Results 121 to 130 of about 60,608 (292)

Nicotinic Acid Catabolism Modulates Bacterial Mycophagy in Burkholderia gladioli Strain NGJ1. [PDF]

Microbiol Spectr, 2023
Das J, Kumar R, Yadav SK, Jha G.
europepmc   +1 more source

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

Allergy, EarlyView.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng, Tao Lu, Ji Wang, Yalan Zhang, Panhui Xiong, Jieyu Zeng, Shuman Li, Yu Jiang, Yijun Liu, Longlan Shu, Yuan Chen, Yin Zhou, Yue Gu, Dayu Guan, Chenxi Li, Lei Zhao, Shujin Wang, Jie Liu, Xia Ke, Yang Shen, Yucheng Yang   +20 more
wiley   +1 more source

Nicotinic acid supplementation contributes to the amelioration of Alzheimer's disease in mouse models. [PDF]

Ann Transl Med, 2022
Wang Z, Zou Z, Li Q.
europepmc   +1 more source

Spatial Control of Ca2+ Signaling by Nicotinic Acid Adenine Dinucleotide Phosphate Diffusion and Gradients [PDF]

, 2000
Grant C. Churchill, Lianne C. Davis
openalex   +1 more source

Heat‐Not‐Burn Tobacco Aerosols Induce Immune Dysregulation and Barrier Disruption Comparable to Conventional Cigarettes

Allergy, EarlyView.
Comparative analysis between cigarette smokers and HnB users revealed similar inflammatory lung function parameters and immunophenotypic patterns. Cigarette smoke and HnB aerosol had an impact on ECM through divergent downstream pathways. Exposed to Cigarette smoke and HnB aerosol caused comparative TJ weakening in the epithelial barrier.
Dilara Karaguzel, Alicja Walewska, Basak Ezgi Sarac, Marlena Tynecka, Kinga Bondarczuk, Agnieszka Tarasik, Dariusz Kisiel, Karolina Partyk, Damian Pogodziński, Bartosz Hanczaruk, Alicja Toczydlowska, Cagla Bicakci, Doga Oztabak, Magdalena Niemira, Adam Kretowski, Marlena Dubatowka, Natalia Ogrodnik, Malgorzata Chlabicz, Pawel Sowa, Karol Kaminski, Marcin Moniuszko, Andrzej Eljaszewicz, Cagatay Karaaslan   +22 more
wiley   +1 more source

Blood levels of nicotinic acid negatively correlate with hearing ability in healthy older men. [PDF]

BMC Geriatr, 2023
Nakagawa-Nagahama Y, Igarashi M, Miura M, Kashiwabara K, Yaku K, Fukamizu Y, Sato T, Sakurai T, Nakagawa T, Kadowaki T, Yamauchi T.   +10 more
europepmc   +1 more source

THE SYNTHESIS OF NICOTINIC ACID BY THE RAT

, 1941
William John Dann
openalex   +1 more source

The chemical conversion of nicotinic acid and nicotinamide to derivatives of N-methyl-2-pyridone by methylation and oxidation [PDF]

, 1948
W. I. M. Holman, C. J. Wesley Wiegand
openalex   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

Supplemental Nicotinic Acid Elevates NAD⁺ Precursors in the Follicular Fluid of Mares. [PDF]

Animals (Basel), 2022
Pollard CL, Gibb Z, Clulow J, Ruiz A, Sheridan A, Bahrami M, Swegen A, Grupen CG.   +7 more
europepmc   +1 more source