Results 61 to 70 of about 48,088 (233)

The effect of dietary niacin deficiency on reproduction of European brown hares: An experimental study

Frontiers in Ecology and Evolution, 2023
Large plots of maize in agricultural landscapes are associated with reduced reproductive output of females and impaired population development of free-living populations of European brown hares (Lepus europaeus, Pallas 1778).
Aldin Selimovic, Mathilde L. Tissier, Gabrielle Stalder, Johanna Painer-Gigler, Anna Haw, Hanna Rauch, Walter Arnold   +6 more
doaj   +1 more source

Predicting OCT2/MATEs‐Mediated Drug Interactions in Healthy Volunteers and Patients with Chronic Kidney Disease: Insights from Extended Clearance Concept, Endogenous Biomarkers, and In Vitro Inhibition Studies (Perspectives from the International Transporter Consortium)

Clinical Pharmacology &Therapeutics, EarlyView.
Organic cation transporter (OCT) 2 and multidrug and toxin extrusion (MATE) transporters play significant roles in the renal secretion of organic cations and drug–drug interactions (DDIs). Recent in vitro studies indicate that the Ki values for OCT2 exhibit substrate dependency and increase in potency with pre‐incubation.
Satoshi Asano, Aleksandra Galetin, Yoshiko Tomita, Kathleen M. Giacomini, Xiaoyan Chu, Xinning Yang, Toshimichi Nakamura, Hiroyuki Kusuhara, Yuichi Sugiyama   +8 more
wiley   +1 more source

Niacin and Butyrate: Nutraceuticals Targeting Dysbiosis and Intestinal Permeability in Parkinson’s Disease

Nutrients, 2020
Dysbiosis is implicated by many studies in the pathogenesis of Parkinson’s disease (PD). Advances in sequencing technology and computing have resulted in confounding data regarding pathogenic bacterial profiles in conditions such as PD.
T. Karunaratne, Chijioke Okereke, M. Seamon, S. Purohit, C. Wakade, Amol Sharma   +5 more
semanticscholar   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Insects as Food and Feed Source: A Comprehensive Review on Nutritional Value, Food Safety Concern, Environmental Benefits, Economic Potential, Technological Innovations, Challenges, and Future Prospects

Food Frontiers, EarlyView.
Edible insects offer a sustainable protein source, requiring fewer resources than traditional livestock. Despite challenges, they have the potential to enhance food security and sustainability for a growing global population. ABSTRACT As the world faces an escalating protein crisis amid climate change, population growth, and resource scarcity, edible ...
Anil Gautam, Ishwari Gyawali, Sushma Poudel, Sachin Devkota, Rabin Acharya, Milan Kandel, Deepak Subedi   +6 more
wiley   +1 more source

Effect of Different Levels of Niacin on Serum Biochemical Parameters, Antioxidant Status, Cytokine Levels, Inflammatory Gene Expression and Colonic Microbial Composition in Weaned Piglets [PDF]

, 2022
Zhaobin Wang, Zhenfeng Yi, Qiye Wang, Lanmei Yin, Jun Li, Junyan Xie, Huansheng Yang, Yulong Yin   +7 more
openalex   +1 more source

Niacin increases adiponectin and decreases adipose tissue inflammation in high fat diet-fed mice.

PLoS ONE, 2013
AimsTo determine the effects of niacin on adiponectin and markers of adipose tissue inflammation in a mouse model of obesity.Materials and methodsMale C57BL/6 mice were placed on a control or high-fat diet (HFD) and were maintained on such diets for the ...
Desiree Wanders, Emily C Graff, B Douglas White, Robert L Judd   +3 more
doaj   +1 more source

Niacin as a drug repositioning candidate for hyperphosphatemia management in dialysis patients

Therapeutics and Clinical Risk Management, 2014
Sooyoung Shin, Sukhyang LeeAjou University College of Pharmacy, Yeongtong-gu, Suwon-si, Gyeonggi-do, Korea Abstract: Nearly all patients with end-stage renal disease develop hyperphosphatemia.
Shin S, Lee S
doaj  

Effects of dietary niacin on liver health in genetically improved farmed tilapia (Oreochromis niloticus)

Aquaculture Reports, 2020
Pharmacological doses of niacin can improve lipid metabolism in humans and some homothermal model organisms, but flushing and hepatotoxicity are the main side-effects.
Wei Liu, Xing Lu, Ming Jiang, Fan Wu, Juan Tian, Lijuan Yu, Hua Wen   +6 more
doaj   +1 more source

FIGO good practice recommendations on anemia in pregnancy, to reduce the incidence and impact of postpartum hemorrhage (PPH)

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Anemia affects 32 million pregnant women globally, contributing annually to more than 115 000 maternal deaths and 591 000 perinatal deaths worldwide. Low‐ and middle‐income countries (LMICs) bear the highest burden of anemia in pregnancy, with nearly 50% of affected pregnant women. It is now 2025, which is WHO's target year for a 50% reduction
Akaninyene E. Ubom, Ferdousi Begum, Diana Ramasauskaite, Albaro J. Nieto‐Calvache, Monica Oguttu, Inês Nunes, Zechariah J. Malel, Jolly Beyeza‐Kashesya, Alison Wright, on behalf of the FIGO Committee on Childbirth and Postpartum Hemorrhage   +9 more
wiley   +1 more source