Results 31 to 40 of about 15,571 (214)
Molecular Genetics & Genomic Medicine, 2020 Background It is well known that nuclear factor of activated T cells c1 (NFATc1) expression is closely associated with progression of many cancers. And we found that miR‐338 could directly target the NFATc1.
Wei He, Jibin Lu
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NFATc1 activates the acetylcholinesterase promoter in rat muscle [PDF]
Journal of Neurochemistry, 2004 AbstractNuclear factor of activated T‐cells (NFAT) plays a role in the response of muscle to chronic contractile activity that can result in fiber type switching and hypertrophy. These effects are due in part to activation of target genes following Ca2+‐mediated nuclear translocation of NFAT.
Tatiana V, Cohen, William R, Randall
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Cell Communication and Signaling, 2019 Background Progression of prostate cancer from benign local tumors to metastatic carcinomas is a multistep process. Here we have investigated the signaling pathways that support migration and invasion of prostate cancer cells, focusing on the role of the
Sini K. Eerola +13 more
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Do we use methylation of NFATC1 and FOS genes as a biomarker for postmenopausal osteoporosis?
Balkan Journal of Medical Genetics, 2021 Genetic and epigenetic factors have an important role during the development of osteoporosis. Receptor activator of nuclear factor-κ B (NF-κB) (RANK)/receptor activator of NF-κB ligand (RANKL) pathway is important for the bone remodeling, and NFATC1 and ...
Kalkan R, Tosun O
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NFATc1 mutants abolished the effects of DYRK1A. [PDF]
, 2017 A. Nine mutant constructs of NFATc1 were co-transfected with pCMV-DYRK1A in HEK293 cells. B. HEK293 cells co-transfected with NFATc1 and nine mutant constructs of NFATc1 were treated with proteasome inhibitor lactacystin (5uM) for 24 hours after ...
Yuankai Zhang (3779878) +6 more
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Vitamin Regulation of Osteoclast Differentiation
Central Asian Journal of Medical Sciences, 2020 Objectives: Vitamins play critical roles in cellular metabolism, growth, and many enzymatic processes of the human body. They are also crucial in signal transduction and transcription pathways of many processes, including osteoclast differentiation. This
Erdenezaya Odkhuu +5 more
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Cells, 2022 Hematopoietic stem and progenitor cell (HSPC) maintenance and the differentiation of various lineages is a highly complex but precisely regulated process.
Carlotta Barahona de Brito +3 more
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Activated NFATc1 negatively modulates Sp1 nuclear content. [PDF]
, 2013 (A) HK-2 cells were untreated (c) or treated with CsA 10nM, NGF 100ng/ml alone or in combination for 15h before lysis. Nuclear and cytosolic expression of NFATc1 (Antibody dilution 1:100) and Sp1 (1:1000) were evaluated.
Donatella Vizza (480988) +8 more
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eLife, 2015 Osteoclasts are bone-resorbing cells essential for skeletal remodeling. However, over-active osteoclasts can cause bone-degenerative disorders. Therefore, the level of NFATc1, the master transcription factor of osteoclast, must be tightly controlled ...
Xiaoxiao Li +5 more
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Effect of estradiol and NFATc1-specific siRNA on NFATc1 and MUC5AC mRNA expression in 1HAE0 cells. [PDF]
, 2014 A) Quantitative real-time PCR demonstrates 10−7 M estradiol stimulates a time-dependent increase in NFATc1 mRNA/HPRT1 expression with maximal increase at 4 h.
Shu-Fan Paul Man (588858) +4 more
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