Results 121 to 130 of about 14,073 (324)

SYNTHESIS OF THIOHYDROXIMATES THE ADDITION OF THIOLS TO NITRILE OXIDES [PDF]

, 1964
M. H. Benn
openalex   +1 more source

Enantioselective Synthesis of a New Class of Stable and Functionalized Cyclopentadienes via CuH‐Catalysis

Angewandte Chemie, EarlyView.
Cyclopentadienes (CpHs) are fundamental building blocks with widespread applications in chemistry. However, their inherent acidity and isomeric instability have long limited access to chiral variants in an asymmetric fashion. Here, we introduce a CuH‐catalyzed asymmetric transformation that provides an unprecedented entry into a new class of ...
Piero Soppelsa, Riccardo Bellin, Besma Boulila, Francesco Vaghi, Manuel Orlandi   +4 more
wiley   +2 more sources

MnVI-NP–Catalyzed Generation of Nitrile Oxides: Easy Access to Isoxazolines and Isoxazoles via Stereoselective 1,3-Dipolar Cycloaddition Reactions [PDF]

, 2022
Saikat Khamarui, Yasmin Saima
openalex   +1 more source

Iron‐Photocatalyzed C(sp3)–H Phosphonylation of Alkanes

Angewandte Chemie, EarlyView.
Alkyl phosphonates are valuable motifs that can be prepared by phosphonylations of various common functional groups. However, direct phosphonylations of C(sp3)–H bonds are limited to activated positions. Herein, we report an iron‐photocatalyzed phosphonylation of unactivated C(sp3)–H bonds using a novel phosphite radical trap, which is equipped with an
Ya Dong, Wangyujing Han, Hanwen Zhang, Santosh K. Pagire, Harry Meats, Adam Noble, Varinder K. Aggarwal   +6 more
wiley   +2 more sources

Electrosynthesis of Stable Betulin‐Derived Nitrile Oxides and their Application in Synthesis of Cytostatic Lupane‐Type Triterpenoid‐Isoxazole Conjugates [PDF]

, 2021
Jevgeņija Lugiņina, Martin Linden, Māris Bazulis, Viktors Kumpiņš, Anatoly Mishnev, Sergey A. Popov, Tatiana S. Golubeva, Siegfried R. Waldvogel, Elvira E. Shults, Māris Turks   +9 more
openalex   +1 more source

Mitochondria‐Targeting Moieties Based on N‐Tethered Pyridinium Cations

Angewandte Chemie, EarlyView.
Pyridinium cations were benchmarked as mitochondria‐targeting moieties in a panel of N‐tethered fluorescent‐, bioactive‐, and inert‐cargo conjugates. 3,5‐Diphenylpyridinium (DPPy+) is a competent triphenylphosphonium (TPP+) surrogate, combining high mitochondria‐targeting efficiency with lower intrinsic effects on mitochondrial function.
Ivan Džajić, Natalija Trunkelj, Jernej Repas, Maša Kandušer, Lara Smrdel, Stane Pajk, Lovro Žiberna, Irena Mlinarič‐Raščan, Bostjan Markelc, Tim Bozic, Masa Omerzel, Tanja Jesenko, Maja Cemazar, Katja Kološa, Bojana Žegura, Miha Virant, Matic Lozinšek, Hai M. Nguyen, Joshua A. Nasburg, Heike Wulff, Maxime Gueguinou, Valerije Vrček, Veronica Carpanese, Ildiko Szabo, Luis A. Pardo, Tihomir Tomašič, Lucija Peterlin Mašič, Andrej Emanuel Cotman   +27 more
wiley   +2 more sources

Redirecting Excited‐State Proton Transfer Through Supramolecular Polymerization in Nanoconfinement

Angewandte Chemie, EarlyView.
Supramolecular confinement redirects the excited‐state proton transfer pathway of an amphoteric emitter. In water, the molecule undergoes ESPD, whereas co‐assembly with γ‐cyclodextrin forms nanotubes that template slip‐stacked emitter pairs and enable ESIMPT. Structural and photophysical characterization of the assemblies shows that the preorganization
Luis C. Pantaleone, Robert Hutchings, Bente Reus, Jacopo Martinelli, Alessia Lasorsa, Patrick C. A. van der Wel, Marc C. A. Stuart, Wesley R. Browne, Tibor Kudernac   +8 more
wiley   +2 more sources

Formation of 4-Versus 5-Spirocycloadducts -A DFT Investigation of the (3 + 2) Cycloaddition Reaction of Cyclic Nitrone and Nitrile Oxide with Alkylidenecyclopropane

, 2021
Emmanuel Forson, Anthony Amoah, Richard Tia, Evans Adei   +3 more
openalex   +1 more source

A Non‐Covalent [4Fe–4S]/[2Fe] Interface in HydF Guides [FeFe]‐Hydrogenase Maturation

Angewandte Chemie, EarlyView.
Bridged or not? 57Fe NRVS reveals a non‐covalent, electronically coupled interaction between the HydF [4Fe–4S] cluster and the [2Fe] precursor. Boltz‐2 structure predictions suggest that the cubane organizes lipoate‐dependent Hmet chemistry, positioning intermediates for assembly of the CH2–NH–CH2 bridge during H‐cluster biosynthesis.
Giorgio Caserta, Princess R. Cabotaje, Armel T. Waffo, Deepak Prajapat, Ilya Sergueev, Stefan Frielingsdorf, Gustav Berggren   +6 more
wiley   +2 more sources

Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles. [PDF]

Nat Chem Biol, 2020
Eaton JK, Furst L, Ruberto RA, Moosmayer D, Hilpmann A, Ryan MJ, Zimmermann K, Cai LL, Niehues M, Badock V, Kramm A, Chen S, Hillig RC, Clemons PA, Gradl S, Montagnon C, Lazarski KE, Christian S, Bajrami B, Neuhaus R, Eheim AL, Viswanathan VS, Schreiber SL.   +22 more
europepmc   +1 more source