Results 41 to 50 of about 909,766 (269)

Side-chain Modifications of Highly Functionalized 3(2H)-Furanones

Molecules, 2012
A series of 3(2H)-furanones, based on side-chain modifications of a parent 3(2H)-furanone, was synthesized in good yield. The parent compound was prepared by hydrogenolysis, and subsequent acid hydrolysis, of isoxazole derivatives.
Gil Valdo José da Silva, Maurício Gomes Constantino, Viviani Nardini, Shirley Muniz Machado Rodrigues   +3 more
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Synthesis and Antimicrobial Activity of some Ester Functionalized Isoxazoles incorporating Anthracene Moieties via Nucleophilic Substitution Reaction

Zanco Journal of Medical Sciences, 2023
Background and objective: Five-membered heterocycle compounds having single oxygen and nitrogen atom at adjacent positions are known as isoxazoles. Isoxazole compounds have a broad range of biological activities and therapeutic value.
Sarbast M. Ahmed, Hewa Omer Ahmed, Faiq H. S. Hussain, Hayman Sardar Abdulrahman, Hemn A. Qader   +4 more
doaj  

Facile and green synthesis of 3,5-disubstituted isoxazoles using doped nano-sized copper(I) oxide (Cu2O) on melamine–formaldehyde resin as an efficient nano-catalyst under ultrasonic irradiation [PDF]

شیمی کاربردی روز, 2019
In the present research, doped nano-sized copper(I) oxide (Cu2O) on melamine–formaldehyde resin as a heterogeneous and efficient nano-catalyst has been employed for green and mild synthesis of 3,5-disubstituted isoxazoles under ultrasonic irradiation. In
Somayeh Behrouz
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Preparation of in situ modified hydrogenated nitrile rubber with unsaturated carboxylic acid from biomass

Hecheng xiangjiao gongye
Zinc sorbate (ZDS) reinforced hydrogenated nitrile rubber was prepared using sorbic acid and zinc oxide as raw materials by in situ generation method, and the in situ reaction mechanism of sorbic acid and effect of zinc sorbate on physical and mechanical
XUE Ao-nan, LIU Da-chen, ZHU Bo-cong, XIAO Xiao-kun
doaj   +1 more source

The rapid generation of isothiocyanates in flow

Beilstein Journal of Organic Chemistry, 2013
Isothiocyanates are versatile starting materials for a wide range of chemical reactions. However, their high nucleophilic susceptibility means they are best prepared and used immediately.
Marcus Baumann, Ian R. Baxendale
doaj   +1 more source

Adaptive Foam 3D Printing of Ultralight and Multifunctional Materials

Advanced Engineering Materials, EarlyView.
Adaptive foam 3D printing, enabled by expandable microspheres, imparts cellular structures to thermoplastic and thermosetting polymers, manufactured through a variety of processes including fused filament fabrication, direct ink writing, digital light processing, and inkjet printing.
Nariman Rajabifar, Amir Ameli
wiley   +1 more source

Hydroxyl-Directed Nitrile Oxide Cycloaddition Reactions with Cyclic Allylic Alcohols

, 2016
Diastereoselective cycloaddition reactions between a nitrile oxide and cyclic allylic alcohols are reported. The products isolated are densely functionalized building blocks that are not otherwise easily accessed with existing methods and concepts ...
Nina Becker (2476843), Erick M. Carreira (1330920)   +1 more
core   +1 more source

Fabrication Routes for Ionic Conducting Fiber Strain Sensors

Advanced Engineering Materials, EarlyView.
Ionic conducting fiber strain sensors (ICFSs) offer compliant, textile‐integrable sensing. Thus far, the commercialization of ICFSs has been constrained by fiber fabrication routes. This review provides a fabrication‐centric analysis of ICFSs correlating processing strategies with material properties and scalability.
Leo John Kershaw, Zhanhong Yang, Anne Ladegaard Skov, Magdalena Skowyra   +3 more
wiley   +1 more source