Results 231 to 240 of about 508,056 (310)

Exogenous arginine differentially regulates inflammatory cytokine and inducible nitric oxide synthase expression in macrophages. [PDF]

Immunohorizons
Stayer K, Pathan S, Biswas A, Li H, Zhu Y, Lam FW, Marini J, Thevananther S.   +7 more
europepmc   +1 more source

Precise delineation of radiation targets for thoracic tumors in the immunotherapy era: from immune mechanisms to clinical practice

Precision Radiation Oncology, EarlyView.
RT‐immunotherapy synergy for thoracic tumors relies on precise target delineation to protect immune components. IFI, reduced volumes, and optimized positioning minimize damage, while multimodal imaging, DL, PBT, and FLASH‐RT enhance control. These innovations shift RT to an immune‐centric model, improving lung and esophageal cancer outcomes.
Xiaoying Chen, Minxiao Yi, Yu Deng, Qian Shen   +3 more
wiley   +1 more source

RETRACTION: Arctigenin, a Potent Ingredient of Arctium lappa L., Induces Endothelial Nitric Oxide Synthase and Attenuates Subarachnoid Hemorrhage-Induced Vasospasm through PI3K/Akt Pathway in a Rat Model. [PDF]

Biomed Res Int
Research International B.
europepmc   +1 more source

Truncated pyridinylbenzylamines: Potent, selective, and highly membrane permeable inhibitors of human neuronal nitric oxide synthase. [PDF]

Bioorg Med Chem
Vasu D, Do HT, Li H, Hardy CD, Poulos TL, Silverman RB.   +5 more
europepmc   +1 more source

A Novel Approach for the Synthesis of Peripherally Acting Dual Target Inhibitor of Cannabinoid-1 (CB1 Receptor) and Inducible Nitric Oxide Synthase (iNOS) (<i>S</i>-MRI-1867/Zevaquenabant). [PDF]

Molecules
Iyer MR.
europepmc   +1 more source

A Tetrahydrobiopterin-Displacing Potent Neuronal Nitric Oxide Synthase Inhibitor with an Unprecedented Binding Mode. [PDF]

ACS Med Chem Lett
Weerawarna PM, Li H, Rathnayake AD, Hardy CD, Poulos TL, Silverman RB.   +5 more
europepmc   +1 more source

Association of Endothelial Nitric Oxide Synthase Polymorphisms with Clinical Severity in Patients with COVID-19. [PDF]

J Clin Med
İdikut A, Değer İ, Göktaş G, Karahan S, Sarınç S, Köksal D, Babaoğlu MO, Babaoğlu E.   +7 more
europepmc   +1 more source

Inducible nitric oxide synthase (iNOS): More than an inducible enzyme? Rethinking the classification of NOS isoforms. [PDF]

Pharmacol Res
Farahani A, Farahani A, Kashfi K, Ghasemi A.   +3 more
europepmc   +1 more source

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Immunobiology of Nitric Oxide and Regulation of Inducible Nitric Oxide Synthase.

Results and problems in cell differentiation, 2017
Nitric oxide (NO) is a bioactive gas that has multiple roles in innate and adaptive immune responses. In macrophages, nitric oxide is produced by inducible nitric oxide synthase upon microbial and cytokine stimulation. It is needed for host defense against pathogens and for immune regulation.
Martin Lee, Kevin Rey, Katrina J. Besler, Christine Wang, J. Choy   +4 more
semanticscholar   +3 more sources

Multimodality imaging of nitric oxide and nitric oxide synthases

Free Radical Biology and Medicine, 2009
Nitric oxide (NO) and NO synthases (NOSs) are crucial factors in many pathophysiological processes such as inflammation, vascular/neurological function, and many types of cancer. Noninvasive imaging of NO or NOS can provide new insights in understanding these diseases and facilitate the development of novel therapeutic strategies.
Hao, Hong, Jiangtao, Sun, Weibo, Cai
openaire   +2 more sources