Results 171 to 180 of about 41,965 (298)
THE EFFECT OF TUBOCURARINE COMPETITION ON THE KINETICS OF AGONIST ACTION ON THE NICOTINIC RECEPTOR [PDF]
, 1982 David Colquhoun, Robert E. Sheridan
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Food Safety and Health, Volume 4, Issue 1, Page 220-232, January 2026.Vanillin showed moderate sedative and modulatory synergistic activities on diazepam in thiopental sodium‐induced sleeping mice. These effects are implicated with GABAergic intervention. ABSTRACT Insomnia is a common sleep disorder affecting approximately 10% of adults.
Salehin Sheikh +8 more
wiley +1 more source
Treating schizophrenia symptoms with an α7 nicotinic agonist, from mice to men
, 2007 Ann Olincy, Karen E. Stevens
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Simulations Suggest a Structural Basis for Nicotinic Receptor Activation by Agonists [PDF]
, 2018 Sushree Tripathy +2 more
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Spirocyclic Diamine Scaffolds for Medicinal Chemistry
Helvetica Chimica Acta, Volume 109, Issue 1, January 2026.Here we enumerated 391 spirocyclic diamine drug scaffolds with ring sizes four to eight and found that most of them are unknown. We prepared four novel such spirocycles and discovered a micromolar inhibitor of the M4 muscarinic receptor. ABSTRACT Medicinal chemistry requires the exploration of structurally diverse compound families to expand the ...
Aline Carrel +3 more
wiley +1 more source
Journal of Applied Toxicology, Volume 46, Issue 1, Page 179-197, January 2026.ABSTRACT Neonicotinoids are widely used insecticides in agriculture, aquaculture, pet care, and urban pest control. Initially developed to selectively target the insect cholinergic system, their extensive use has raised concerns about adverse effects on nontarget vertebrates.
Kirthana Kunikullaya U +6 more
wiley +1 more source
Agonist Selectivity and Ion Permeation in the α3β4 Ganglionic Nicotinic Receptor [PDF]
, 2020 Anant Gharpure +9 more
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OTO Open, Volume 10, Issue 1, January-March 2026.Abstract Objective Glucagon‐like peptide 1 receptor agonists (GLP‐1RA) have shown remarkable results in glycemic control for patients with type 2 diabetes (T2DM). While no association has been made, there is a concern for thyroid cancer (TC) from GLP‐1RA. We aimed to study the 5‐year risk of TC in T2DM patients taking GLP‐1RA.
Bao Y. Sciscent +5 more
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Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 1, January 2026.ABSTRACT Post‐resuscitation cardiac arrest care begins at the time of hospital admission and focuses on preventing the sequelae of ischemia–reperfusion injury, including secondary brain damage and post‐cardiac arrest syndrome. Clinical practice guidelines on post‐resuscitation cardiac arrest care from international medical organizations outline ...
Christy Cecil Forehand +17 more
wiley +1 more source
Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 1, January/March 2026.Abstract INTRODUCTION Repurposing Food and Drug Administration (FDA)‐approved drugs could accelerate treatment development for Alzheimer's disease (AD). METHODS Using the MarketScan claims database (2011 to 2020), we applied a trial emulation approach in two base cohorts: (1) individuals with mild cognitive impairment (MCI cohort) and (2) individuals ...
Reina Tonegawa‐Kuji +10 more
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