Results 141 to 150 of about 365,712 (218)

MiR‐146a‐5p Suppresses M1 Polarization of Tumor‐Associated Macrophages via IRAK1/NF‐κB Signaling in Colorectal Polyps

Annals of Gastroenterological Surgery, EarlyView.
MiR‐146a‐5p is downregulated in colorectal polyps, leading to IRAK1 upregulation and NF‐κB activation, which promotes M1 macrophage polarization and inflammation. Overexpression of miR‐146a‐5p suppresses IRAK1/NF‐κB signaling, reduces M1 polarization, and alleviates inflammatory responses.
Peng Song, Lianhui Wu, Huabin Qiu, Lei Luo, Jianzhao Qiu, Shuping Xiao, Jincai He   +6 more
wiley   +1 more source

Network Silsesquioxane-Based Organogel/Silicone Composites for the Long-Lasting Delivery of Nitric Oxide. [PDF]

Molecules
Hallowell KD, Naser Aldine F, Vonder Brink HN, Mockensturm AK, Handa H, Brisbois EJ, Ostrowski AD, Furgal JC.   +7 more
europepmc   +1 more source

Exploratory Analysis of Factors Associated With the Recovery of Erectile Dysfunction After Rectal Cancer Surgery (Sub‐Analysis of LANDMARC Trial)

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Erectile dysfunction (ErD) is an important complication after rectal cancer surgery, however a substantial proportion of patients experience functional recovery over time. Evidence regarding which patients are more likely to recover remains limited.
Ryosuke Mizuno, Koya Hida, Masakatsu Numata, Takashi Sakamoto, Kazutaka Obama, Akio Shiomi, Ryo Inada, Manabu Shiozawa, Mayumi Ozawa, Masanori Hotchi, Daisuke Yamamoto, Suguru Hasegawa, Masashi Miguchi, Shinobu Ohnuma, Tomohiro Yamaguchi, Tomonori Akagi, Yusuke Kinugasa, Shigeki Yamaguchi, Hiroyasu Kagawa, Masahiko Watanabe, Takeshi Naitoh, Ichiro Takemasa   +21 more
wiley   +1 more source

A Case of Multiple Mitochondrial Dysfunctions Syndrome 1 and Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Multiple mitochondrial dysfunctions syndrome 1 (MMDS1, MIM #605711) due to NFU1 gene defects is an ultra‐rare autosomal recessive inborn error of metabolism associated with reduced function of NFU1 iron–sulfur cluster (ISC) scaffold protein.
Charles R. DiFalco, Aaron Williams, Claudia Soler‐Alfonso, Emily Waskow, Elizabeth Mizerik, Fernando Scaglia, Chaya N. Murali   +6 more
wiley   +1 more source

Engineering a dual-action nitric oxide and propolis releasing polymeric matrix for extended antimicrobial efficacy.

J Mater Chem B
Sapkota A, Schell S, Popoola MO, Handa H, Brisbois EJ.   +4 more
europepmc   +1 more source

Life-Course Regulation of Health and Disease by Nitric Oxide: Mechanistic Insights. [PDF]

Antioxidants (Basel)
Hsu CN, Tain YL.
europepmc   +1 more source

Extent of Sinus Surgery Is Associated With Disease Control in Biologic Treated Type 2 Dominant CRS

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background A greater benefit of biologics is observed after surgery in Type 2 chronic rhinosinusitis with nasal polyps (CRSwNP). However, the extent of surgery remains undefined in many studies. This study evaluated the extent of surgery on disease control in patients receiving biologics for refractory Type 2 dominant CRSwNP.
Nicholas J. Campion, Peta‐Lee Sacks, Lu Hui Png, Ruoxin Hua, Rhea Darbari Kaul, Raquel Alvarado, Christine Choy, Raymond Sacks, Peter Earls, Raewyn G. Campbell, Larry Kalish, Richard J. Harvey   +11 more
wiley   +1 more source

Nitric Oxide and Hydrogen Sulfide Crosstalk in Plants: Redox Regulation, Stress Adaptation, and Emerging Applications. [PDF]

Int J Mol Sci
Dos Reis RA, Seabra AB, Aragão CB, Halfeld M, Nunes RS, Rodriguez R, Benavides-Mendoza A, Rubilar O, Tortella GR.   +8 more
europepmc   +1 more source

Female‐Specific Risk of TAS2R Variants in Chronic Rhinosinusitis: A Hospital‐Based Cohort Study From the Taiwan Precision Medicine Initiative

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Bitter taste receptors (T2Rs) function in the innate immune defense of the sinonasal mucosa; however, the genetic association between the TAS2R gene family and chronic rhinosinusitis (CRS) remains understudied in Asian populations.
Rong‐San Jiang, Man‐Wei Hua, I‐Chieh Chen, Yi‐Ming Chen, Shun‐Hung Lin, Kuan‐Yu Lai, Yi‐Chen Chen   +6 more
wiley   +1 more source

Breath-by-breath quantification of inhaled nitric oxide absorption and modeling of methemoglobin kinetics. [PDF]

Redox Biol
Dong R, Wanderley HV, Mereto E, Safaee Fakhr B, Nardini R, Yu B, Berra L.   +6 more
europepmc   +1 more source