Results 71 to 80 of about 26,994,982 (307)
Teaching methodologies in civil engineering: a multidisciplinary approach [PDF]
, 2018 Nowadays universities are rethinking their teaching methodologies not only in order to adapt to the use of new technologies, such as the ICT (information and communication technologies) or the GIS (Geographic Information Systems) but also in order to ...
Santos, Bertha +3 more
core
Methods Investigating Food-Related Behaviour
, 2020 Food-related behaviours are complicated actions governed by a mix of cultural conventions, social interactions, individual perceptions and psychological influences.
Dean, M, Raats, MM, Lähteenmäki, L
core +1 more source
New approach methodologies to assess wanted and unwanted drugs-induced immunostimulation
Current Research in ToxicologyThis review examines various classes of drugs, focusing on their therapeutic and adverse effects, particularly in relation to immunostimulation. We emphasize the potential of new approach methodologies (NAMs) to study both expected and unexpected ...
Valeria Bettinsoli +5 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
New approach methodologies for risk assessment using deep learning
EFSA JournalThe advancement of technologies and the development of more efficient artificial intelligence (AI) enable the processing of large amounts of data in a very short time.
Enol Junquera +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Creating training opportunities in new approach methodologies for early-career researchers
NAM JournalAs research and testing methods rapidly advance, there is a pressing need to train the next generation of scientists in new approach methodologies (NAMs)—human-specific, nonanimal methods—to reduce animal use, improve clinical translation, and solve ...
Janine McCarthy +5 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
New Approach Methodologies: Physiological Responses of Daphnids to Pharmaceutical Mixtures
ProceedingsThe levels of pharmaceuticals have been continuously increasing in aquatic ecosystems over the past decade due to their extensive use in human and veterinary medicine.
Emma Rowan +3 more
doaj +3 more sources
NAM JournalThe gradual rate of phasing out animal use in regulatory testing has been attracting greater attention from policy makers, the scientific community, and industry.
Aleksandra Čavoški +2 more
doaj +1 more source