Enzymatic approaches to nicotinic acid synthesis: recent advances and future prospects [PDF]
Frontiers in Bioengineering and BiotechnologyBiocatalyst-mediated reactions have led to revolutionary transformations in the organic synthesis of pharmaceuticals, drugs, and other chemicals.
Rahul Vikram Singh +5 more
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THE BACTERIAL OXIDATION OF NICOTINIC ACID [PDF]
Journal of Biological Chemistry, 1957 N-Formylmaleamic acid, a probable intermediate in the bacterial metabolism of nicotinic acid, has been synthesized by photoisomerization of its transisomer, N-formylfumaramic acid. The compound previously reported to be N-formylmaleamic acid has been shown to be N-formylfumaramic acid.
Edward J. Behrman, R.Y. Stanier
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A New Method for the Determination of Nucleic Acid Using an Eu3+– nicotinic Acid Complex as a Resonance Light Scattering Probe [PDF]
Molecules, 2008 This study found that in Tris-HCl buffer, the resonance light scattering (RLS) intensity of the Eu3+-nicotinic acid system can be greatly enhanced by nucleic acids and the enhanced intensity is proportional to the concentration of nucleic acid in the ...
Jing-He Yang +4 more
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In silico prediction of some pharmacokinetic, safety, biological activity and molecular docking studies of 1-piperazine indole hybrid with nicotinic amide and nicotinic acid and their analogues [PDF]
SAGE Open MedicineBackground: In silico predictions are now being utilized in drug discovery and design to assess the physicochemical, pharmacokinetics, and safety properties of compounds at the beginning of the drug discovery process.
Melese Legesse Mitku +7 more
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Journal of Biological Chemistry, 1969 Abstract An enzyme that catalyzes the reversible hydroxylation of nicotinic acid to 6-hydroxynicotinic acid has been purified from extracts of a nicotinic acid-fermenting clostridium. The enzyme appears to be a flavin adenine dinucleotide-containing non-heme iron protein and utilizes triphosphopyridine nucleotide as the ultimate electron acceptor.
Earl R. Stadtman, John S. Holcenberg
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مجله دانشکده پزشکی اصفهان, 2021 Background: Reactive oxygen species (ROS) are of the most important detrimental factors on sperm quality during freezing process, which increases the lipid peroxidation (LPO) of cell membranes.
Zahra Sadeghi +2 more
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Solution thermodynamics of aqueous nicotinic acid solutions in presence of tetrabutylammonium hydrogen sulphate [PDF]
Journal of the Serbian Chemical Society, 2013 In this study we investigated the effects of tetrabutylammonium hydrogen sulphate (Bu4NHSO4) on the solute-solute and solute-solvent interactions in the aqueous solutions of nicotinic acid in terms of apparent molar volumes (φV), standard partial ...
Sarkar Abhijit, Sinha Biswajit
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Nicotinic acid: a lipid-lowering agent with unrealized potential
The Egyptian Journal of Internal Medicine, 2014 Nicotinic acid is a well-known treatment for dyslipidemia in adults. This review article explored not only the role of nicotinic acid in dyslipidemia but also its role in hypertension and as a cardioprotective agent.
Samar H. Aboulsoud
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Arachidonic Acid as a Possible Negative Feedback Inhibitor of Nicotinic Acetylcholine Receptors on Neurons [PDF]
, 1995 Neuronal acetylcholine receptors, being highly permeable to calcium, are likely to regulate calcium-dependent events in neurons. Arachidonic acid is a membrane-permeant second messenger that can be released from membrane phospholipids by phospholipases ...
Berg, Darwin K. +3 more
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