Results 91 to 100 of about 99,051 (206)
Advanced Science, Volume 13, Issue 10, 18 February 2026.Netrin‐1 expression is upregulated in hepatic stellate cells (HSCs) during metabolic dysfunction–associated steatohepatitis and injury‐mediated liver fibrosis. Secreted Netrin‐1 establishes an autocrine positive feedback loop by binding to UNC5B receptors on HSCs.
Jiahui Zhao +8 more
wiley +1 more source
Human Bocavirus NS1 and NS1-70 Proteins Inhibit TNF-α-Mediated Activation of NF-κB by targeting p65. [PDF]
, 2016 Human bocavirus (HBoV), a parvovirus, is a single-stranded DNA etiologic agent causing lower respiratory tract infections in young children worldwide.
A Christensen +40 more
core +1 more source
Biochemical pharmacology, 2006 Cancer is a multistep process during which cells acquire genetic alterations that drive the progressive transformation of normal cells into highly malignant cells. Self-sufficiency in growth, insensitivity to anti-growth signals, evasion of apoptosis, limitless replicative potential, sustained angiogenesis, tissue invasion and metastasis, are ...
Pacifico F, Leonardi A
openaire +2 more sources
Clinical Case Reports, Volume 14, Issue 2, February 2026.Exocrine Pancreatic Insufficiency Manifesting Before Insulin Dependence in Adult‐Onset Type 1 Diabetes. Unexplained steatorrhea or weight loss in people with diabetes warrants further investigations including imaging of abdomen/pancreas, exocrine pancreatic function and diabetes antibody testing.
Panagiotis Pavlou +2 more
wiley +1 more source
Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways. [PDF]
, 2012 The NF-κB protein RelB controls dendritic cell (DC) maturation and may be targeted therapeutically to manipulate T cell responses in disease. Here we report that RelB promoted DC activation not as the expected RelB-p52 effector of the noncanonical NF-κB ...
Asagiri, Masataka +10 more
core +2 more sources
Cancer Reports, Volume 9, Issue 2, February 2026.ABSTRACT Background Colon adenocarcinoma (COAD), although the third‐most common type of gastrointestinal tumors, still lacks specific biomarkers for early diagnosis, treatment, and prognosis. Aims This study aimed to evaluate the CD276 in tumorigenesis, prognosis and immunity for colon adenocarcinoma.
Rui Chen +4 more
wiley +1 more source
Molecular networks discriminating mouse bladder responses to intravesical bacillus Calmette-Guerin (BCG), LPS, and TNF-α [PDF]
, 2008 Background Despite being a mainstay for treating superficial bladder carcinoma and a promising agent for interstitial cystitis, the precise mechanism of Bacillus Calmette-Guerin (BCG) remains poorly understood.
Dozmorov Igor +7 more
core +2 more sources
The role of NF-kappaB in endometriosis
Frontiers in Bioscience, 2012 The nuclear factor kappaB (NF-kappaB) is a ubiquitously expressed transcription factor playing vital roles in innate immunity and other processes involving cellular survival, proliferation, and differentiation. This review highlights the importance of NF-kappaB in the pathophysiology of endometriosis. Constitutive activation of NF-kappaB has been shown
Apostolos, Kaponis +7 more
openaire +2 more sources
Identification of non-canonical NF-κB signaling as a critical mediator of Smac mimetic-stimulated migration and invasion of glioblastoma cells [PDF]
, 2013 As inhibitor of apoptosis (IAP) proteins can regulate additional signaling pathways beyond apoptosis, we investigated the effect of the second mitochondrial activator of caspases (Smac) mimetic BV6, which antagonizes IAP proteins, on non-apoptotic ...
Eckhardt, Ines +4 more
core +3 more sources
TNF Superfamily: A Growing Saga of Kidney Injury Modulators
Mediators of Inflammation, 2010 Members of the TNF superfamily participate in kidney disease. Tumor necrosis factor (TNF) and Fas ligand regulate renal cell survival and inflammation, and therapeutic targeting improves the outcome of experimental renal injury.
Maria D. Sanchez-Niño +11 more
doaj +1 more source