Results 41 to 50 of about 2,206 (129)

Stereoselective Four-Component Synthesis of Functionalized 2,3-Dihydro-4-Nitropyrroles

Frontiers in Chemistry, 2019
We report a metal-free and stereoselective four-component reaction between α-ketoamides, amines, aromatic aldehydes and β-nitroalkenes or β-pivaloxy-nitroalkanes to obtain 2,3-dihydro-4-nitropyrroles functionalized in every position.
Dong Wang, Xinyue Ma, Linru Dong, Hairong Feng, Peng Yu, Laurent Désaubry, Laurent Désaubry   +6 more
doaj   +1 more source

Acetaldehyde in the Enders triple cascade reaction via acetaldehyde dimethyl acetal

Beilstein Journal of Organic Chemistry, 2023
Asymmetric organocatalyzed multicomponent reactions represent an important toolbox in the field of organic synthesis to build complex scaffolds starting from simple starting materials.
Alessandro Brusa, Debora Iapadre, Maria Edith Casacchia, Alessio Carioscia, Giuliana Giorgianni, Giandomenico Magagnano, Fabio Pesciaioli, Armando Carlone   +7 more
doaj   +1 more source

Oxidative Aromatization of 4,7-Dihydro-6-nitroazolo[1,5-a]pyrimidines: Synthetic Possibilities and Limitations, Mechanism of Destruction, and the Theoretical and Experimental Substantiation

Molecules, 2021
The reaction tolerance of the multicomponent process between 3-aminoazoles, 1-morpholino-2-nitroalkenes, and aldehydes was studied. The main patterns of this reaction have been established.
Daniil N. Lyapustin, Evgeny N. Ulomsky, Ilya A. Balyakin, Alexander V. Shchepochkin, Vladimir L. Rusinov, Oleg N. Chupakhin   +5 more
doaj   +1 more source

Ring Formation in Sesquiterpene Synthesis: Biomimetic vs. Non‐Biomimetic Strategies

European Journal of Organic Chemistry, Volume 29, Issue 5, 7 February 2026.
A short review of cyclase enzyme‐mediated ring formation in sesquiterpene biosynthesis is presented as a prelude to six case studies examining the merits and demerits of biomimetic vs. non‐biomimetic strategies for carbocyclisation in the total synthesis of this iconic natural product class.
Bohan Lin, Chen Dai, Alan C. Spivey
wiley   +1 more source

Nitrogen‐Rich, Tröger's Base‐Linked Porous Organic Polymers (POPs) as Heterogeneous Catalysts and Adsorbents of Organic Pollutants From Water

Journal of Applied Polymer Science, Volume 143, Issue 3, January 15, 2026.
Synthesized Tröger's based POPs showed great versatility in heterogeneous catalysis reactions and for pollutant adsorption. ABSTRACT Porous organic polymers are a new class of polymeric materials that combine permanent porosity, high surface area, monomer diversity, and synthetic tunability, making them highly promising candidates for application in ...
Tiago F. Machado, Saúl Vallejos, Artur J. M. Valente, M. Elisa Silva Serra, Dina Murtinho   +4 more
wiley   +1 more source

Catalyst-free and solvent-free Michael addition of 1,3-dicarbonyl compounds to nitroalkenes by a grinding method

Beilstein Journal of Organic Chemistry, 2012
An environmentally benign, fast and convenient protocol has been developed for the Michael addition of 1,3-dicarbonyl compounds to β-nitroalkenes in good to excellent yields by a grinding method under catalyst- and solvent-free conditions.
Zong-Bo Xie, Na Wang, Ming-Yu Wu, Ting He, Zhang-Gao Le, Xiao-Qi Yu   +5 more
doaj   +1 more source

Catalytic Asymmetric 1,4-Additions of β-Keto Esters to Nitroalkenes Promoted by a Bifunctional Homobimetallic Co2-Schiff Base Complex

Molecules, 2010
Catalytic asymmetric 1,4-addition of β-keto esters to nitroalkenes is described. 2.5 mol % of a homobimetallic Lewis acid/Brønsted base bifunctional Co2-Schiff base complex smoothly promoted the reaction in excellent yield (up to 99 ...
Masakatsu Shibasaki, Shigeki Matsunaga, Zhihua Chen, Makoto Furutachi   +3 more
doaj   +1 more source

Nitration of GlcCer and Related Complex Lipids Enhances CD1d Binding Affinity and Modulates Immune Responses via Lipid Antigen Presentation to Natural Killer T Cells

ChemistryEurope, Volume 4, Issue 1, January 2026.
Nitration of glycolipids and phospholipids increases their binding to CD1d. Nitrated β‐GlcCer and phospholipids show strong CD1d binding but induce minimal cytokine production, suggesting potential immune suppression. In contrast, nitrated endogenous‐type α‐GalCer enhances cytokine responses, indicating that nitrated lipids can modulate CD1d‐mediated ...
Kodai Sueyoshi, Nanako Kawate‐Horiuchi, Kazunari Ueki, Risa Nozawa, Takanori Matsumaru, Yukari Fujimoto   +5 more
wiley   +1 more source

Exploring Isophorone‐Based Dienones: Comprehensive Insights Into Their Synthesis, Reactivity, and Diverse Applications

Journal of Chemistry, Volume 2026, Issue 1, 2026.
Isophorone is an important motif in synthetic organic chemistry, as it is highly reactive and can get involved in a diverse array of functional group transformations to access various synthetic intermediates and molecular targets. In this context, an important group of compounds is the conjugated or nonconjugated isophorone‐cored dienones, which are ...
M. Saeed Abaee, Mohammad M. Mojtahedi, Sohini Basu Roy   +2 more
wiley   +1 more source

Fatty acid nitroalkenes regulate intestinal lipid absorption

Journal of Lipid Research
Fatty acid nitroalkenes (NO2-FA) are tissue-protective and anti-inflammatory endogenous lipid mediators. A unique electrophilic character promotes reversible reactions with protein thiols, influencing key cellular functions. Given their generation during
Francisco J. Schopfer, Lihong Teng, Ahssan Sekandari, Ese S. Ekhator, Alison B. Kohan, Bruce A. Freeman, Marco Fazzari   +6 more
doaj   +1 more source