The autonomic nervous system: Time for a conceptual reframing?
The Journal of Physiology, EarlyView.Abstract figure legend The sympathetic, parasympathetic and enteric branches of the autonomic nervous system (ANS) are considered separate entities in the current model of the nervous system (A). We propose a simpler model that avoids the use of the term ‘the autonomic nervous system’ (B).
Alexandru C. Barboi +1 more
wiley +1 more source
Invariant Aspartic Acid in Muscle Nicotinic Receptor Contributes Selectively to the Kinetics of Agonist Binding [PDF]
, 2004 Won Yong Lee, Steven M. Sine
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Dual cholinergic and serotonergic excitatory pathways mediate oxygen sensing in the zebrafish gill
The Journal of Physiology, EarlyView.Abstract figure legend The present study identified two sub‐populations of gill oxygen sensing neuroepithelial cells (NECs) distinguishable by their stored neurotransmitters – serotonin (5‐hydroxytryptamine, 5‐HT) or acetylcholine (ACh). Using transgenic Tg(elavl3:GCaMP6s) zebrafish, which express an endogenous calcium reporter in neurons, we ...
Maddison Reed +3 more
wiley +1 more source
Ex vivo receptor occupation of GTS-21, a novel nicotinic receptor agonist, in rats.
, 1996 Yoshihisa Nozawa +4 more
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The characterization of a novel rigid nicotine analog with α7-selective nAChR agonist activity and modulation of agonist properties by boron inclusion [PDF]
, 2005 Roger L. Papke +4 more
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Modulation of airway inflammation and resistance in mice by a nicotinic receptor agonist [PDF]
, 2005 M-R. Blanchet +2 more
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Drug‐Related Engrams and Their Role in the Persistence and Recurrence of Drug‐Related Behaviors
Hippocampus, Volume 35, Issue 6, November 2025.ABSTRACT Memory is a cornerstone of human behavior, and addiction offers a compelling model of its persistence and plasticity. The scope of engram research has rapidly expanded to include addiction‐related phenomena. Addiction‐related memories, like strong aversive memories, are often highly resistant to extinction and can continue to drive relapse ...
M. Cutler, A. Thati, S. L. Grella
wiley +1 more source
Cannabinoid CB2 receptor‐mediated analgesia: mechanism‐based insights and therapeutic potential
British Journal of Pharmacology, Volume 182, Issue 21, Page 5090-5118, November 2025.Agonists of the cannabinoid 2 (CB2) receptor have shown promise for the treatment of pain in a variety of animal models. However, despite current preclinical evidence supporting the use of CB2 agonists for pain, successful translation of findings from preclinical models to human patients is lacking.
Kelsey G. Guenther, Andrea G. Hohmann
wiley +1 more source