Results 251 to 260 of about 12,632,659 (295)

Activate NF-kappa B or die?

Current biology : CB, 1997
Activation of the transcription factor NF-kappaB has been linked to apoptosis, with the factor playing either an anti-apoptotic or a pro-apoptotic role, depending on the type of cell in which it is expressed.
V R, Baichwal, P A, Baeuerle
openaire   +1 more source

NF-kappa B signaling and carcinogenesis.

Current pharmaceutical design, 2007
NF-kappaB is an inducible transcription factor that is controlled by the signal activation cascades. NF-kappaB controls a number of genes involved in immuno-inflammatory responses, cell cycle progression, inhibition of apoptosis and cell adhesion, thus promoting carcinogenesis and cancer progression.
Takashi, Okamoto, Takaomi, Sanda, Kaori, Asamitsu   +2 more
openaire   +1 more source

NF-kappa B comes home.

Immunity, 2005
NF-kappa B was discovered because of its binding to the Ig kappa locus intronic enhancer, but deletion of its binding site does not appear to affect V-to-J kappa rearrangement. New work by Verkoczy et al. in this issue of Immunity suggests that NF-kappa B regulates Ig kappa rearrangement after all, by activating RAG expression during receptor editing.
Rupesh H, Amin, Mark S, Schlissel
openaire   +1 more source

[NF-kappa B and prostatic adenocarcinoma].

Zhonghua nan ke xue = National journal of andrology, 2007
Nuclear factor of kappa B (NF-kappa B) is a multipolar nuclear transcription factor, and adjusts many gene expressions concerned with immunization, apoptosis, inflammation, neoplasia and metastasis. Recently, NF-kappa B has become a kind of hot spot in the studies of neoplasia, infiltration, metastasis and drug resistance.
Song-Tao, Xiang, Hui, Guo, Si-Wei, Zhou
openaire   +1 more source

Tuning NF-kappa B activity

Biochimica et biophysica acta-Molecular basis of disease, 2013
NF-kappa B is an important regulator of immunity and inflammation, and its activation pathway has been studied extensively. The mechanisms that downregulate the activity of NF-kappa B have also received a lot of attention, particularly since its activity needs to be terminated to prevent chronic inflammation and subsequent tissue damage.
Bartuzi, Paulina, Hofker, Marten H., van de Sluis, Bart   +2 more
openaire   +1 more source

The NF-kappa B p65 promoter.

Journal of acquired immune deficiency syndromes, 1993
The promoter of the human gene encoding the p65 subunit of the transcription factor NF-kappa B was cloned and the nucleotide sequence determined. The p65 promoter lacks both TATA and CCAAT consensus sequences. The p65 promoter contains three consensus binding sites of the transcription factor SP1.
K, Ueberla, Y, Lu, E, Chung, W A, Haseltine   +3 more
openaire   +1 more source

NF-kappa B precursor p100 inhibits nuclear translocation and DNA binding of NF-kappa B/rel-factors.

Oncogene, 1993
The NF-kappa B precursor p100 (lyt-10, p97, p98) generates after proteolytic processing a 52 kDa subunit, which can bind to kappa B-motifs. A deregulated form of the p100 gene, which is structurally altered by a t(10;14) translocation, has a potential oncogenic role in certain human B cell lymphomas.
M, Naumann, A, Nieters, E N, Hatada, C, Scheidereit   +3 more
openaire   +1 more source

Explaining the unsuitability of the kappa coefficient in the assessment and comparison of the accuracy of thematic maps obtained by image classification

Remote Sensing of Environment, 2020
Giles Foody
exaly  

Large-Sample Variance of Fleiss Generalized Kappa

Educational and Psychological Measurement, 2021
Kilem Gwet
exaly  

The Kappa Statistic in Reliability Studies: Use, Interpretation, and Sample Size Requirements

Physical Therapy, 2005
Julius Sim
exaly