Results 211 to 220 of about 16,229 (264)

Mutations in nirA Gene of Aspergillus nidulans and Nitrogen Metabolism

Nature, 1978
IN both prokaryotes and eukaryotes many structural genes are subject to more than one form of control. The ways in which these various forms of regulation interact with each other are therefore of considerable importance for an understanding of the control of gene expression.
H N Arst
exaly   +3 more sources

Phase 3 MAGNITUDE study: First results of niraparib (NIRA) with abiraterone acetate and prednisone (AAP) as first-line therapy in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) with and without homologous recombination repair (HRR) gene alterations.

Journal of Clinical Oncology, 2022
12 Background: Approximately 20% of mCRPC has alterations in genes associated with HRR and is responsive to PARP inhibitors (PARPi) such as NIRA. Combined PARPi with androgen receptor pathway targeting may also benefit unselected mCRPC.
K. Chi, D. Rathkopf, M. Smith, E. Efstathiou, G. Attard, D. Olmos, J. Lee, E. Small, A. J. Gomes, G. Roubaud, M. Saad, B. Żurawski, V. Sakalo, G. Mason, A. del Corral, George C. Wang, Daphne Wu, B. Diorio, A. Lopez-Gitlitz, S. Sandhu   +19 more
semanticscholar   +1 more source

Reversal of Cisplatin Resistance in Ovarian Cancer by the Multitargeted Nanodrug Delivery System Tf-Mn-MOF@Nira@CDDP.

ACS Applied Materials and Interfaces, 2023
Cisplatin (CDDP) is a widely used chemotherapeutic drug with proven efficacy for treating tumors. However, its use has been associated with severe side effects and eventually leads to drug resistance, thus limiting its clinical application in patients ...
Yuan Liu, Yiru Wang, X. Guan, Qiong Wu, Meng-Jun Zhang, Ping Cui, Can-Fei Wang, Xiu-Wei Chen, Xian-Wei Meng, Teng-Chuang Ma   +9 more
semanticscholar   +1 more source

Nira

ACM SIGGRAPH 2019 Appy Hour, 2019
Nira is an asset review and collaboration platform capable of rendering massive 3D production files in real time for interactive web-based viewing on any device, including lower-powered mobile smartphones and tablets. Nira achieves this by employing a custom server-side asset ingestion pipeline, a custom server-side real time renderer, a collection of ...
Arash Keissami, Andrew Johnson, Dario Manesku   +2 more
openaire   +1 more source

Niraparib (NIRA) with abiraterone acetate and prednisone (AAP) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) and homologous recombination repair (HRR) gene alterations: Second interim analysis (IA2) of MAGNITUDE.

Journal of Clinical Oncology, 2023
170 Background: In the primary analysis of the phase 3 MAGNITUDE study, NIRA/AAP significantly improved outcomes in pts with mCRPC and HRR gene alterations. Here, we report results from IA2 of secondary endpoints in MAGNITUDE.
E. Efstathiou, M. Smith, S. Sandhu, G. Attard, M. Saad, D. Olmos, E. Castro, G. Roubaud, Andrea Juliana Gomes, E. Small, D. Rathkopf, H. Gurney, W. Jung, G. Mason, Peter St. John Francis, George C. Wang, Daphne Wu, B. Diorio, A. Lopez-Gitlitz, K. Chi   +19 more
semanticscholar   +1 more source

Project nira

ACM SIGGRAPH 2019 Real-Time Live!, 2019
Here is some text in the style of last year's RTL lineup descriptions: We demonstrate a collaboration platform for viewing massive 3D assets in real-time using any web browser on any device. Technologies such as high framerate server-side rendering, low-latency video encoding, and artist friendly markup tools are combined to accelerate production ...
Arash Keissami, Andrew Johnson, Dario Manesku   +2 more
openaire   +1 more source

NIRA

Proceedings of the ACM SIGCOMM workshop on Future directions in network architecture - FDNA '03, 2003
This paper presents the design of a new Internet routing architecture (NIRA). In today's Internet, users can pick their own ISPs, but once the packets have entered the network, the users have no control over the overall routes their packets take. NIRA aims at providing end users the ability to choose the sequence of Internet service providers a packet ...
openaire   +1 more source

FIRST/ENGOT-OV44: A phase 3 clinical trial of dostarlimab (dost) and niraparib (nira) in first-line (1L) advanced ovarian cancer (aOC).

Journal of Clinical Oncology
LBA5506 Background: The FIRST/ENGOT-OV44 trial evaluated adding dost, a programmed cell death protein-1 inhibitor, to 1L platinum-based chemotherapy (PBCT) and nira maintenance (MT) ± bevacizumab (bev) in patients (pts) with aOC.
A. Hardy-Bessard, E. Pujade-Lauraine, R. Moore, F. Montestruc, A. Redondo, M. Mirza, N. Volodko, T. Ciuleanu, L. Gilbert, R. Eitan, F. Zagouri, S. Pignata, R. Glasspool, Jacobus Pfisterer, R. Phaeton, C. Anderson, M. Rodrigues, F. Musa, I. Ray-Coquard, K. Moore   +19 more
semanticscholar   +1 more source

Penetapan Kadar Mineral Kalsium Air Nira Aren Kabupaten Aceh Besar Secara Kompleksometri

Jurnal Sains dan Kesehatan Darussalam
Air nira aren diketahui memiliki kandungan protein, mineral, dan vitamin. Berbagai mineral penting ditemukan dalam air nira aren seperti Kalium, Kalsium, Fosfor, Besi dan Natrium.
Azmalina Adriani, Rizki Andalia, Hardiana, I. Mustafa   +3 more
semanticscholar   +1 more source

Acceptance of the Waste by ONDRAF/NIRAS

Volume 2: Mgmt. Low/Interm. Level Waste; Spent Fuel; Economics/Analyses for Waste Mgmt.; Radiological Characterization/Application Release Criteria; Panel Sessions; Solid Waste Reduction/Treatment; Current Activities in Central/Eastern Europe; Environmental Remediation Technology; LL/ILW; HLW/Spent Fuel; Chernobyl; D&D Waste; Performance Assessment; MOX and Spent UOX; D&D Nuclear Reactors; Decommissioning of Other Nuclear Facilities, 2001
Abstract One of the tasks of ONDRAF/NIRAS, National Agency for Radioactive Waste and Enriched Fissile Materials, is to manage non-conditioned waste and conditioned waste from the waste producers.
openaire   +1 more source