Results 11 to 20 of about 226,714 (349)

The use of Nicotinamide in Parkinson’s disease; A Possible path to the future. Review Article [PDF]

open access: yesArchives of Pharmaceutical Sciences Ain Shams University, 2023
Increasing the prevalence of Parkinson’s disease is an alarming sign that needs attention, so focusing on new medications and regimens which play an important role in prevention and treatment becomes a point of concern.
Sarah F Fahmy   +8 more
doaj   +1 more source

Fate of Nicotinamide Differs Due to an Intake of Nicotinamide [PDF]

open access: yesBioscience, Biotechnology, and Biochemistry, 1996
We found that the catabolism of nicotinamide (Nam) differs due to an intake of Nam itself in rats. When rats were fed with a Nam-free, tryptophan-limiting diet, the major catabolite of niacin was N1-methyl-4-pyridone-3-carboxamide (4-Py). However, its percentage was changed with increasing the intake of Nam.
Hisako Shimada   +2 more
openaire   +3 more sources

Nicotinamide Ameliorates Amyloid Beta-Induced Oxidative Stress-Mediated Neuroinflammation and Neurodegeneration in Adult Mouse Brain

open access: yesBiomedicines, 2021
Alzheimer’s disease (AD) is the most predominant age-related neurodegenerative disease, pathologically characterized by the accumulation of aggregates of amyloid beta Aβ1–42 and tau hyperphosphorylation in the brain.
Inayat Ur Rehman   +8 more
doaj   +1 more source

Nicotinamide, a Poly [ADP-Ribose] Polymerase 1 (PARP-1) Inhibitor, as an Adjunctive Therapy for the Treatment of Alzheimer’s Disease

open access: yesFrontiers in Aging Neuroscience, 2020
Nicotinamide (vitamin B3) is a key component in the cellular production of Nicotinamide Adenine Dinucleotide (NAD) and has long been associated with neuronal development, survival and death.
Felipe Salech   +12 more
doaj   +1 more source

doi: http://dx.doi.org/10.15407/ubj86.04.138 [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2014
Connective tissue is highly susceptible to imbalances induced by diabetes. Diabetes-related osteopenia, decreased bone strength etc. may be associated with altered metabolism of various collagens. Although it is assumed that alterations in collagen amino
M. M. Guzyk   +4 more
doaj   +1 more source

Nicotinamide Improves Cognitive Function in Mice With Chronic Cerebral Hypoperfusion

open access: yesFrontiers in Neurology, 2021
Normal brain function requires steady blood supply to maintain stable energy state. When blood supply to the brain becomes suboptimal for a long period of time, chronic cerebral hypoperfusion (CCH) and a variety of brain changes may occur.
Bin Liu   +3 more
doaj   +1 more source

The Role of NAD+ in Metabolic Regulation of Adipose Tissue: Implications for Obesity-Induced Insulin Resistance

open access: yesBiomedicines, 2023
Obesity-induced insulin resistance is among the key factors in the development of type 2 diabetes, atherogenic dyslipidemia and cardiovascular disease. Adipose tissue plays a key role in the regulation of whole-body metabolism and insulin sensitivity. In
Tatjana Ruskovska, David A. Bernlohr
doaj   +1 more source

Nicotinamide Deteriorates Post-Stroke Immunodepression Following Cerebral Ischemia–Reperfusion Injury in Mice

open access: yesBiomedicines, 2023
(1) Background: Inducing experimental stroke leads to biphasic immune responses, where the early activation of immune functions is followed by severe immunosuppression accompanied by spleen and thymus atrophy.
Shih-Huang Tai   +6 more
doaj   +1 more source

Nicotinamide Content of Insects [PDF]

open access: yesAustralian Journal of Biological Sciences, 1965
Surprisingly little is known of the vitamin content of insects and consequently, as part of an investigation of the function and metabolism of insect tissues, we have determined the nicotinamide content of a wide range of adult insects collected locally in the Wellington district.
MH Briggs, GB Kitto
openaire   +3 more sources

Effect of a mixture of caffeine and nicotinamide on the solubility of vitamin (B2) in aqueous solution [PDF]

open access: yes, 2006
The effect of caffeine (CAF) and nicotinamide (NMD) on the solubility of a vitamin B2 derivative (FMN) has been evaluated for mixtures containing either a single hydrotrope (CAF or NMD) or the two hydrotropes simultaneously.
A.A. Hernandez Santiago   +22 more
core   +1 more source

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