Results 111 to 120 of about 54,991 (287)

Recreational Drug Use at a Music Festival: A Dual Approach Using Hair Biomarkers Analysis and Participant Self‐Reported Drug Use

Drug Testing and Analysis, EarlyView.
Combined self‐report and hair analysis in festival attendees (n = 249) revealed substantial discrepancies in drug use reporting, particularly for stimulants and dissociatives. This integrated approach enhances detection of poly‐drug use and provides a more reliable basis for monitoring and harm‐reduction strategies.
A. Y. Simão, T. Rosado, M. Barroso, M. Andraus, E. Gallardo   +4 more
wiley   +1 more source

The impact of lifetime substance use on psychiatric comorbidities and treatment seeking in patients with alcohol use disorders

Scientific Reports
It is well-recognized that individuals with alcohol-related disorders often use other psychoactive substances; however, systematic research on this topic remains limited.
Piotr Engelgardt, Maciej Krzyżanowski, Małgorzata Borkowska-Sztachańska, Agnieszka Wasilewska, Michał Ciucias   +4 more
doaj   +1 more source

Segmental Hair Analysis of Diphenhydramine and Cyclizine Following a Single Dose

Drug Testing and Analysis, EarlyView.
A single oral dose of diphenhydramine and cyclizine can be quantified in human head hair for a minimum of 5 months and, in certain cases, for up to 1 year following intake. Among 12 study participants, the measured concentrations ranged from 0 to 610 pg/mg within 1 year post‐intake.
Jan Bílek, Marie Katrine Klose Nielsen, Robert Kronstrand, Sys Stybe Johansen   +3 more
wiley   +1 more source

Neuropharmacological characterization of the new psychoactive substance methoxetamine

Neuropharmacology, 2017
The use of new psychoactive substances (NPS) is steadily increasing. One commonly used NPS is methoxetamine (MXE), a ketamine analogue. Several adverse effects have been reported following MXE exposure, while only limited data are available on its neuropharmacological modes of action. We investigated the effects of MXE and ketamine on several endpoints
Hondebrink, Laura, Kasteel, Emma E J, Tukker, Anke M, Wijnolts, Fiona M J, Verboven, Anouk H A, Westerink, Remco H S   +5 more
openaire   +4 more sources

Determination of THC and THC‐COOH in Dried Capillary Blood Spots and Comparison to Venous Blood of Recreational Cannabis Consumers in a Pilot Study

Drug Testing and Analysis, EarlyView.
A new extraction method was developed and validated for the extraction of THC and THC‐COOH from capillary blood samples collected as dried blood spots. The extracts were analysed using HPLC–MS/MS resulting in high extraction efficiencies for both THC and THC‐COOH.
Matthias Bantle, Willi Schirmer, Joel Bruegger, Thomas Wüthrich, Andreas Längin, Lena Zwicker, Reto Auer, Wolfgang Weinmann   +7 more
wiley   +1 more source

The 'new psychoactive substances'

, 2020
One of the worst revolutions in illicit drug misuse took place with the development of synthetic drugs. These are drugs that are created using man-made chemicals rather than natural ingredients. Such drugs are not a new phenomenon and have been around since the 1960s when d-lysergic acid (LSD) became popular. This was followed by the growing popularity
openaire   +1 more source

Associations Between Severe Food Insecurity and Food Addiction in Brazilian Low‐Income Women

European Eating Disorders Review, EarlyView.
ABSTRACT Objective The present study aims to assess the distribution of food addiction (FA) across different levels of food insecurity (FI) in Brazilian women of reproductive age living in poverty, and to investigate the association between FA and FI. Method This is a cross‐sectional study conducted between October 2020 and May 2021 in 40 urban favelas
Amanda Ribeiro Berta, Luiz Gonzaga Ribeiro Silva‐Neto, Juliana Souza Oliveira, Nassib Bezerra Bueno, Telma Maria de Menezes Toledo Florêncio, Ana Paula Grotti Clemente, Giovana Longo‐Silva, Risia Cristina Egito de Menezes   +7 more
wiley   +1 more source

New Psychoactive Substance Consumption Within the UK Homeless Population

Emerging Trends in Drugs, Addictions, and Health
Introduction: The last few years have seen the emergence of new psychoactive substance among the homeless population, specifically synthetic cannabinoid receptor agonists.
T. Coombs, T. Ginige, P. Van Calster, A. Abdelkader, O. Corazza, S. Assi   +5 more
doaj   +1 more source

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

Mapping persistence and change in psychological problems during the transition to adolescence: Adding, subtracting, shifting, and persisting

JCPP Advances, EarlyView.
Pathways from a psychological problem at baseline to a different problem at follow‐up that are conflated in traditional 2 × 2 calculations of heterotypic change (left panel), but parsed in 4 × 4 analyses (right panel). Note that the same children who are in the shaded cells in the 2 × 2 tables in the left panel are in the shaded cells in the pairwise 4 
Brooks Applegate, Benjamin B. Lahey
wiley   +1 more source