Background and Objectives: A variety of demographic factors, sex, and degree of immunosuppression can influence antiretroviral drug concentratians. The authors studied the influence of immune status, sex, and body mass index (BMI) on the steady-state ...
A.K. Hemanthkumar, C. Padmapriyadarsini, G. Narendran, Geetha Ramachandran, Hosseinipour MC, Kappelhoff BS, La Porte C., Phair JP, S. Anitha, S. Rajasekaran, Soumya Swaminathan, Sudha Subramanyam, V. Kumaraswami, World Health Organization.   +13 more
core   +1 more source

Anti-Retroviral Treatment in dr. Sardjito Central General Hospital Yogyakarta

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology)
Background: Adverse cutaneous drug reactions (ACDRs) affect 2-3% of hospitalized patients globally, wherein approximately 2% (1 in 1,000 cases) accounted for a severe form of cutaneous drug reactions.
Labitta Pachira Aquaira, Sri Awalia Febriana, Nurwestu Rusetiyanti   +2 more
doaj   +1 more source

Affecting factors to effectiveness of starting therapy in children with hiv infection

Журнал инфектологии, 2015
The purpose of the research – to characterize of the factors that influence the effectiveness of the starting highly activе antiretroviral therapy in children with HIV infection.Materials and methods.
V. B. Denisenko, E. N. Simovanyan
doaj   +1 more source