Results 151 to 160 of about 365,712 (218)

IRF‐1 modulates hepatic ferroptosis and aggravates liver ischemia/reperfusion injury via DYRK1α

Animal Models and Experimental Medicine, EarlyView.
IRF‐1 modulates hepatic ferroptosis and aggravates liver ischemia/reperfusion injury via DYRK1α. Abstract Background The purpose is to define the contribution of the interferon regulatory factor‐1–dual‐specificity tyrosine phosphorylation‐regulated kinase 1α (IRF‐1–DYRK1α) axis to hepatocellular ferroptosis during liver ischemia/reperfusion injury ...
Jinping Zhang, Jinming Zhang, Siyuan Song, Mingyang Li, Liying Sun, Zhijun Zhu, Dongdong Lin   +6 more
wiley   +1 more source

Strategies for inducing diabetes in laboratory animals: Advances from chemical, surgical, immunologic, dietary, and genetic approaches

Animal Models and Experimental Medicine, EarlyView.
This review summarizes the principal experimental approaches used to induce diabetes in animal models. Strategies include chemical agents (streptozotocin, alloxan, dithizone, gold thioglucose), dietary interventions (high‐fat and high‐sugar diets), surgical methods (total or partial pancreatectomy), genetic models (db/db, ob/ob, Goto‐Kakizaki [GK ...
Milad Faraji, Maedeh Faraji, Nasrin Kazemipour   +2 more
wiley   +1 more source

Successive nitric oxide and lipoic acid priming mitigates [ZnO]NPs toxicity in wheat: experimental and DFT insights. [PDF]

Sci Rep
El Shazoly RM, El Zohary AM, El-Sayed MM, Othman AA, Mohammed AAK, Abdel-Basset R.   +5 more
europepmc   +1 more source

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

Spermidine stimulates hypocrellin A biosynthesis through nitric oxide signaling in Shiraia sp. S9. [PDF]

Bioresour Bioprocess
Zheng LP, Cong RP, Li XP, Zhou JQ, Wang JW.   +4 more
europepmc   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Closed-Loop Synergistic Nitric Oxide/Hydrogen Delivery with Feedback Control for Diabetic Wound Healing. [PDF]

Nanomicro Lett
Wen P, Luo P, Gao F, Yang M, Li J, Yang Z.   +5 more
europepmc   +1 more source

Carbon‐Confined Fe3C/Fe3N Janus Interfaces for Selective Nitric Oxide‐to‐Ammonia Electroreduction

Angewandte Chemie, EarlyView.
A defect‐rich, graphitic‐carbon‐confined Fe3C/Fe3N Janus catalyst integrates NO transport, adsorption/activation, and interfacial H supply for efficient nitric oxide electroreduction to ammonia. Built from earth‐abundant elements, this architecture enables high‐yield and high‐efficiency NH3 synthesis while valorizing industrial NO emissions.
Jialing Song, Ziqi Wei, Haotian Huang, Lupeng Han, Biyi Huang, Evangelina Pensa, Sam Fong Yau Li, Eslam Hamed, Fun Man Fung, Emiliano Cortés, Dengsong Zhang   +10 more
wiley   +1 more source

Water‐Derived Radical Species Initiate Six‐Electron Oxidation of Cyclic Ketones in Microdroplets

Angewandte Chemie, EarlyView.
Spontaneous six‐electron oxidation of cyclic ketones to yield dicarboxylic acids/keto acids is achieved in ethanol microdroplets containing about 2% water under ambient conditions without any metal salts, acids, or oxidants. Mechanistic studies show that trace amounts of water and molecular oxygen serve as active oxidants in this transformation ...
Muhammad Mujahid Ali, Manish Jana, William LeFever, Robert Graham Cooks   +3 more
wiley   +1 more source

Does inhaled nitric oxide treatment of pulmonary hypertension in extremely premature infants improve patient outcomes? [PDF]

J Perinatol
King TL, McNamara PJ, Bischoff AR.
europepmc   +1 more source