Results 51 to 60 of about 458,722 (380)
Frontiers in Molecular Neuroscience, 2023 IntroductionNicotine dependence is one of the main causes of preventable diseases in the United States. Nicotine-seeking and avoidance behavioral assays in larval zebrafish could be used for identifying potential new pharmacotherapeutics in an early ...
Henning Schneider +6 more
doaj +1 more source
Nicotine and the nicotinic cholinergic system in COVID‐19 [PDF]
The FEBS Journal, 2020 There is an urgent need to address the devastating pandemic, COVID‐19, caused by SARS‐CoV‐2. The efforts to understand the details of this disease in hope of providing effective treatments are commendable. It is clear now that the virus can cause far more damage in patients with comorbid conditions—particularly in those with respiratory, cardiovascular,
Tizabi, Yousef +3 more
openaire +3 more sources
Inhibition of Autophagy Signaling via 3-methyladenine Rescued Nicotine-Mediated Cardiac Pathological Effects and Heart Dysfunctions. [PDF]
, 2020 Rationale: Cigarette smoking is a well-established risk factor for myocardial infarction and sudden cardiac death. The deleterious effects are mainly due to nicotine, but the mechanisms involved and theranostics remain unclear.
Fu, Yingjie +7 more
core
Endogenous cholinergic inputs and local circuit mechanisms govern the phasic mesolimbic dopamine response to nicotine [PDF]
, 2013 Nicotine exerts its reinforcing action by stimulating nicotinic acetylcholine receptors (nAChRs) and boosting dopamine (DA) output from the ventral tegmental area (VTA).
A Taly +78 more
core +5 more sources
Indian Journal of Psychiatry, 2023 Background: Nicotine replacement therapy (NRT) and habit cessation counseling are considered the mainstay treatment for high nicotine dependence smokers. However, adherence to NRT is very poor.
T Sivasankari +6 more
doaj +1 more source
Nicotine and nicotinic receptors in the circadian system
Psychoneuroendocrinology, 1998 Considerable data support a role for cholinergic influences on the circadian system. The extent to which these influences are mediated by nicotinic acetylcholine receptors (nAChRs) has been controversial, as have the specific actions of nicotine and acetylcholine in the suprachiasmatic nucleus (SCN) of the hypothalamus.
Thomas S. Kilduff +6 more
openaire +3 more sources
Adolescent Vaping and Nicotine Use in 2017-2018 - U.S. National Estimates.
New England Journal of Medicine, 2019 Adolescent Vaping and Nicotine Use in 2017–2018 A national survey revealed a large increase in nicotine vaping among high school students; more than 20% of 12th-graders reported that they vaped nic...
R. Miech +4 more
semanticscholar +1 more source
, 2002 It has been reported previously that leptin may be involved in nicotine\u27s ability to reduce body weight. Our aim was to investigate whether the anorexic action of nicotine is related to the actions of leptin by utilizing lean leptin-sensitive and ...
Cameron-Smith, David +3 more
core +1 more source
Substance use disorders in adolescents with attention deficit hyperactivity disorder: a 4-year follow-up study [PDF]
, 2013 Aim To examine the relationship between a childhood diagnosis of attention deficit hyperactivity disorder (ADHD) with or without oppositional defiant disorder (ODD)/conduct disorder (CD) and the development of later alcohol/drug use disorder ...
Buitelaar, JK +8 more
core +3 more sources
Current advances in research in treatment and recovery: Nicotine addiction
Science Advances, 2019 This review covers the changing tobacco product marketplace and evidence-based approaches to prevent and treat nicotine addiction. The health harms of combusted tobacco use are undeniable.
J. Prochaska, N. Benowitz
semanticscholar +1 more source