Biomedicines, 2021 A six-month double-blind, placebo-controlled randomized study was conducted to ascertain whether low-dose daily niacin supplementation would improve motor symptoms in Parkinson’s disease (PD) patients.
Chandramohan Wakade +5 more
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Niacin inhibits vascular calcification via modulating of SIRT1/SIRT6 signaling pathway [PDF]
Cell Death DiscoveryVascular calcification (VC) is a common pathological state that often accompanies calcium-phosphorus metabolism disorder and chronic kidney diseases (CKDs).
Chao-hua Kong +11 more
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Niacin Attenuates Pulmonary Hypertension Through H-PGDS in Macrophages
Circulation Research, 2020 Supplemental Digital Content is available in the text. Rationale: Pulmonary arterial hypertension (PAH) is characterized by progressive pulmonary vascular remodeling, accompanied by varying degrees of perivascular inflammation.
Peiyuan Bai, Jiao Liu, Jing Wang
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Association of dietary niacin intake with all-cause and cardiovascular mortality: National Health and Nutrition Examination Survey (NHANES) 2003–2018 [PDF]
Scientific ReportsThe long-term health impacts of niacin are still debated, and the association between dietary niacin and mortality risk in populations hasn’t been extensively explored.
Ling Lin +8 more
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Association between dietary niacin intake and suicidal ideation: mediating role of C-reactive protein [PDF]
BMC PsychiatryBackground While dietary niacin intake is acknowledged for its beneficial impact on mental health, the precise relationship between dietary niacin intake and suicidal ideation (SI) remains unclear.
Hao Lin +5 more
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Niacin enhances hematoma clearance and neurological recovery via the HCAR2/SIRT1/Nrf2 pathway after germinal matrix hemorrhage [PDF]
Redox BiologyGerminal matrix hemorrhage (GMH) is a common form of neonatal stroke in preterm infants and often results in severe and lasting neurological deficits. Persistent hematoma is a key contributor to secondary brain injury.
Xiong Liu +10 more
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Effect of niacin monotherapy on high density lipoprotein composition and function
Lipids in Health and Disease, 2020 Background Niacin has modest but overall favorable effects on plasma lipids by increasing high density lipoprotein cholesterol (HDL-C) and lowering triglycerides.
Scott M. Gordon +8 more
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Research, 2019 Niacin metal-organic frameworks (MOFs) encapsulated microcapsules with alginate shells and copper-/zinc-niacin framework cores were in situ synthesized by using a microfluidic electrospray approach for wound healing.
Guopu Chen +8 more
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Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy [PDF]
Cell Metabolism, 2020 Eija Pirinen +17 more
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