Results 1 to 10 of about 116,978 (344)

STUDIES IN THE PREPARATION OF NITRILES. III. THE CATALYTIC PREPARATION OF NITRILES. [PDF]

Journal of the American Chemical Society, 1916
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G. D. van Epps, E. Emmet Reid
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Electrolytic Reductron of Nitriles [PDF]

NIPPON KAGAKU KAISHI, 1942
パラヂウムを以て被覆せる白金を陰極として酸性溶液にてCN-基を有する種々の型の化合物の電解還元を研究せんとし,先づ若干の代表的化合物について試みたる結果何れもCN-基は還元せられて相當するアミンを生じたり.
Masaki Ohta
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Synthesis and Combination Studies of Novel Dipeptide Nitriles with Curcumin for a Potent Synergistic Action Against Rhodesain, Cysteine Protease of Trypanosoma brucei rhodesiense [PDF]

Pharmaceuticals
Background/Objectives: Rhodesain is a cysteine protease crucial for the life cycle of Trypanosoma brucei rhodesiense, a parasite that causes the lethal form of human African trypanosomiasis.
Carla Di Chio, Josè Starvaggi, Santo Previti, Fabiola De Luca, Benito Natale, Sandro Cosconati, Tanja Schirmeister, Maria Zappalà, Roberta Ettari   +8 more
doaj   +2 more sources

Antifungal Activity of Glucosinolate-Derived Nitriles and Their Synergistic Activity with Glucosinolate-Derived Isothiocyanates Distinguishes Various Taxa of Brassicaceae Endophytes and Soil Fungi

Plants, 2023
The glucosinolates of Brassicaceae plants are converted into bioactive isothiocyanates and other volatiles during a challenge by pathogens and other biotic stressors.
Zsolt Szűcs, Tamás Plaszkó, Eszter Bódor, Hajnalka Csoma, Lajos Ács-Szabó, Attila Kiss-Szikszai, Gábor Vasas, Sándor Gonda   +7 more
doaj   +1 more source

B–N/B–H Transborylation: borane-catalysed nitrile hydroboration

Beilstein Journal of Organic Chemistry, 2022
The reduction of nitriles to primary amines is a useful transformation in organic synthesis, however, it often relies upon stoichiometric reagents or transition-metal catalysis.
Filip Meger, Alexander C. W. Kwok, Franziska Gilch, Dominic R. Willcox, Alex J. Hendy, Kieran Nicholson, Andrew D. Bage, Thomas Langer, Thomas A. Hunt, Stephen P. Thomas   +9 more
doaj   +1 more source

Room Temperature Reduction of Titanium Tetrachloride-Activated Nitriles to Primary Amines with Ammonia-Borane

Molecules, 2022
The reduction of a variety of aromatic and aliphatic nitriles, activated by a molar equivalent of titanium tetrachloride, has been achieved at room temperature using ammonia borane as a safe reductant. The corresponding methanamines were isolated in good
P. Veeraraghavan Ramachandran, Abdulkhaliq A. Alawaed   +1 more
doaj   +1 more source

A Proterozoic microbial origin of extant cyanide-hydrolyzing enzyme diversity

Frontiers in Microbiology, 2023
In addition to its role as a toxic environmental contaminant, cyanide has been hypothesized to play a key role in prebiotic chemistry and early biogeochemical evolution.
Sarah L. Schwartz, Sarah L. Schwartz, Sarah L. Schwartz, L. Thiberio Rangel, Jack G. Payette, Gregory P. Fournier   +5 more
doaj   +1 more source

Crystal structures of three homologues with increasing ring size: 2-methoxy-4-(thiophen-2-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile, 2-methoxy-4-(thiophen-2-yl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridine-3-carbonitrile and 2-methoxy-4-(thiophen-2-yl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carbonitrile

Acta Crystallographica Section E: Crystallographic Communications, 2023
The title compounds, C15H14N2OS (1a), C16H16N2OS (1b), and C17H18N2OS (1c), form a homologous series in which the size of the saturated ring increases from six- to eight-membered (with four, five and six methylene groups respectively). For 1b and 1c, the
Ali M. S. Hebishy, Galal H. Elgemeie, Lobna M. Gouda, Peter G. Jones   +3 more
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7-Bromo-1-methyl-2-phenyl-1H-indole-3-carbonitrile

Molbank, 2017
The title compound was prepared by electrophilic aromatic substitution of 7-bromo-1-methyl-2-phenyl-1H-indole with NCTS (N-cyano-N-phenyl-p-toluenesulfonamide).
Rosanna Meine, Max Blech, Jens Lindhof, Conrad Kunick   +3 more
doaj   +1 more source

A high-throughput screening method for determining the substrate scope of nitrilases [PDF]

, 2014
Nitrile compounds are intermediates in the synthesis of pharmaceuticals such as atorvastatin. We have developed a chromogenic reagent to screen for nitrilase activity as an alternative to Nessler's reagent. It produces a semi-quantifiable blue colour and
Black, Gary, Brown, Nicola, Perry, Justin, Randall, P. David, Turnbull, Graeme, Zhang, Meng   +5 more
core   +1 more source