Results 161 to 170 of about 481,268 (346)
d‐amino acids: new functional insights
This review explores recent advances in understanding d‐amino acids (d‐AAs) and their pivotal roles across organisms, from plants to humans. d‐AAs have been implicated in key physiological processes, including cancer, inflammation, immune regulation, kidney disease, diabetes, and nervous system function.
Loredano Pollegioni+5 more
wiley +1 more source
Channel blocking properties of a series of nicotinic cholinergic agonists
Inhibition of the nicotinic acetylcholine receptor (nAChR) by channel blockade has been demonstrated with a variety of large organic cations, including several nicotinic agonists. We have studied the kinetics of channel blocking of a series of agonists which vary systematically in size and hydrophobicity due to a hydrocarbon chain from one to six ...
Robert E. Oswald, Alison A. Carter
openaire +3 more sources
Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer+4 more
wiley +1 more source
Nicotine exposure is a risk factor in several breathing disorders Nicotinic acetylcholine receptors (nAChRs) exist in the ventrolateral medulla, an important site for respiratory control.
EIKI HATORI+7 more
doaj
Agonist-Antagonist Pouch Motors: Bidirectional Soft Actuators Enhanced by Thermally Responsive Peltier Elements [PDF]
In this study, we introduce a novel Mylar-based pouch motor design that leverages the reversible actuation capabilities of Peltier junctions to enable agonist-antagonist muscle mimicry in soft robotics. Addressing the limitations of traditional silicone-based materials, such as leakage and phase-change fluid degradation, our pouch motors filled with ...
arxiv +1 more source
Role of nicotine receptor partial agonists in tobacco cessation
One in three adults in India uses tobacco, a highly addictive substance in one or other form. In addition to prevention of tobacco use, offering evidence-based cessation services to dependent tobacco users constitutes an important approach in addressing this serious public health problem.
Pratima Murthy+2 more
openaire +3 more sources
Enteric neuropathy and the vagus nerve: Therapeutic implications
Abstract Enteric neuropathies are characterized by abnormalities of gut innervation, which includes the enteric nervous system, inducing severe gut dysmotility among other dysfunctions. Most of the gastrointestinal tract is innervated by the vagus nerve, the efferent branches of which have close interconnections with the enteric nervous system and ...
Bruno Bonaz
wiley +1 more source
: Activation of nicotinic acetylcholine receptors (nAChRs) induces nocotinic long-term potentiation (LTPn) in vivo in the mouse dentate gyrus. We have found that α4β2 nAChRs activated by epibatidine induce LTPn, the full size of which requires the ...
Shogo Matsuyama, Akira Matsumoto
doaj
THE EFFECT OF TUBOCURARINE COMPETITION ON THE KINETICS OF AGONIST ACTION ON THE NICOTINIC RECEPTOR [PDF]
David Colquhoun, Robert E. Sheridan
openalex +1 more source