Synthetic approaches to biologically active sulfonates and sulfonamides [PDF]
This research describes the scope of 1,3-dipolar cycloaddition between selected 1,3-dipoles (nitrile oxide/nitrone) and dipolarophiles (PFP ethenesulfonate/PFP-1-bromoethenesulfonate). Nitrile oxide cycloaddition with PFP-1-bromoethenesulfonate furnished
Lee, C.C.
core
C-3β-Tethered Functional Cholesterol Conjugates by Nitrile Oxide Alkyne Cycloaddition (NOAC) [PDF]
Covalent cholesterol conjugates have been prepared by isoxazole-generating [3+2] nitrile oxide alkyne cycloaddition (NOAC) chemistry. Steroidal building blocks functionalised with either an alkyne or a nitrile oxide precursor were evaluated. The reaction
O'Sullivan, Justine +2 more
core +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Side-chain Modifications of Highly Functionalized 3(2H)-Furanones
A series of 3(2H)-furanones, based on side-chain modifications of a parent 3(2H)-furanone, was synthesized in good yield. The parent compound was prepared by hydrogenolysis, and subsequent acid hydrolysis, of isoxazole derivatives.
Gil Valdo José da Silva +3 more
doaj +1 more source
Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong +12 more
wiley +1 more source
Background and objective: Five-membered heterocycle compounds having single oxygen and nitrogen atom at adjacent positions are known as isoxazoles. Isoxazole compounds have a broad range of biological activities and therapeutic value.
Sarbast M. Ahmed +4 more
doaj
Facile and green synthesis of 3,5-disubstituted isoxazoles using doped nano-sized copper(I) oxide (Cu2O) on melamineâformaldehyde resin as an efficient nano-catalyst under ultrasonic irradiation [PDF]
In the present research, doped nano-sized copper(I) oxide (Cu2O) on melamine–formaldehyde resin as a heterogeneous and efficient nano-catalyst has been employed for green and mild synthesis of 3,5-disubstituted isoxazoles under ultrasonic irradiation. In
Somayeh Behrouz
doaj +1 more source
REGIOSELECTIVITY AND STEREOSELECTIVITY OF INTRAMOLECULAR NITRILE OXIDE CYCLO-ADDITION TO FURAN
Intramolecular nitrile oxide cycloaddition to functionalized furans occurs with complete regiochemical control but low ...
Mauro Cinquini +7 more
core +1 more source
Underground Signals: The Ecological Power of Root Volatiles
Root volatiles mediate rhizosphere chemical communication, shaping interactions among plants, microbes, herbivores, and natural enemies. Their production, transport, and perception underpin ecological adaptation, multitrophic interactions, and plant resilience, offering opportunities for sustainable crop protection, resilient agroecosystems, and ...
Xueyao Cao +31 more
wiley +1 more source
Zinc sorbate (ZDS) reinforced hydrogenated nitrile rubber was prepared using sorbic acid and zinc oxide as raw materials by in situ generation method, and the in situ reaction mechanism of sorbic acid and effect of zinc sorbate on physical and mechanical
XUE Ao-nan, LIU Da-chen, ZHU Bo-cong, XIAO Xiao-kun
doaj +1 more source

