Results 41 to 50 of about 206,217 (225)
OncoImmunology, 2022 The immune system is recognized as an important factor in regulating the development, progression, and metastasis of cancer. Myeloid-derived suppressor cells (MDSCs) are a major immune-suppressive cell type by interfering with T cell activation ...
Takuya Kato +9 more
doaj +1 more source
View, 2022 Among modalities of cancer immunotherapy, near‐infrared photoimmunotherapy (NIR‐PIT) has reached significant preclinical and clinical stages and quickly evolved over the last 5 years.
Hailey Monaco +3 more
doaj +1 more source
Trastuzumab‐based near‐infrared photoimmunotherapy in xenograft mouse of breast cancer
Cancer Medicine, 2023 Near‐infrared photoimmunotherapy (NIR‐PIT) is a novel form of cancer treatment using conjugates of antibody against overexpressed antigens in cancers and photoabsorber IRDye700DX.
Susumu Yamashita +4 more
doaj +1 more source
, 2022 Zunehmend individuelle Kundenwünsche, schwankende Auftragsmengen und hohe Effizienzanforderungen verursachen besonders bei kleinen und mittleren Unternehmen einen hohen Aufwand.
core +1 more source
Wound healing after excision of subcutaneous tumors treated with near‐infrared photoimmunotherapy
Cancer Medicine, 2020 Near‐infrared photoimmunotherapy (NIR‐PIT) is a novel cancer therapy that employs a combination of infrared light and tumor‐targeted monoclonal antibody‐photoabsorber conjugates to cause both direct tumor necrosis and immunogenic cell death.
Adrian Rosenberg +7 more
doaj +1 more source
Improved micro-distribution of antibody-photon absorber conjugates after initial near infrared photoimmunotherapy (NIR-PIT) [PDF]
Journal of Controlled Release, 2016 Near infrared photoimmunotherapy (NIR-PIT), a targeted cancer therapy which uses an antibody-photo absorber conjugate (APC) and near infrared light exposure, dramatically improves nano-drug delivery into treated tumor beds due to enhanced vascular permeability.
Tadanobu, Nagaya +5 more
openaire +2 more sources
In vivo effect of NIR-PIT for MDAMB468 tumor (one shot NIR-PIT).
, 2015 (A) NIR-PIT regimen. Fluorescence images were obtained at each time point as indicated. (B) In vivo fluorescence real-time imaging of tumor bearing mice in response to NIR-PIT.
Yuko Nakamura (645668) +5 more
core +1 more source
In vivo effect of NIR-PIT for MDAMB468 tumor (“three split” NIR-PIT).
, 2015 (A) NIR-PIT regimen. (B) Tumor growth was significantly inhibited in the NIR-PIT treatment groups (n = 10–13, **p < 0.001 vs other groups, Bonferroni’s test with ANOVA). (C) Significantly prolonged survival was observed in the APC i.v. only group and NIR-
Yuko Nakamura (645668) +5 more
core +1 more source
Near-infrared photoimmunotherapy for osteosarcoma targeting epidermal growth factor receptor
Translational OncologyOsteosarcoma is the most common bone tumor, and it possesses high metastatic propensity. Although systemic chemotherapy has improved its prognosis, improvements in survival rates have stalled in recent years.
Motofumi Suzuki +2 more
doaj +1 more source
Advanced Functional Materials, EarlyView.A dynamically actuated reconfigurable topographical surface (DARTS) integrates contact‐mediated bactericidal nanotopography with programmable mechanical actuation to actively disrupt bacterial biofilms. Dynamic surface reconfiguration enhances bacterial killing and suppresses implant‐associated infections in vivo, providing a new strategy for active ...
Mohammad Asadi Tokmedash +4 more
wiley +1 more source