Results 81 to 90 of about 297,452 (281)

Unexpected loss of sensitivity to the nicotinic acetylcholine receptor antagonist activity of mecamylamine and dihydro‐β‐erythroidine in nicotine‐tolerant mice

Brain and Behavior, 2020
Objectives There is a long‐standing interest in developing nicotinic acetylcholine receptor (nAChR) antagonists for concomitant use with nAChR agonists (e.g., nicotine replacement) as complementary smoking cessation aids.
Fernando B. deMoura, Jenny L. Wilkerson, Lance R. McMahon   +2 more
doaj   +1 more source

Biochemical and genetic biomarkers associated with nicotine dependence in Mexican smokers

Pharmacology Research & Perspectives, 2023
Cigarette smoking remains an important health concern and is still a leading cause of preventable mortality. Nicotine is the substance responsible for sustained tobacco use and dependence.
Gissela Borrego‐Soto, Yadira Xitlalli Perez‐Paramo, Francisco Hernández‐Cabrera, Fatima Miroslaba Alvarado‐Monroy, Gilberto Borrego, Alejandro Robles‐Zamora, Philip Lazarus, Augusto Rojas‐Martinez   +7 more
doaj   +1 more source

Impact of a smoking ban in hospitality venues on second hand smoke exposure : a comparison of exposure assessment methods [PDF]

, 2013
In May 2010, Switzerland introduced a heterogeneous smoking ban in the hospitality sector. While the law leaves room for exceptions in some cantons, it is comprehensive in others.
Bauer, Georg F., Hoffmann, Susanne, Huynh, Cong Khanh, Rajkumar, Sarah, Röösli, Martin   +4 more
core   +4 more sources

Dual Functions of Dietary Rubber Seed Oil Supplementation: Enriching N‐3 Polyunsaturated Fatty Acids and Enhancing Antioxidant Capacity in Pekin Ducks

Animal Research and One Health, EarlyView.
Dietary RSO supplementation improved growth performance, simultaneously enriched n‐3 polyunsaturated fatty acids (n‐3 PUFA), and enhanced antioxidant capacity in Pekin ducks, which suggested that RSO has the potential to be a novel n‐3 PUFA source and an antioxidant for Pekin ducks to generate animal functional foods.
Lei Zhuang, Yongbao Wu, Zitao Zhao, Junting Cao, Yanhong Guo, Zhanyue Wu, Qimeng Wang, Peilong Yang, Sen Wu, Zhiguo Wen, Shuisheng Hou   +10 more
wiley   +1 more source

Overview of Encapsulated Lysine and Methionine and Their Impacts on Transition Cow Performance and Health

Animal Research and One Health, EarlyView.
The transition period in dairy cows, spanning 3 weeks before and after calving, is a critical phase characterized by increased nutrient demands, reduced dry matter intake (DMI), and elevated risk of metabolic disorders such as negative nutrient balance (NNB), lipolysis, proteolysis, and oxidative stress.
Mohammed S. Seleem, Samy A. Elsaadawy, Zhaohai Wu, Lu Ma, Todd R. Callaway, Dengpan Bu   +5 more
wiley   +1 more source

Interaction of the phencyclidine model of schizophrenia and nicotine on total and categorized ultrasonic vocalizations in rats [PDF]

, 2017
Patients with schizophrenia smoke cigarettes at a higher rate than the general population. We hypothesized that a factor in this comorbidity is sensitivity to the reinforcing and reinforcement- enhancement effects of nicotine.
Li, Ming, Mulholland, Michele M, Schulz, Tiffany D., Swalve, Natashia   +3 more
core   +1 more source

Targeted sequencing identifies genetic polymorphisms of flavin-containing monooxygenase genes contributing to susceptibility of nicotine dependence in European American and African American [PDF]

, 2017
BACKGROUND: Smoking is a leading cause of preventable death. Early studies based on samples of twins have linked the lifetime smoking practices to genetic predisposition.
Beuten, Bierut, Biesalski, Bloom, Boyle, Carmelli, Dickson, Doll, Doll, Feng, Gabriel, Gerra, Hall, Heatherton, Hecht, Hines, Hinrichs, Hong, Huang, Israni, Kennedy, Kremer, Krueger, Laniado-Laborín, Lee, Lerman, Liu, Mackillop, Mangold, Olfson, Park, Price, Pritchard, Pruim, Purcell, Quail, Ripley, Sabol, Saccone, Shafey, Szklarczyk, Thorgeirsson, Thorgeirsson, Tucker, Tønnesen, Uhl, Vink, Wang, World Health Organization, Xie   +49 more
core   +2 more sources

Drug‐Induced Raynaud's Phenomenon and Underlying Mechanism: A Disproportionality Analysis From the World Health Organization Pharmacovigilance Database

Arthritis &Rheumatology, EarlyView.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's phenomenon (RP) and to explore their potential pathophysiologic mechanisms through a mixed disproportionality/clustering analysis from the World Health Organization (WHO) pharmacovigilance database.
Alex Hlavaty, Loubna Dari, Jean‐Luc Cracowski, Matthieu Roustit, Charles Khouri   +4 more
wiley   +1 more source

CYP2A6 Polymorphisms May Strengthen Individualized Treatment for Nicotine Dependence

Scientifica, 2015
Each CYP2A6 gene variant metabolizes nicotine differently depending on its enzymatic activities. The normal nicotine metabolizer CYP2A6*1A is associated with high scores of nicotine dependence (5–10) on the Fagerström Test for Nicotine Dependence (FTND ...
Yawo Mawuli Akrodou
doaj   +1 more source

Prenatal Nicotine Exposure as a Teratogen in Neurological Pathways [PDF]

, 2016
Attention-deficit/hyperactivity disorder (ADHD) is the most heritable and commonly diagnosed childhood psychiatric disorder with 4% of all children being diagnosed with this disorder.
Grover, Monica
core   +1 more source