Results 1 to 10 of about 120,862 (337)

Room Temperature Reduction of Titanium Tetrachloride-Activated Nitriles to Primary Amines with Ammonia-Borane

Molecules, 2022
The reduction of a variety of aromatic and aliphatic nitriles, activated by a molar equivalent of titanium tetrachloride, has been achieved at room temperature using ammonia borane as a safe reductant. The corresponding methanamines were isolated in good
P. Veeraraghavan Ramachandran, Abdulkhaliq A. Alawaed   +1 more
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A Proterozoic microbial origin of extant cyanide-hydrolyzing enzyme diversity

Frontiers in Microbiology, 2023
In addition to its role as a toxic environmental contaminant, cyanide has been hypothesized to play a key role in prebiotic chemistry and early biogeochemical evolution.
Sarah L. Schwartz, Sarah L. Schwartz, Sarah L. Schwartz, L. Thiberio Rangel, Jack G. Payette, Gregory P. Fournier   +5 more
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Crystal structures of three homologues with increasing ring size: 2-methoxy-4-(thiophen-2-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile, 2-methoxy-4-(thiophen-2-yl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridine-3-carbonitrile and 2-methoxy-4-(thiophen-2-yl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carbonitrile

Acta Crystallographica Section E: Crystallographic Communications, 2023
The title compounds, C15H14N2OS (1a), C16H16N2OS (1b), and C17H18N2OS (1c), form a homologous series in which the size of the saturated ring increases from six- to eight-membered (with four, five and six methylene groups respectively). For 1b and 1c, the
Ali M. S. Hebishy, Galal H. Elgemeie, Lobna M. Gouda, Peter G. Jones   +3 more
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B–N/B–H Transborylation: borane-catalysed nitrile hydroboration

Beilstein Journal of Organic Chemistry, 2022
The reduction of nitriles to primary amines is a useful transformation in organic synthesis, however, it often relies upon stoichiometric reagents or transition-metal catalysis.
Filip Meger, Alexander C. W. Kwok, Franziska Gilch, Dominic R. Willcox, Alex J. Hendy, Kieran Nicholson, Andrew D. Bage, Thomas Langer, Thomas A. Hunt, Stephen P. Thomas   +9 more
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Antifungal Activity of Glucosinolate-Derived Nitriles and Their Synergistic Activity with Glucosinolate-Derived Isothiocyanates Distinguishes Various Taxa of Brassicaceae Endophytes and Soil Fungi

Plants, 2023
The glucosinolates of Brassicaceae plants are converted into bioactive isothiocyanates and other volatiles during a challenge by pathogens and other biotic stressors.
Zsolt Szűcs, Tamás Plaszkó, Eszter Bódor, Hajnalka Csoma, Lajos Ács-Szabó, Attila Kiss-Szikszai, Gábor Vasas, Sándor Gonda   +7 more
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Synthesis, characterization and study of antibacterial activity of some novel tetrazole derivatives

Orbital: The Electronic Journal of Chemistry, 2011
This work aims at synthesizing novel tetrazole derivatives from phenothiazine. Phenothiazine is first converted into corresponding nitrile by reacting it with aldehyde, sodium metabisulphite and sodium cyanide.
Subramaniyan Arulmurugan, Helen P. Kavitha, Bathey R. Venkatraman   +2 more
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Synthesis of Highly Substituted Oxazoles through Iodine(III)-Mediated Reactions of Ketones with Nitriles

Molecules, 2012
In the presence of trifluoromethanesulfonic acid (TfOH) or bis(trifluoromethane-sulfonyl)imide (Tf2NH), iodosobenzene (PhI=O) efficiently promoted the reactions of dicarbonyl compounds as well as monocarbonyl compounds with nitriles to give 2,4 ...
Yuji Hanzawa, Akio Saito, Nao Hyodo
doaj   +1 more source

Crystal structure, Hirshfeld surface analysis and interaction energy and DFT studies of 3-{(2Z)-2-[(2,4-dichlorophenyl)methylidene]-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-4-yl}propanenitrile

Acta Crystallographica Section E: Crystallographic Communications, 2019
The title compound, C18H12Cl2N2OS, consists of a dihydrobenzothiazine unit linked by a –CH group to a 2,4-dichlorophenyl substituent, and to a propanenitrile unit is folded along the S...N axis and adopts a flattened-boat conformation. The propanenitrile
Nada Kheira Sebbar, Brahim Hni, Tuncer Hökelek, Abdelhakim Jaouhar, Mohamed Labd Taha, Joel T. Mague, El Mokhtar Essassi   +6 more
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Isothiocyanates, Nitriles, and Epithionitriles from Glucosinolates Are Affected by Genotype and Developmental Stage in Brassica oleracea Varieties

Frontiers in Plant Science, 2017
Vegetables of the Brassica oleracea group, such as broccoli, cauliflower, and cabbage, play an important role for glucosinolate consumption in the human diet.
Franziska S. Hanschen, Monika Schreiner
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4-(4-Acetyl-5-methyl-1H-1,2,3-triazol-1-yl)benzonitrile: crystal structure and Hirshfeld surface analysis

Acta Crystallographica Section E: Crystallographic Communications, 2018
The title compound, C12H10N4O, comprises a central 1,2,3-triazole ring (r.m.s. deviation = 0.0030 Å) flanked by N-bound 4-cyanophenyl and C-bound acetyl groups, which make dihedral angles of 54.64 (5) and 6.8 (3)° with the five-membered ring, indicating ...
Julio Zukerman-Schpector, Cássio da S. Dias, Ricardo S. Schwab, Mukesh M. Jotani, Edward R. T. Tiekink   +4 more
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