Results 161 to 170 of about 493,465 (339)

Back Cover: Insight into the Binding Mode of Agonists of the Nicotinic Acetylcholine Receptor from Calculated Electron Densities (ChemPhysChem 13/2015) [PDF]

, 2015
Michael E. Beck, Oliver Gutbrod, Svend Matthiesen   +2 more
openalex   +1 more source

Test–retest reliability of Doppler ultrasound‐based leg blood flow assessments during exercise in patients with chronic obstructive pulmonary disease

Experimental Physiology, EarlyView.
Abstract Doppler ultrasound may be used to assess leg blood flow (Q̇leg${{\dot{Q}}_{{\mathrm{leg}}}}$), but the reliability of this method remains unexplored in patients with chronic obstructive pulmonary disease (COPD), where between‐subject variability may be larger than healthy due to peripheral vascular changes.
Milan Mohammad, Jacob P. Hartmann, Amalie B. Andersen, Helene L. Hartmeyer, Ulrik W. Iepsen, Ronan M. G. Berg   +5 more
wiley   +1 more source

GABAB receptor‐mediated modulation of sensory neuron excitability: Roles of CaV2.2, G‐protein‐coupled inwardly rectifying potassium (GIRK) channels, and hyperpolarisation‐activated cyclic nucleotide‐gated (HCN) channels in human and mouse nociception

Experimental Physiology, EarlyView.
Abstract Chronic visceral pain is a key symptom of irritable bowel syndrome. Modulation of voltage‐gated calcium and potassium channels by G protein‐coupled receptors plays a key role in dampening nociceptive transmission. Both baclofen and the analgesic peptide α‐conotoxin Vc1.1 activate GABAB receptors (GABABR), resulting in inhibition of CaV2.2 and ...
Mariana Brizuela, Anuja R. Bony, Sonia Garcia‐Caraballo, David J. Adams, Stuart M. Brierley   +4 more
wiley   +1 more source

α4β2 nicotinic acetylcholine receptor partial agonists with low intrinsic efficacy have antidepressant-like properties

, 2011
Yann S. Mineur, Emily B. Einstein, Patricia A. Seymour, Jotham W. Coe, Brian T. O’Neill, Hans Rollema, Marina R. Picciotto   +6 more
openalex   +2 more sources

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Deletion of the TRPV1 channel attenuates afferent renal nerve responses to renal artery occlusion but not elevated renal pelvic pressure

The Journal of Physiology, EarlyView.
Abstract figure legend Using wild‐type and Trpv1−/− rats, we assessed the contribution of TRPV1 channels to the activation of afferent renal nerve activity (ARNA) during renal artery occlusion, graded reductions in renal blood flow and elevated renal pelvic pressure.
Jacob B. Sullivan, Leon J. DeLalio, Sean D. Stocker   +2 more
wiley   +1 more source

Alpha-7 nicotinic agonist improves cognition in schizophrenia. [PDF]

Evid Based Ment Health, 2016
Marder SR.
europepmc   +1 more source

Effects of a Selective Cannabinoid CB2 Agonist and Antagonist on Intravenous Nicotine Self Administration and Reinstatement of Nicotine Seeking

, 2012
Islam Gamaleddin, A. M. Zvonok, Alexandros Makriyannis, Steven R. Goldberg, Bernard Le Foll   +4 more
openalex   +2 more sources

Binding Interactions of NS6740, a Silent Agonist of the α7 Nicotinic Acetylcholine Receptor [PDF]

, 2019
Catriona Emily Wilson Blunt, Dennis A. Dougherty   +1 more
openalex   +1 more source

Transient Inactivation of the Neonatal Ventral Hippocampus Impairs Attentional Set-Shifting Behavior: Reversal with an α7 Nicotinic Agonist

Neuropsychopharmacology, 2012
Julie M. Brooks, M. Pershing, M. S. Thomsen, J. Mikkelsen, M. Sarter, J. Bruno   +5 more
semanticscholar   +1 more source