Results 41 to 50 of about 32,351 (183)

The use of QbD for the development and validation of a stability-indicating RP-HPLC method for the quantitation of nevirapine in bulk, tablet and niosome formulations

open access: yesFrontiers in Analytical Science
IntroductionA reversed-phase high-performance liquid chromatographic (RP-HPLC) method was developed and validated for the quantitation of nevirapine (NVP) in bulk drug, commercial tablets, and niosome formulations using an Analytical Quality by Design ...
Bwalya A. Witika, Roderick B. Walker
doaj   +1 more source

New Crystal Forms for Biologically Active Compounds. Part 1: Noncovalent Interactions in Adducts of Nevirapine with XB Donors

open access: yesCrystals, 2019
Stabilization of specific crystal polymorphs of an active pharmaceutical ingredient is crucial for preventing uncontrollable interconversion of various crystalline forms, which affects physicochemical properties as well as physiological activity.
Mariya A. Kryukova   +4 more
doaj   +1 more source

Genotype–Specific Safety and Pharmacokinetics of Cannabidiol in Healthy Volunteers

open access: yesClinical and Translational Science, Volume 19, Issue 1, January 2026.
ABSTRACT Cannabidiol (CBD) use has increased in America due to its widespread availability. Cannabidiol is metabolized by multiple polymorphic enzymes including CYP3A, CYP2C9, and CYP2C19. We sought to evaluate the genotype‐specific adverse events and pharmacokinetic profiles of cannabidiol, 7‐OH cannabidiol (an active metabolite), and 7‐COOH ...
Jumar Etkins   +11 more
wiley   +1 more source

Adherence to antiretroviral therapy assessed by drug level monitoring and self-report in cameroon [PDF]

open access: yes, 2008
OBJECTIVES: To compare adherence to antiretroviral therapy using drug level monitoring and self-report and to explore the relation between these 2 methods and viral load measurements.
Alexandra Calmy   +29 more
core   +3 more sources

IMPROVING ANTIRETROVIRAL THERAPY IN CHILDREN WITH HIV INFECTION

open access: yesДетские инфекции (Москва), 2018
The objective — to characterize the effectiveness of different schemes of antiretroviral therapy in children with HIV infection and on the basis of the obtained data to improve of the disease treatment.Patients and Methods: A clinical, immunological and ...
V. B. Denisenko, E. N. Simovanyan
doaj   +1 more source

Major revision version 13.0 of the European AIDS Clinical Society guidelines 2025

open access: yesHIV Medicine, Volume 27, Issue 1, Page 18-32, January 2026.
Abstract Background The European AIDS Clinical Society (EACS) guidelines were revised for the 21st time in 2025, with updates covering all aspects of HIV care. Key Points of the Guidelines Update The structure of the guidelines has been reorganized into two parts: Part I focuses on the management and prevention of HIV and related infections, and Part ...
Juan Ambrosioni   +19 more
wiley   +1 more source

Pharmacological and clinical evidence of nevirapine immediate- and extended-release formulations

open access: yesHIV/AIDS: Research and Palliative Care, 2012
Javier Ena, Concepción Amador, Conxa Benito, Francisco PasquauHIV Unit, Hospital Marina Baixa, Villajoyosa, SpainAbstract: We reviewed the current information available on nevirapine immediate- and extended-release formulations and its role in
Ena J, Amador C, Benito C, Pasquau F
doaj  

Delay of cell growth and loss of stemness by inhibition of reverse transcription in human mesenchymal stem cells derived from dental tissue

open access: yesAnimal Cells and Systems, 2019
The present study investigated the cellular properties in the dental tissue-derived mesenchymal stem cells (DSCs) exposed to nevirapine (NVP), an inhibitor of reverse transcriptase (RTase).
Won-Cheol Lee   +8 more
doaj   +1 more source

EBV+ and Kaposi’s Sarcoma Herpesvirus‐Associated Multicentric Castleman Disease in a Patient With HIV Infection: A Case Report

open access: yesCase Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.
Multicentric Castleman disease is a rare proliferative disease of lymphoid tissue. It has rarely been reported in Asian countries, particularly in HIV‐positive patients. Here, we report a case of Kaposi’s sarcoma herpesvirus‐associated Multicentric Castleman disease (KSHV‐MCD).
Mai-Yin Huang   +6 more
wiley   +1 more source

Weight gain at 3 months of antiretroviral therapy is strongly associated with survival: evidence from two developing countries [PDF]

open access: yes, 2009
BACKGROUND: In developing countries, access to laboratory tests remains limited, and the use of simple tools such as weight to monitor HIV-infected patients treated with antiretroviral therapy should be evaluated.
Arnaud Fontanet   +33 more
core   +3 more sources

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