Results 41 to 50 of about 140,109 (356)

Commentary: Nicotinic acetylcholine receptor α9 and α10 subunits are expressed in the brain of mice [PDF]

open access: yes, 2018
Fil: Morley, Barbara J.. Boys Town National Research Hospita; Estados UnidosFil: Whiteaker, Paul. Barrow Neurological Institute; Estados UnidosFil: Elgoyhen, Ana Belen. Consejo Nacional de Investigaciones Científicas y Técnicas.
Elgoyhen, Ana Belen   +2 more
core   +1 more source

Discoveries and future significance of research into amyloid-beta/α7-containing nicotinic acetylcholine receptor (nAChR) interactions

open access: yesPharmacological Research, 2023
Initiated by findings that Alzheimer’s disease is associated with a profound loss of cholinergic markers in human brain, decades of studies have examined the interactions between specific subtypes of nicotinic acetylcholine receptors and amyloid-β ...
Paul Whiteaker, Andrew A. George
doaj  

Functional characterisation of a nicotinic acetylcholine receptor alpha subunit from the brown dog tick, Rhipicephalus sanguineus [PDF]

open access: yes, 2014
Open Access funded by Biotechnology and Biological Sciences Research Council Under a Creative Commons license This work was supported by a Biotechnology and Biological Sciences Research Council (UK) Industrial CASE studentship award (BBSSM200411428) to K.
Alan S. Bowman   +72 more
core   +3 more sources

Diversity of vertebrate nicotinic acetylcholine receptors [PDF]

open access: yesNeuropharmacology, 2009
Nicotinic acetylcholine receptors (nAChRs) are pentameric neurotransmitter receptors. They are members of the Cys-loop family of ligand-gated ion channels which also include ionotropic receptors for 5-hydroxytryptamine (5-HT), gamma-aminobutyric acid (GABA) and glycine.
Millar NS, Gotti C
openaire   +4 more sources

Signaling of nicotinic acetylcholine receptors in mononuclear phagocytes

open access: yesPharmacological Research, 2023
Nicotinic acetylcholine receptors are not only expressed by the nervous system and at the neuro-muscular junction but also by mononuclear phagocytes, which belong to the innate immune system.
Katrin Richter, Veronika Grau
doaj  

Identification and Characterization of a G Protein-binding Cluster in α7 Nicotinic Acetylcholine Receptors*

open access: yesJournal of Biological Chemistry, 2015
Background: α7 nicotinic acetylcholine receptors are ligand-gated ion channels that bind intracellular signaling proteins. Results: A mutation in the M3-M4 loop of the α7 nicotinic acetylcholine receptor abolishes Gαq activation of intracellular calcium ...
J. R. King   +4 more
semanticscholar   +1 more source

Nicotinic acetylcholine receptors in the synganglion of the tick Ixodes ricinus: Functional characterization using membrane microtransplantation

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2020
Nicotinic acetylcholine receptors are an important class of excitatory receptors in the central nervous system of arthropods. In the ticks Ixodes ricinus, the functional and pharmacological properties of nicotinic receptors located in their neurons are ...
Anaïs Le Mauff   +8 more
doaj  

Interactions between the rabies virus and nicotinic acetylcholine receptors: A potential role in rabies virus induced behavior modifications

open access: yesHeliyon, 2022
Rabies causes approximately 60,000 casualties annually and has a case fatality rate approaching 100% once clinical signs occur. The glycoprotein on the surface of the virion is important for the host immune response and facilitates interaction of the ...
Marianne Lian   +2 more
doaj  

Bispyridinium Compounds Inhibit Both Muscle and Neuronal Nicotinic Acetylcholine Receptors in Human Cell Lines. [PDF]

open access: yesPLoS ONE, 2015
Standard treatment of poisoning by organophosphorus anticholinesterases uses atropine to reduce the muscarinic effects of acetylcholine accumulation and oximes to reactivate acetylcholinesterase (the effectiveness of which depends on the specific ...
Avi Ring   +8 more
doaj   +1 more source

Coordination of opposing sex-specific and core muscle groups regulates male tail posture during Caenorhabditis elegans male mating behavior [PDF]

open access: yes, 2009
Background To survive and reproduce, animals must be able to modify their motor behavior in response to changes in the environment. We studied a complex behavior of Caenorhabditis elegans, male mating behavior, which provided a model for understanding ...
A Barrios   +45 more
core   +4 more sources

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