Results 21 to 30 of about 206,217 (225)

NIR-PIT: Will it become a standard cancer treatment? [PDF]

Front Oncol, 2022
Furusawa A, Choyke PL, Kobayashi H.
europepmc   +4 more sources

Human epidermal growth factor receptor 3-targeted near-infrared photoimmunotherapy in a xenograft mouse model of breast cancer [PDF]

BMC Cancer
Background Human epidermal growth factor receptor 3 (HER3), a member of the HER/ErbB family, is broadly expressed across major breast cancer subtypes and contributes to tumor initiation, progression, and therapy resistance.
Makoto Kano, Aki Furusawa, Hiroshi Fukushima, Seiichiro Takao, Shuhei Okuyama, Hiroshi Yamamoto, Motofumi Suzuki, Ko Kitamura, Miyu Kano, Peter L Choyke, Hisataka Kobayashi   +10 more
doaj   +2 more sources

Avoiding thermal injury during near-infrared photoimmunotherapy (NIR-PIT): the importance of NIR light power density. [PDF]

Oncotarget, 2017
Near-infrared photoimmunotherapy (NIR-PIT) is a newly-established cancer treatment which employs the combination of an antibody-photoabsorber conjugate (APC) and NIR light. When NIR light is absorbed by APC-bound tissues, a certain amount of heat is generated locally.
Okuyama S, Nagaya T, Ogata F, Maruoka Y, Sato K, Nakamura Y, Choyke PL, Kobayashi H.   +7 more
europepmc   +4 more sources

Development of a Peptide-Based Photoimmunotherapy Drug Targeting PD-L1 [PDF]

Molecules
Near-infrared photoimmunotherapy (NIR-PIT) has recently attracted attention as a highly selective cancer treatment, with good treatment outcomes observed from the only antibody-based drug currently available for clinical use. However, since only a single
Takuya Otani, Naoya Kondo, Ayaka Kanai, Hirofumi Hanaoka   +3 more
doaj   +2 more sources

Therapeutic potential of photoimmunotherapy in solid tumors expressing CD98 heavy chain [PDF]

Scientific Reports
Near-infrared photoimmunotherapy (NIR-PIT) is an emerging targeted cancer therapy that uses an antibody–photoabsorber conjugate. In this study, we evaluated the therapeutic potential of NIR-PIT targeting CD98 heavy chain (CD98hc), a transmembrane ...
Citra R. A. P. Palangka, Naoya Kondo, Ayaka Kanai, Hirofumi Hanaoka   +3 more
doaj   +2 more sources

Opening up new VISTAs: V-domain immunoglobulin suppressor of T cell activation (VISTA) targeted near-infrared photoimmunotherapy (NIR-PIT) for enhancing host immunity against cancers [PDF]

Cancer Immunology, Immunotherapy, 2022
Hiroaki Wakiyama, Aki Furusawa, Fuyuki Inagaki   +2 more
exaly   +2 more sources

Response to Letter regarding EpCAM-targeted near-infrared photoimmunotherapy (NIR-PIT) for the treatment of breast cancer. [PDF]

Ann Med
Furusawa A, Kobayashi H.
europepmc   +3 more sources

Adding Intratumoral Antibody-Photoabsorber Conjugate Improves Efficacy of Near-Infrared Photoimmunotherapy (NIR-PIT). [PDF]

Cancer Sci
Near‐infrared photoimmunotherapy (NIR‐PIT) is a new type of cancer treatment that specifically kills target cells while sparing normal tissue. This treatment induces cancer cell death by activating a photoreactive dye with near‐infrared light in an ...
Kano M, Furusawa A, Takao S, Kano M, Suzuki M, Yamamoto H, Okuyama S, Kitamura K, Choyke PL, Kobayashi H.   +9 more
europepmc   +3 more sources

Computer-aided optimal open pit design with variable slope angles [PDF]

, 1999
The use of open pit mining has increased to extract large and low grade deposits with the growth in demand for raw materials, with the advances in mining technology and with the depletion of high grade and readily accessible orebodies.
Khalokakaie, Reza
core   +6 more sources

Preserved host immunity with intercellular adhesion molecule-1 (ICAM-1)-targeted near-infrared photoimmunotherapy (NIR-PIT) in the treatment of triple-negative breast cancer and other malignancies [PDF]

Cancer Letters
Aki Furusawa, Seiichiro Takao, Motofumi Suzuki   +2 more
exaly   +2 more sources