Entering new chemical space with isolable complexes of single, zero-valent silicon and germanium atoms [PDF]
, 2021 Monatomic zero-valent silicon and germanium complexes (silylones and germylones), stabilised by neutral donating ligands, emerged only recently as a new class of low-valent group 14 element compounds.
Drieß, Matthias +3 more
core +1 more source
Two New closo- or nido-Carborane Diphosphine Complexes: Synthesis, Characterization and Crystal Structures [PDF]
Bulletin of the Korean Chemical Society, 2011 Two new carborane complexes containing closo- or nido-carborane diphosphine ligands with the formula: complex (1) and (2) have been synthesized and characterized by elemental analysis, 1H and 13C NMR spectroscopy and X-ray structure determination. The X-ray structure analyses revealed that the carborane diphosphine ligand was degraded from closo-1,2 ...
Lingqian Kong +4 more
openaire +1 more source
Medicinal Chemistry of Boron-Bearing Compounds for BNCT- Glioma Treatment: Current Challenges and Perspectives [PDF]
, 2018 Since its first description, boron neutron capture therapy (BNCT) was a special type of radiotherapy for treatment of cancer and with focus mainly on glioma therapeutic.
Cerecetto, Hugo, Couto, Marcos
core +2 more sources
The Far Side of Carboranes: Anticancer Active Monocations and Ambiently Stable Dications
Angewandte Chemie International Edition, EarlyView.This work describes the synthesis of bench‐stable dicationic carboranes. Their enhanced electrophilicity is documented by opening the clusters with weak nucleophiles or dihydrogen. The surprising stability of positively charged carboranes in water enabled a study of their in vitro antiproliferative activity, which surpassed the effects of doxorubicin ...
Vlastimil Němec +10 more
wiley +1 more source
NITRILIUM DERIVATES OF NIDO-CARBORANE IN SYNTHESIS OF TRANSITIONAL METAL COMPLEXES [PDF]
, 2023 This work was supported by Russian Science Foundation, project № 21-73 ...
Anufriev, S. A. +3 more
core
Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents
Chemistry – A European Journal, EarlyView.This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley +1 more source
Tethered N-Heterocyclic Carbene-Carboranes: Unique Ligands that Exhibit Unprecedented and Versatile Coordination Modes at Rhodium [PDF]
, 2016 Four brand new hybrid ligands combining an N-heterocyclic carbene tethered with two isomeric nido-dicarbaundecaborane dianions, a neutral closo-dicarbadodecaborane or a closo-dicarbadodecaborane anion are described.
Fox, MA +3 more
core +3 more sources
Cationic Polyhedral Chalcogenaboranes: Activation without breaking Wade's Rules
Angewandte Chemie, Volume 137, Issue 10, March 3, 2025.The paper presents the first cationic chalcogenaboranes having the same skeletal electron pair count as their neutral precursors but bearing a positive charge. This is in contrast with Wade's rules, which claim that a change in the shape or number of skeletal electron pairs is inevitable. The enhanced electrophilicity of these compounds is demonstrated
Josef Holub +8 more
wiley +2 more sources
Carboranyl Derivatives of Rofecoxib with Cytostatic Activity against Human Melanoma and Colon Cancer Cells. [PDF]
, 2020 Owing to the involvement of cyclooxygenase-2 (COX-2) in carcinogenesis, COX-2-selective inhibitors are increasingly studied for their potential cytotoxic properties. Moreover, the incorporation of carboranes in structures of established anti-inflammatory
Buzharevski, Antonio +10 more
core +1 more source
Medicinal Research Reviews, Volume 46, Issue 1, Page 203-237, January 2026.ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller +5 more
wiley +1 more source