Results 171 to 180 of about 481,268 (346)

Spontaneous enteric nervous system activity generates contractile patterns prior to maturation of gastrointestinal motility

open access: yesNeurogastroenterology &Motility, EarlyView.
Spontaneous neuronal network activity is critical for circuit maturation, yet whether this is a feature of enteric nervous system development has yet to be established. Here, we identify clustered ripples, a previously undescribed form of neurogenic gastrointestinal motility that shares many features with spontaneous neuronal networks in other systems.
Lori B. Dershowitz   +4 more
wiley   +1 more source

Discrepancies Between Recommendations in Evidence‐Based Guidelines for the Management of Obesity in Adolescents and Adults: An Evidence Map

open access: yesObesity Reviews, EarlyView.
ABSTRACT Background/Aim The aim of this evidence map is to provide a systematic overview of evidence‐based guidelines for the management of obesity and to highlight discrepancies between recommendations for the pediatric and adult populations. Knowing about these discrepancies may be relevant during the transition from pediatrics to adult healthcare to
Jana Brauchmann   +13 more
wiley   +1 more source

Contemporary Concise Review 2024: Chronic Obstructive Pulmonary Disease

open access: yesRespirology, EarlyView.
SUMMARY OF KEY POINTS Non‐smoking COPD is common in LMICs, especially in women. Biomass fuel and air pollution are major risk factors with distinct pathophysiology. The ‘eosinophilic’ endotype in COPD is biologically distinct from asthma. PRISm, FEV1/FVC Z‐scores, and quantitative CT improve early COPD detection.
Sarita Thawanaphong, Parameswaran Nair
wiley   +1 more source

Manipulation of Chemistry and Biology with Visible Light Using Tetra‐ortho‐Substituted Azobenzenes and Azonium Ions

open access: yesAngewandte Chemie, Volume 137, Issue 24, June 10, 2025.
Tetra‐ortho‐Azobenzenes (TOABs) in broad daylight: in recent years, TOAB photoswitches became indispensable tools for all‐visible‐light manipulation of chemistry, biology and materials. This review explores their unique photochemical properties, design and synthetic approaches, offering support in choosing a TOAB for a given application.
Francesca Cardano   +2 more
wiley   +2 more sources

Thoracic Society of Australia and New Zealand (TSANZ) Guidance for the Management of Electronic Cigarette Use (Vaping) in Adolescents and Adults

open access: yesRespirology, EarlyView.
ABSTRACT Electronic cigarette (EC) use, especially among younger members of society, has grown to concerning levels in many countries, including Australia and New Zealand. Uptake in the general population, driven by technological and pharmacological innovations, and accelerated by aggressive tobacco/vaping industry marketing, has outpaced medical ...
Henry Marshall   +13 more
wiley   +1 more source

Characterization of ibogaine analogs on the hα3β4 nicotinic acetylcholine receptor. [PDF]

open access: yes, 2012
Nicotine addiction is a global health problem that affects nearly one-third of the population. Animal models have shown that the beta-4 subunit of nicotinic acetylcholine receptors (nAChR) expressed in the habenulointerpeduncular pathway plays a ...
Ross, Jordan
core  

Structural mechanism of muscle nicotinic receptor desensitization and block by curare

open access: yesNature Structural & Molecular Biology, 2022
Md Mahfuzur Rahman   +6 more
semanticscholar   +1 more source

Myths and methodologies: Invasive and non‐invasive assessment of respiratory muscle activity in humans

open access: yesExperimental Physiology, EarlyView.
Abstract Survival relies on neural respiratory drive from the medullary respiratory centres to activate the respiratory muscles for breathing. Accurate assessment of respiratory muscle activity, as an estimate of neural respiratory drive in humans, will facilitate a greater understanding of respiratory physiology, the pathophysiology of diseases and ...
Anna L. Hudson   +3 more
wiley   +1 more source

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