Results 161 to 170 of about 34,567,041 (234)

Resolving three GABA induced electrogenic events and GABA‐coupling stoichiometry for Na+ and Cl− in hGAT‐1

open access: yesThe FEBS Journal, EarlyView.
Using solid‐supported membrane electrophysiology, we resolved three electrogenic events during GABA transport by the human GAT‐1 transporter. A rapid occlusion step (E1) is followed by a GABA‐induced Na+ leak current (E2), which becomes prominent under steep Na+ gradients, and a slower current associated with Na+‐coupled GABA transport (E3 ...
Rocco Zerlotti   +8 more
wiley   +1 more source

Fatigue Life Evaluation Using the Damage‐Equivalent Strain for 7075‐T6 Aluminum Alloy Under Bending and Torsion Bending Vibrations

open access: yesFatigue &Fracture of Engineering Materials &Structures, EarlyView.
ABSTRACT The vibrations caused by external factors (such as fluids) or internal factors often pose strength‐related problems in mechanical and structural components. Although several studies have investigated the material fatigue characteristics during vibration, reports on complex vibration modes such as torsion bending are limited.
Junji Sakamoto   +2 more
wiley   +1 more source

Lignan‐rich Norway spruce (Picea abies) resin extract exhibits anti‐inflammatory, skin‐regenerative and anti‐acne effects: In vitro, in silico, biocompatibility and exploratory clinical findings

open access: yesInternational Journal of Cosmetic Science, EarlyView.
GA text A 30% Picea abies resin extract cream combined antimicrobial, anti‐inflammatory and early pro‐repair activities relevant to acne‐prone skin. The formulation showed strong activity against Cutibacterium acnes, reduced inflammatory cytokines and demonstrated promising tolerability and efficacy in an exploratory in‐use study. Abstract Objective To
Simone Parrotta   +4 more
wiley   +1 more source

Role of NF-E2 related factor 2 (Nrf2) on chemotherapy resistance in acute myeloid leukemia (AML) and the effect of pharmacological inhibition of Nrf2. [PDF]

open access: yesPLoS One, 2017
Karathedath S   +8 more
europepmc   +1 more source

Genetic Susceptibility to Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger   +5 more
wiley   +1 more source

Sirtuin 1 Promotes Hyperoxia-Induced Lung Epithelial Cell Death Independent of NF-E2-Related Factor 2 Activation. [PDF]

open access: yesAm J Respir Cell Mol Biol, 2016
Potteti HR   +5 more
europepmc   +1 more source

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