Carboranes as unique pharmacophores in antitumor medicinal chemistry
Carborane is a carbon-boron molecular cluster that can be viewed as a 3D analog of benzene. It features special physical and chemical properties, and thus has the potential to serve as a new type of pharmacophore for drug design and discovery.
Yu Chen +10 more
doaj +1 more source
Crystal Structure of 9-Dibenzylsulfide-7,8-dicarba-nido-undecaborane 9-Bn2S-7,8-C2B9H11
The crystal structure of 9-dibenzylsulfide-7,8-dicarba-nido-undecaborane 9-Bn2S-7,8-C2B9H11 was determined by a single-crystal X-ray diffraction. One of the benzyl groups is located above the open face of the carborane cage with a short H···H distance (2.
Sergey A. Anufriev +3 more
doaj +1 more source
Blue Phosphorescent Zwitterionic Iridium(III) Complexes Featuring Weakly Coordinating nido-Carborane-Based Ligands [PDF]
We report the development of a new class of phosphorescent zwitterionic bis(heteroleptic) Ir(III) compounds containing pyridyl ligands with weakly coordinating nido-carboranyl substituents.
Peter I. Djurovich (1494643) +8 more
core +3 more sources
Water-soluble BODIPY-nido-carborane nanoparticles applied to biocompatibility tumor cell imaging [PDF]
In this article, o-carborane has a high boron content, high hydrophobicity, and good chemical stability. It has been widely used in the fields of biology and medicine, especially in the application of boron neutron capture therapy (BNCT). However, o-carborane is a fat-soluble compound, its hydrophobicity is too strong, and its bioavailability is poor ...
Dongfang, Dai +4 more
openaire +2 more sources
Synthesis and Delayed Fluorescent Properties of p-Nido-Carborane-Triarylborane Conjugates with a Methyl-Substituted Phenylene Linker [PDF]
A series of p?nido?carborane?triarylborane conjugates (nido?1?3) in which a methyl group is introduced at the ortho?position to the carborane cage in the phenylene linker was prepared and characterized. All compounds exhibit broad low?energy absorptions (
쿠투마타라 수렌드란 수지트 +1 more
core +1 more source
New Aspects of Ruthenium-Mediated Polyhedral Contraction of Monocarbollides
It has been shown that the interaction of tris(triphenylphosphine)ruthenium dichloride RuCl2(PPh3)3 (1) with 10-vertex monocarborane [6-Ph-nido-6-CB9H11]−[Et4N]+ (2) under mild thermolysis conditions is not selective due to the undesired coordination of ...
Dmitry A. Loginov +3 more
doaj +1 more source
Palladium-Catalyzed Amination of 2-Iodo-para-carborane [PDF]
The palladium-catalyzed Buchwald−Hartwig amination of B-iodocarborane by various azoles and amines is described for the first time. The reactions of 2-iodo-p-carborane with indole, imidazole, benzimidazole, or carbazole in the system Pd(dba)2−BINAP ...
Vladimir I. Bregadze (1978285) +6 more
core +7 more sources
Cyclic Voltammetry Study of Closo-Ruthenacarboranes
Electrochemical properties of transition metal complexes are important parameters that should be considered for the successful application of these compounds in catalytic reactions.
Ivan D. Grishin +2 more
doaj +1 more source
Zwitterionic nido-Carborane-Fused Phospholes [PDF]
Using readily available and easy-to-handle reagents, a novel type of nido-carborane-fused phosphole was obtained from a simple procedure. Its crystallographic structure was determined, and DFT calculations have been performed, unraveling the key ...
Guanyu Tao (4788930) +2 more
core +1 more source
Bis(carboranyl)amides 1,1′-μ-(CH2NH(O)C(CH2)n-1,2-C2B10H11)2 (n = 0, 1) were prepared by the reactions of the corresponding carboranyl acyl chlorides with ethylenediamine.
Yasunobu Asawa +7 more
doaj +1 more source

