Results 21 to 30 of about 256,874 (388)

The use of Nicotinamide in Parkinson’s disease; A Possible path to the future. Review Article [PDF]

Archives of Pharmaceutical Sciences Ain Shams University, 2023
Increasing the prevalence of Parkinson’s disease is an alarming sign that needs attention, so focusing on new medications and regimens which play an important role in prevention and treatment becomes a point of concern.
Sarah F Fahmy, Mona Alshahawy, Nourhan Mohamed, Nora Gamal, Samar Abdelazim, Nadia Abdelsalam, Hend Abdelrahim, Reem H Shehab , Lamia El Wakeel   +8 more
doaj   +1 more source

Nicotinamide Deteriorates Post-Stroke Immunodepression Following Cerebral Ischemia–Reperfusion Injury in Mice

Biomedicines, 2023
(1) Background: Inducing experimental stroke leads to biphasic immune responses, where the early activation of immune functions is followed by severe immunosuppression accompanied by spleen and thymus atrophy.
Shih-Huang Tai, Liang-Chun Chao, Sheng-Yang Huang, Hsiao-Wen Lin, Ai-Hua Lee, Yi-Yun Chen, E-Jian Lee   +6 more
doaj   +1 more source

Potent Inhibition of Nicotinamide N-Methyltransferase by Alkene-Linked Bisubstrate Mimics Bearing Electron Deficient Aromatics

Journal of Medicinal Chemistry, 2021
Nicotinamide N-methyltransferase (NNMT) methylates nicotinamide (vitamin B3) to generate 1-methylnicotinamide (MNA). NNMT overexpression has been linked to a variety of diseases, most prominently human cancers, indicating its potential as a therapeutic ...
Yongzhi Gao, M. V. van Haren, Ned P Buijs, P. Innocenti, Yurui Zhang, D. Sartini, R. Campagna, M. Emanuelli, R. Parsons, W. Jespers, H. Gutiérrez‐de‐Terán, G. V. van Westen, N. Martin   +12 more
semanticscholar   +1 more source

Standardization of type 1 and type 2 diabetic nephropathy models in rats: Assessment and characterization of metabolic features and renal injury

Journal of Pharmacy and Bioallied Sciences, 2020
Background: Diabetes mellitus and its complications, such as nephropathy, represent a global burden. Recent research focuses on developing drugs that specifically target the pathogenesis of diabetic nephropathy rather than merely treating hyperglycemia ...
Aakruti A Kaikini, Divya Dhodi, Suraj Muke, Vaibhavi Peshattiwar, Sneha Bagle, Aruna Korde, Jayula Sarnaik, Vijay Kadwad, Satbir Sachdev, Sadhana Sathaye   +9 more
doaj   +1 more source

The Anion Impact on Dimensionality of Cadmium(II) Complexes with Nicotinamide

Chemistry, 2023
Three novel cadmium(II) coordination compounds, the dimeric [Cd(CH3COO)2(nia)2]2 (1), the polymeric {[Cd(nia)4](ClO4)2}n (2), and the monomeric [Cd(H2O)3(nia)3](ClO4)2·nia (3), were prepared in the reactions of the nicotinamide (pyridine-3-carboxamide ...
Željka Soldin, Boris-Marko Kukovec, Milica Kovačić, Marijana Đaković, Zora Popović   +4 more
doaj   +1 more source

It takes two to tango: NAD+ and sirtuins in aging/longevity control [PDF]

, 2016
The coupling of nicotinamide adenine dinucleotide (NAD+) breakdown and protein deacylation is a unique feature of the family of proteins called ‘sirtuins.’ This intimate connection between NAD+ and sirtuins has an ancient origin and provides a ...
Guarente, Leonard, Imai, Shin-ichiro
core   +2 more sources

Nicotinamide Content of Insects [PDF]

Australian Journal of Biological Sciences, 1965
Surprisingly little is known of the vitamin content of insects and consequently, as part of an investigation of the function and metabolism of insect tissues, we have determined the nicotinamide content of a wide range of adult insects collected locally in the Wellington district.
MH Briggs, GB Kitto
openaire   +3 more sources

BST1 regulates nicotinamide riboside metabolism via its glycohydrolase and base-exchange activities

Nature Communications, 2021
Nicotinamide riboside (NR) is one of the orally bioavailable NAD+ precursors and has been demonstrated to exhibit beneficial effects against aging and aging-associated diseases.
Keisuke Yaku, Sailesh Palikhe, Hironori Izumi, Tomoyuki Yoshida, Keisuke Hikosaka, Faisal Hayat, M. Karim, Tooba Iqbal, Yasuhito Nitta, A. Sato, M. Migaud, K. Ishihara, Hisashi Mori, T. Nakagawa   +13 more
semanticscholar   +1 more source

Nicotinamide Ameliorates Amyloid Beta-Induced Oxidative Stress-Mediated Neuroinflammation and Neurodegeneration in Adult Mouse Brain

Biomedicines, 2021
Alzheimer’s disease (AD) is the most predominant age-related neurodegenerative disease, pathologically characterized by the accumulation of aggregates of amyloid beta Aβ1–42 and tau hyperphosphorylation in the brain.
Inayat Ur Rehman, Riaz Ahmad, Ibrahim Khan, Hyeon Jin Lee, Jungsung Park, Rahat Ullah, Myeong Jun Choi, Hee Young Kang, Myeong Ok Kim   +8 more
doaj   +1 more source

Effect of a mixture of caffeine and nicotinamide on the solubility of vitamin (B2) in aqueous solution [PDF]

, 2006
The effect of caffeine (CAF) and nicotinamide (NMD) on the solubility of a vitamin B2 derivative (FMN) has been evaluated for mixtures containing either a single hydrotrope (CAF or NMD) or the two hydrotropes simultaneously.
A.A. Hernandez Santiago, Coffman, Coffman, D.B. Davies, Datta, Davies, Evstigneev, Evstigneev, Fawzi, Hussain, Jain, Khalil, Larsen, Lim, M.P. Evstigneev, Rasool, Redenti, Ribeiro, V.P. Evstigneev, Veselkov, Veselkov, Veselkov, Veselkov   +22 more
core   +1 more source