The effects of Nicotine on licking behavior induced by Apomorphine in rats
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 1999 Objective: The purpose of the present study was to determine the possible interaction of nicotine or muscarinic receptor mechanism(s) with the licking behavior induced by apomorphine in rats.
MR Zarrindast, M Shecharchi, M Rezayat
doaj
Untangling direct and domain-mediated interactions between nicotinic acetylcholine receptors in DHA-rich membranes [PDF]
arXiv, 2019 At the neuromuscular junction (NMJ), the nicotinic acetylcholine receptor (nAChR) self-associates to give rise to rapid muscle movement. While lipid domains have maintained nAChR aggregates in-vitro, their specific roles in nAChR clustering are currently unknown. In the present study, we carried out coarse-grained molecular dynamics simulations (CG-MD)
arxiv
Experimental Physiology, EarlyView.Abstract Doppler ultrasound may be used to assess leg blood flow (Q̇leg${{\dot{Q}}_{{\mathrm{leg}}}}$), but the reliability of this method remains unexplored in patients with chronic obstructive pulmonary disease (COPD), where between‐subject variability may be larger than healthy due to peripheral vascular changes.
Milan Mohammad +5 more
wiley +1 more source
Varenicline in the treatment of tobacco dependence
Neuropsychiatric Disease and Treatment, 2008 Karl Fagerström1, John Hughes21Smokers Information Centre, Fagerström Consulting AB, Berga Alle 1, 25452 Helsingborg, Sweden; 2University of Vermont, Burlington, Vermont, USAAbstract: Varenicline, a partial agonist of α4& ...
Karl Fagerström, John Hughes
doaj
Chemical modification of epibatidine causes a switch from agonist to antagonist and modifies its selectivity for neuronal nicotinic acetylcholine receptors [PDF]
, 2000 Jörg E Spang +5 more
openalex +1 more source
Anthelmintic Resistance in Ancylostoma caninum: A Comprehensive Review
Veterinary Medicine and Science, Volume 11, Issue 4, July 2025.This review summarizes the emergence of anthelmintic resistance in Ancylostoma caninum, with a focus on drug classes affected, global prevalence and resistance mechanisms. Early detection and integrated control strategies are essential to combat its spread.
Hande İrem Sönmez +3 more
wiley +1 more source
Unsettling the Hegemony of Intention: Agonistic Image Generation [PDF]
arXivCurrent image generation paradigms prioritize actualizing user intention - "see what you intend" - but often neglect the sociopolitical dimensions of this process. However, it is increasingly evident that image generation is political, contributing to broader social struggles over visual meaning.
arxiv
Cholinergic Modulation of Locomotion and Striatal Dopamine Release Is Mediated by α6α4* Nicotinic Acetylcholine Receptors [PDF]
, 2010 Dopamine (DA) release in striatum is governed by firing rates of midbrain DA neurons, striatal cholinergic tone, and nicotinic ACh receptors (nAChRs) on DA presynaptic terminals.
Drenan, Ryan M. +8 more
core
Binding Properties of Agonists and Antagonists to Distinct Allosteric States of the Nicotinic Acetylcholine Receptor Are Incompatible with a Concerted Model [PDF]
, 2000 M. Krauß +3 more
openalex +1 more source
British Journal of Pharmacology, Volume 182, Issue 13, Page 2997-3016, July 2025.Abstract Background and Purpose Preclinical studies suggest that highly selective dopamine D3 receptor (D3R) antagonists or partial agonists hold promise for treating substance use disorders. However, their limited effectiveness in reducing cocaine self‐administration is a major drawback.
Omar Soler‐Cedeño +9 more
wiley +1 more source