Results 281 to 290 of about 108,193 (313)
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Tracking TrkA’s Trafficking: NGF Receptor Trafficking Controls NGF Receptor Signaling
Molecular Neurobiology, 2007Growth factors such as the neurotrophins promote neuronal survival and shape neuronal morphology. Neurotrophin receptors are located on the surface of axons and dendrites and must convey their signal retrogradely to the nucleus to influence transcription of target genes. The distance between the site of receptor activation and the nucleus is tremendous.
T, Moises +8 more
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ATP–NGF-complex, but not NGF, is the neuroprotective ligand
Neurochemistry International, 2011We have shown previously that nerve growth factor (NGF) requires only low nanomolar ATP concentrations in the cell culture medium to protect cortical rat neurons (CRN) from cellular damage induced by staurosporine (STS). We have also demonstrated before that NGF and other growth factors form stable non-covalent complexes with ATP.
Katja Bettina, Ferenz +3 more
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Psychoneuroendocrinology, 2006
It was July 1983 when, following an almost 10-yearlong discussion with Rita Levi–Montalcini about the physiological role of NGF stored in the submaxillary glands of adult male mice, in collaboration with Luigi Aloe, we decided to attempt a crucial experiment.
Enrico, Alleva, Igor, Branchi
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It was July 1983 when, following an almost 10-yearlong discussion with Rita Levi–Montalcini about the physiological role of NGF stored in the submaxillary glands of adult male mice, in collaboration with Luigi Aloe, we decided to attempt a crucial experiment.
Enrico, Alleva, Igor, Branchi
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Brain Research, 2004
Nerve growth factor (NGF) is an important factor regulating survival in development and during regenerative or neuroinflammatory processes. The aim of this study was to investigate whether brain capillary endothelial cells (BCEC) respond to NGF and whether pro-inflammatory substances induce the secretion of NGF in these cells. Cells were incubated with
Karma V, Moser +3 more
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Nerve growth factor (NGF) is an important factor regulating survival in development and during regenerative or neuroinflammatory processes. The aim of this study was to investigate whether brain capillary endothelial cells (BCEC) respond to NGF and whether pro-inflammatory substances induce the secretion of NGF in these cells. Cells were incubated with
Karma V, Moser +3 more
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Molecular Brain Research, 2004
Mice lacking a functional NGF gene (ngf-/- mice) have less than one third of the normal complement of sensory neurons, few sympathetic postganglionic neurons and die shortly after birth. We report here that transgenic expression of NGF under control of the K14 keratin promoter can rescue some elements of the peripheral nervous system and restore normal
Susan M W, Harrison +5 more
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Mice lacking a functional NGF gene (ngf-/- mice) have less than one third of the normal complement of sensory neurons, few sympathetic postganglionic neurons and die shortly after birth. We report here that transgenic expression of NGF under control of the K14 keratin promoter can rescue some elements of the peripheral nervous system and restore normal
Susan M W, Harrison +5 more
openaire +2 more sources
2021
During the development of the nervous system, neurons respond to diffusible cues secreted by target cells. Because such target-derived factors regulate development, maturation, and maintenance of axons as well as somatodendritic compartments, signals initiated at distal axons must be retrogradely transmitted toward cell bodies. Neurotrophins, including
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During the development of the nervous system, neurons respond to diffusible cues secreted by target cells. Because such target-derived factors regulate development, maturation, and maintenance of axons as well as somatodendritic compartments, signals initiated at distal axons must be retrogradely transmitted toward cell bodies. Neurotrophins, including
openaire +2 more sources
Archives italiennes de biologie, 2011
Romantic love is the catalyst behind the spread of the human life. The neurobiology of love embraces the hypothesis that what we call "romantic attachment" or "romantic love" may be at least in part the expression of biological factors. A corollary of this hypothesis states that it is possible to learn much about the nature of human love by studying ...
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Romantic love is the catalyst behind the spread of the human life. The neurobiology of love embraces the hypothesis that what we call "romantic attachment" or "romantic love" may be at least in part the expression of biological factors. A corollary of this hypothesis states that it is possible to learn much about the nature of human love by studying ...
openaire +2 more sources