Results 11 to 20 of about 3,705 (161)

A Mixture of Topical Forms of Polydeoxyribonucleotide, Vitamin C, and Niacinamide Attenuated Skin Pigmentation and Increased Skin Elasticity by Modulating Nuclear Factor Erythroid 2-like 2

open access: yesMolecules, 2022
It is well-known that increased oxidative stress caused by ultraviolet B (UV-B) radiation induces melanogenesis and activates metalloproteinases (MMPs), which degrade collagen and elastin fibers, leading to decreased skin elasticity.
Hyoung Moon Kim   +7 more
doaj   +3 more sources

Axillary Hyperpigmentation Treatment: A Systematic Review of the Literature. [PDF]

open access: yesJ Cosmet Dermatol
ABSTRACT Introduction Post‐inflammatory hyperpigmentation is a common dermatologic complaint that affects different parts of the body. Axillary hyperpigmentation (AH) is a common dermatologic complaint, with no standard treatment. We aim to address the efficacy and safety of the studied treatment modalities for AH.
Vahabi SM   +5 more
europepmc   +2 more sources

Mechanistic Insights into the Multiple Functions of Niacinamide: Therapeutic Implications and Cosmeceutical Applications in Functional Skincare Products

open access: yesAntioxidants
Niacinamide (or nicotinamide) is a small-molecule hydrosoluble vitamin with essential metabolic functions in mammalian cells. Niacinamide has become a key functional ingredient in diverse skincare products and cosmetics. This vitamin plays a pivotal role
Cíntia Marques   +8 more
doaj   +3 more sources

Niacinamide Antimicrobial Efficacy and Its Mode of Action via Microbial Cell Cycle Arrest

open access: yesMicroorganisms
Niacinamide is a versatile compound widely used in the personal care industry for its ample skin benefits. As a precursor to nicotinamide adenine dinucleotide (NAD+), essential for ATP production and a substrate for poly-ADP-ribose polymerase-1 (PARP-1),
Noa Ziklo   +3 more
doaj   +3 more sources

Use of Dermocosmetics in Acne Management: A Middle East-North Africa Consensus. [PDF]

open access: yesInt J Dermatol
ABSTRACT Background Acne in the Middle East and Northern Africa (MENA) is associated with high rates of post‐inflammatory hyperpigmentation and scarring, resulting from relatively high frequencies of darker or oily skin types, environmental factors, perceptions, and knowledge of acne and its treatment.
Zimmo S   +7 more
europepmc   +2 more sources

Niacin as a drug repositioning candidate for hyperphosphatemia management in dialysis patients [PDF]

open access: yesTherapeutics and Clinical Risk Management, 2014
Sooyoung Shin, Sukhyang LeeAjou University College of Pharmacy, Yeongtong-gu, Suwon-si, Gyeonggi-do, Korea Abstract: Nearly all patients with end-stage renal disease develop hyperphosphatemia.
Shin S, Lee S
doaj   +3 more sources

Integrative transcriptomics and metabolomics reveal neuroendocrine-lipid crosstalk and adenosine signaling in broiler under heat stress [PDF]

open access: yesBMC Genomics
Background Heat stress (HS) is a significant challenge in poultry, negatively impacting feed efficiency and survival. These adaptive responses could lead to disrupted lipid metabolism, impaired immunity, and neural damage.
Bingxing An   +6 more
doaj   +2 more sources

Niacin or niacinamide? Nicotinic acid or nicotinamide? What is the difference?

open access: bronzeJournal of the American Academy of Dermatology, 1986
Richard E. Ranchoff, Kenneth J. Tomecki
openalex   +3 more sources

Sirtuins as a potential molecular target of cosmetic ingredients [PDF]

open access: yesFarmacja Polska, 2022
Sirtuins are a group of enzymes belonging to histone deacetylases. However, they can also catalyze other deacylation reactions (including, for example, demallonylation, desuccinylation or deglutarylation), as well as ADP-ribosylation reactions.
Katarzyna Brezdeń   +2 more
doaj   +1 more source

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