Results 21 to 30 of about 2,780 (117)

Xeroderma pigmentosum: an updated review

Drugs in Context, 2022
Background: Early recognition of xeroderma pigmentosum is important to minimize the complications arising from the harmful effects of exposure to ultraviolet radiation.
Alexander KC Leung, Benjamin Barankin, Joseph M Lam, Kin Fon Leong, Kam Lun Hon   +4 more
doaj   +1 more source

Effect of Gamma Ray Irradiation Combined with VC and Niacinamide on Nitrite Degradation in Spiced Donkey Meat [PDF]

Shipin Kexue
Ion chromatography was used to investigate the effects of γ-ray irradiation dose, vitamin C (VC) content and niacinamide content on nitrite degradation in aqueous solution and spiced donkey meat, and the volatile components of irradiated spiced donkey ...
ZHAO Zhilei, LI Haoxuan, NIU Xiaoying, CHEN Meng, PANG Yanping,
doaj   +1 more source

Determination and uncertainty analysis of B vitamins in infant formula by HPLC-DAD/FLD [PDF]

Zhongguo niangzao
A method was developed for the simultaneous determination of vitamin B2 , niacin, nicotinamide, pyridoxine and pyridoxal in infant formula by HPLC. The sample was extracted by 0.1% phosphoric acid aqueous solution of 1% methanol and precipitated protein,
KANG Cuixin, ZHOU Yuan, MEI Rong, LIU Huibing, NIE Yi, MAO Yanni
doaj   +1 more source

Nicotinamide (aka Niacinamide) Mitigates SASP-Related Inflammation Induced by Environmental Stressors in Human Epidermal Keratinocytes

, 2020
Daily exposure of skin to environmental stressors leads to molecular and morphological changes ascribed as premature aging. These stressors include solar radiation, industrial pollution, fossil fuel and carbon emissions, which cause cellular damage that induces an inflammatory response in skin.
John C. Bierman, Timothy Laughlin, Makio Tamura, Ben C. Hulette, Catherine E. Mack, Christina Y. R. Tan, Malgorzata Morenc, Sophie Bellanger, John E. Oblong   +8 more
openaire   +2 more sources

Design and development of niacinamide lipid and polymeric nanoparticles and in vitro permeation studies using human epidermis [PDF]

RSC Pharmaceutics
Niacinamide (NIAC), also known as nicotinamide, is a Biopharmaceutics Classification System (BCS) Class I compound with versatile known dermatological benefits, including anti-inflammatory, antioxidant, brightening, and skin barrier-restoring effects ...
Dimitra Bompou, Emanuela Di Biase, Alexandra Sarika, Efstathia Triantafyllopoulou, Natassa Pippa, Dimitrios M. Rekkas, Paraskevas P. Dallas   +6 more
doaj   +1 more source

Examining the safety of nicotinamide for skin cancer prevention: Review of adverse events, metabolism, and toxic dosages

JAAD Reviews
Nicotinamide (niacinamide) supplementation for non-melanoma skin cancer prevention has sparked controversy over the past decade due to its inconsistent evidence of chemoprevention and its recently challenged safety profile.
Katie R. Xu, BA, Micah Belzberg, MD, Allison T. Vidimos, MD, RPh   +2 more
doaj   +1 more source

Vascularized Liver‐on‐a‐Microsphere Reveals Alanine‐Glucose Metabolism‐Driven Regulation of Liver Function and Injury

Advanced Science, EarlyView.
A vascularized liver‐on‐a‐microsphere system is developed to recreate lobule‐like cellular organization and endothelial barrier function within compartmentalized hydrogel particles. The platform enhances hepatic performance and reveals alanine‐glucose cycle activation linked to improved detoxification capacity, offering a high‐throughput microscale ...
Jingyang Li, Zengnan Wu, Yingrui Zhang, Shulang Chen, Yongning Lin, Shiyu Chen, Tong Xu, Xianli Meng, Yi Zhang, Jin‐Ming Lin   +9 more
wiley   +1 more source

Rotenone Induces Morphological Damage and Reduction in Catecholamine Levels in the Central Nervous System of the Ascidian Styela plicata

Environmental Toxicology, EarlyView.
ABSTRACT Ascidians are invertebrates that occupy a key phylogenetic position as a sister group of the vertebrates. The organization of their central nervous system (CNS), with cortex and medulla, indicates a plesiomorphic character of the gray and white matter of vertebrates, making this group of animals useful for studies of neurodegenerative events ...
Andressa de Abreu Mello, Carlos Augusto Borges de Andrade Gomes, Rafaela Rocha dos Santos, Cintia Monteiro de Barros, Silvana Allodi   +4 more
wiley   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source

Metabolomes of mitochondrial diseases and inclusion body myositis patients: treatment targets and biomarkers

EMBO Molecular Medicine, 2018
Mitochondrial disorders (MDs) are inherited multi‐organ diseases with variable phenotypes. Inclusion body myositis (IBM), a sporadic inflammatory muscle disease, also shows mitochondrial dysfunction.
Jana Buzkova, Joni Nikkanen, Sofia Ahola, Anna H Hakonen, Ksenia Sevastianova, Topi Hovinen, Hannele Yki‐Järvinen, Kirsi H Pietiläinen, Tuula Lönnqvist, Vidya Velagapudi, Christopher J Carroll, Anu Suomalainen   +11 more
doaj   +1 more source