Results 121 to 130 of about 5,257,547 (397)

Maternal Isoflavone‐S Improve Offspring Intestinal Homeostasis Through Maternal Metabolome–Microbiome Intestine Interactions in a Pig Model

open access: yesFood Frontiers, EarlyView.
Our results indicate that maternal ISO‐S during late gestation and throughout lactation can improve offspring intestinal homeostasis, which may be related to antioxidant enzymes and immunoglobulins in sow colostrum through maternal metabolome–microbiome intestine interactions.
Changming Hong   +9 more
wiley   +1 more source

Nicotinic Acid-Mediated Activation of Both Membrane and Nuclear Receptors towards Therapeutic Glucocorticoid Mimetics for Treating Multiple Sclerosis

open access: yesPPAR Research, 2009
Acute attacks of multiple sclerosis (MS) are most commonly treated with glucocorticoids, which can provide life-saving albeit only temporary symptomatic relief.
W. Todd Penberthy
doaj   +1 more source

Schizophrenia is a TH2 dominant autoimmune disease possibly against acetylcholine receptors of CNS [PDF]

open access: yes, 2012
Schizophrenia is a very common psychiatric disorder. However, its etiology and pathogenesis is still unknown. Current theory saying that neurotransmitter imbalance such as serotonin or dopamine only provides limited effectiveness in schizophrenia ...
Wanchung(Wan-Jiung) Hu
core   +1 more source

Toward Less Energy‐Consuming Alcoholic Fermentations in Oenology: A Laboratory‐Scale Case Study

open access: yesFood Frontiers, EarlyView.
The graphical abstract outlines the experimental workflow, from fermenting nine commercial yeast strains under different sugar concentrations and temperature programs, to systematic sampling and analysis of metabolites, volatiles, and cell populations, generating the dataset used to assess the impact of temperature dynamics on fermentation.
Romain Minebois   +3 more
wiley   +1 more source

Synthesis and Anti-Inflammatory Activity of New Nicotinoyl Amides

open access: yesEurasian Chemico-Technological Journal
The article presents the results of a study of the amination reaction of nicotinic acid chlorohydride with amines morpholine, cytisine, and 1-aminoadamantane, which are often used in the search and creation of drugs for respiratory and circulatory ...
O.A. Nurkenov   +6 more
doaj   +1 more source

Lateral Habenula contribution in Nicotine addiction : focus on Dopamine, GABA and Serotonin Interactions [PDF]

open access: yes, 2011
Compelling evidence has shown a pivotal role of dopaminergic function in drug addiction. Recently, the Habenula (Hb) has attracted a great deal of attention as another target for nicotine in the brain because of its role in regulating dopamine (DA ...
Benigno, Arcangelo   +6 more
core   +1 more source

Modulating Neurotoxic Effects of Prenatal Chlorpyrifos Exposure Through Probiotic and Vitamin D Gestational Supplementation: Unexpected Effects on Neurodevelopment and Sociability

open access: yesFood Frontiers, EarlyView.
This study investigates whether gestational probiotic and vitamin D supplementation can mitigate CPF effects in Wistar rats. While supplementation did not reverse CPF‐induced deficits, it induced notable neurodevelopmental changes in control animals, underscoring the need for further research on prenatal supplementation safety.
Mario Coca   +8 more
wiley   +1 more source

Effect of nicotinic acid on the survival rate, and neurodegeneration of transgenic Drosophila melanogasterwith overexpression of human APP gene

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2013
Transgenic Drosophila melanogaster lines modeling the main neuromorphological markers of Alzheimer's disease were used to study the neuroprotective properties of nicotinic acid.
O. I. Bolshakova   +4 more
doaj  

Two Amino Acid Residues Contribute to a Cation-π Binding Interaction in the Binding Site of an Insect GABA Receptor [PDF]

open access: yes, 2011
Cys-loop receptor binding sites characteristically possess an "aromatic box," where several aromatic amino acid residues surround the bound ligand. A cation-π interaction between one of these residues and the natural agonist is common, although the ...
Ashby, Jamie A.   +3 more
core  

Assessment of the Effects of Cigarette Smoke on the Renal Morphology of WISTAR Rats

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Smoking is a major public health concern worldwide. The toxic components of cigarettes, such as nicotine, can cause abuse, dependence, and tissue damage. This study aimed to evaluate the effects of exposure to cigarette smoke on the renal morphology of Wistar rats.
Cristiane Gomes Fernandes Freire   +9 more
wiley   +1 more source

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