Results 101 to 110 of about 5,257,547 (397)
British Journal of Clinical Pharmacology, EarlyView.Aims Insomnia is a common sleep disorder, affecting up to 20% of the world population and adversely impacting productivity, health, and overall well‐being. Although pharmacologic options exist to treat insomnia, the health‐related quality of life for patients who are prescribed hypnotics is no higher than for those who are not, revealing a significant ...
Garth T. Whiteside +5 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.Succinic acid is produced by the fermentation of metabolically engineered Mannheimia succiniciproducens, purified, and used to synthesize poly(butylene succinate) using a two‐step process that involves the esterification of succinic acid and ethanol, followed by enzymatic transesterification of diethyl succinate and 1,4‐butanediol.
Ji Yeon Kim +4 more
wiley +1 more source
PLoS ONE, 2019 Bordetella bacteria are respiratory pathogens of humans, birds, and livestock. Bordetella pertussis the causative agent of whopping cough remains a significant health issue.
William T Booth +3 more
doaj +1 more source
Nicotinic acid and DP1 blockade: studies in mouse models of atherosclerosis[S]
Journal of Lipid Research, 2013 The use of nicotinic acid to treat dyslipidemia is limited by induction of a “flushing” response, mediated in part by the interaction of prostaglandin D2 (PGD2) with its G-protein coupled receptor, DP1 (Ptgdr).
Alison M. Strack +25 more
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Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application
BMEMat, EarlyView.The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah +9 more
wiley +1 more source
EFFECT OF NICOTINIC ACID ON PLASMA AND BODY PROTEINS AND LIPIDS IN BROILERS [PDF]
Journal of Veterinary and Animal Sciences, 2002 Numerous attempts were made to reduce carcass fat in broilers by genetic, nutritional and pharmacological manipulation in the past years, so as to reduce the incidence of coronary heart disease in consumers of broiler meat. In this study an attempt was
P. Hariharanl, B. Gowrishanker
doaj
Czech Journal of Food Sciences, 2009 Besides caffeine, the betaine N-methyl nicotinic acid, also known as trigonelline, is commonly reported as the second most abundant alkaloid in raw coffee beans.
R. Lang, T. Hofmann
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Experimental Biology and Medicine, 1938 SummaryNicotinic acid is at least several hundred times less toxic in mice, rats, and guinea pigs than nicotine. Nicotinic acid is devoid of action upon the autonomic ganglia. Nevertheless, repeated administration of large doses, 2 gm. daily, in dogs has resulted in poisoning and deaths.
Charles L. Rose +2 more
openaire +2 more sources
Deuteration of Six‐Membered N‐Heteroarenes: Chemistry and Applications
Chemistry – A European Journal, EarlyView.Deuterated six‐membered N‐Heteroarenes (6NHetAr) are finding utility in an increasing repertoire of applications. Our paper comprehensively reviews synthetic approaches that have been reported for the deuteration of 6NHetAr and their fused counterparts while providing an overview of established and emerging applications for these materials.
Liju Raju +4 more
wiley +1 more source
Pyridine nucleotide synthesis by rat adipose tissue in vitro
Journal of Lipid Research, 1967 The synthesis of NAD and NADP by rat adipose tissue was measured in vitro. Nicotinamide-7-14C and NaH232PO4 were incorporated together into NAD with a 32P/14C ratio of 1.82 and nicotinic-7-14C acid and NaH232PO4 with a ratio of 1.94.
Richard W. Hanson, Zigmund Z. Ziporin
doaj +1 more source