Results 31 to 40 of about 142,436 (357)
Neural Regeneration ResearchNeonatal hypoxic-ischemic brain injury is the main cause of hypoxic-ischemic encephalopathy and cerebral palsy. Currently, there are few effective clinical treatments for neonatal hypoxic-ischemic brain injury.
Xiaowen Xu +7 more
doaj +1 more source
Early Evolutionary Selection of NAD Biosynthesis Pathway in Bacteria
Metabolites, 2022 Bacteria use two alternative pathways to synthesize nicotinamide adenine dinucleotide (NAD) from nicotinamide (Nam). A short, two-step route proceeds through nicotinamide mononucleotide (NMN) formation, whereas the other pathway, a four-step route ...
Suraj Sharma +6 more
doaj +1 more source
Effects of NAD at purine receptors in isolated blood vessels [PDF]
, 2014 Nicotinamide adenine dinucleotide (NAD) belongs to the family of naturally occurring adenine dinucleotides, best known for their various intracellular roles.
Alefishat, Eman +2 more
core +2 more sources
Nicotinamide adenine dinucleotide is transported into mammalian mitochondria
eLife, 2018 Mitochondrial NAD levels influence fuel selection, circadian rhythms, and cell survival under stress. It has alternately been argued that NAD in mammalian mitochondria arises from import of cytosolic nicotinamide (NAM), nicotinamide mononucleotide (NMN),
Antonio Davila +9 more
doaj +1 more source
A Fluorescent Analog of Nicotinamide Adenine Dinucleotide [PDF]
Proceedings of the National Academy of Sciences, 1972 Nicotinamide 1, N 6 -ethenoadenine dinucleotide, a fluorescent analog of the coenzyme nicotinamide adenine dinucleotide, has been synthesized by the reaction of chloroacetaldehyde with the coenzyme. The technical fluorescence emission maximum of the analog is 410 nm, upon excitation at 300 nm.
J R, Barrio, J A, Secrist, N J, Leonard
openaire +2 more sources
Decreased myocardial injury and improved contractility after administration of a peptide derived against the alpha-interacting domain of the L-type calcium channel. [PDF]
, 2014 BackgroundMyocardial infarction remains the leading cause of morbidity and mortality associated with coronary artery disease. The L-type calcium channel (IC a-L) is critical to excitation and contraction.
Hool, Livia C +3 more
core +1 more source
Nicotinamide adenine dinucleotide biosynthesis promotes liver regeneration [PDF]
Hepatology, 2016 The regenerative capacity of the liver is essential for recovery from surgical resection or injuries induced by trauma or toxins. During liver regeneration, the concentration of nicotinamide adenine dinucleotide (NAD) falls, at least in part due to metabolic competition for precursors.
Sarmistha, Mukherjee +7 more
openaire +2 more sources
Dysregulation of NAD+ metabolism induces a Schwann cell dedifferentiation program [PDF]
, 2018 The Schwann cell (SC) is the major component of the peripheral nervous system (PNS) that provides metabolic and functional support for peripheral axons. The emerging roles of SC mitochondrial function for PNS development and axonal stability indicate the
Hackett, Amber R +4 more
core +1 more source
Performance Assessment of UVAPS: Influence of Fungal Spore Age and Air Exposure [PDF]
, 2007 This work focused on two main outcomes. The first was the assessment of the response of the Ultraviolet Aerodynamic Particle Sizer Spectrometer (UVAPS) for two different fungal spore species.
Agranovski +36 more
core +2 more sources
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source