Results 41 to 50 of about 3,335 (198)

Direct Conversion of 3-(2-Nitroethyl)-1H-Indoles into 2-(1H-Indol-2-yl)Acetonitriles

Molecules, 2021
The recently discovered [4+1]-spirocyclization of nitroalkenes to indoles provided a convenient new approach to 2-(1H-indol-2-yl)acetonitriles. However, this reaction was complicated by the formation of inert 3-(2-nitroethyl)-1H-indole byproducts. Herein,
Alexander V. Aksenov, Nicolai A. Aksenov, Elena V. Aleksandrova, Dmitrii A. Aksenov, Igor Yu. Grishin, Elena A. Sorokina, Allison Wenger, Michael Rubin   +7 more
doaj   +1 more source

Enantioselective 1,3-Dipolar Cycloaddition Using (Z)-α-Amidonitroalkenes as a Key Step to the Access to Chiral cis-3,4-Diaminopyrrolidines

Molecules, 2022
The enantioselective 1,3-dipolar cycloaddition between imino esters and (Z)-nitroalkenes bearing a masked amino group in the β-position was studied using several chiral ligands and silver salts.
Eduardo García-Mingüens, Marcos Ferrándiz-Saperas, M. de Gracia Retamosa, Carmen Nájera, Miguel Yus, José M. Sansano   +5 more
doaj   +1 more source

Hydrogen bond-mediated organocatalytic enantioselective reduction of nitroalkenes in deep eutectic solvents

Tetrahedron Chem, 2023
The catalytic enantioselective reduction of β,β-disubstituted nitroalkenes was performed in deep eutectic solvents, avoiding the use of volatile organic compounds (VOCs) as reaction medium.
Chiara Faverio, Monica Fiorenza Boselli, Tommaso Ruggiero, Laura Raimondi, Maurizio Benaglia   +4 more
doaj   +1 more source

Amino Imidate Catalyzed Asymmetric Michael Reactions of Ketones and Nitroalkenes

SynOpen, 2022
The efficiency of an amino imidate organocatalyst was evaluated in the Michael reaction of ketones with nitroalkenes. tert-Butyl­ l-proline imidate was found to be a syn-selective catalyst, generating products with moderate to good enantioselectivities ...
Bohdan Sosunovych, Alexander J. Brown, Paul A. Clarke   +2 more
doaj   +1 more source

Control of Helix Screw‐Sense Preference in Dynamic Foldamers of meso Symmetry Built From Chiral Monomeric Units

Angewandte Chemie International Edition, EarlyView.
Sequence‐diverse meso and “near‐meso” oligourea foldamers are reported and exhibit stimulus‐responsive helix screw‐sense control governed by terminal‐group desymmetrization and sequence‐encoded helix stability. ABSTRACT Meso oligoureas are dynamic hydrogen‐bonded foldamers capable of reversible helix polarity inversion but have so far been limited to ...
Naveen Gupta, Mégane Bornerie, Bo Li, Antoine Hacihasanoglu, Orlando Villegas Bello, Stéphanie Antunes, Estelle Morvan, Jean‐Marc Sotiropoulos, Philippe Carbonnière, Morgane Pasco, Brice Kauffmann, Céline Douat, Sung Hyun Yoo, Gilles Guichard   +13 more
wiley   +1 more source

Enantioselective Michael addition of 2-hydroxy-1,4-naphthoquinones to nitroalkenes catalyzed by binaphthyl-derived organocatalysts

Beilstein Journal of Organic Chemistry, 2012
The highly enantioselective Michael addition of 2-hydroxy-1,4-naphthoquinones to nitroalkenes, promoted by binaphthyl-modified chiral bifunctional organocatalysts is described.
Saet Byeol Woo, Dae Young Kim
doaj   +1 more source

Bromonitroalkanes in Organic Synthesis

European Journal of Organic Chemistry, EarlyView.
α,α‐Bromonitroalkanes (BNAs) exhibit chameleon‐like reactivity, serving as carbene, radical, carbanion, and carbocation synthons. This mini‐review summarizes the different reaction modes and highlights recent developments in thermal and photochemical processes. α,α‐Bromonitroalkanes (BNAs) exhibit chameleon‐like reactivity, serving as carbene, radical,
Magdalena Koch, Oliver Reiser
wiley   +1 more source

Metal‐Catalyzed Benzannulation: Recent Advances in Catalyst Design, Mechanistic Insights, and Aromatic Framework Construction

The Chemical Record, EarlyView.
This review offers a contemporary overview of metal‐catalyzed benzannulation (2018–present) encompassing transition, main‐group, post‐transition, and rare‐earth‐metal catalysts. It systematically highlights catalyst design, mechanistic insights, stereo‐ and regioselectivity, and synthetic applications toward aromatic and heteroaromatic scaffolds, while
Sana Jamshaid, Divya Shrestha, Raju S. Thombal, Jeung Gon Kim, Kim Seong Cheol, Yong Rok Lee   +5 more
wiley   +1 more source

Synthesis and anticancer activity studies of α-aminoalkylated conjugated nitroalkenes

, 2006
The synthesis of α-aminoalkylated conjugated nitroalkenes with imidazole/LiCi-mediated reaction of conjugated nitroalkenes with N-tosylimines were investigated.
Rastogi, Namrata, Panda, Dulal, Namboothiri, Irishi N. N., Mohan, Renu, Mobin, Shaikh M.   +4 more
core   +2 more sources

Navigating Nitration Chemistry: A Practical Guide to Reagents, Mechanisms, and Selectivity

Angewandte Chemie, Volume 138, Issue 20, 11 May 2026.
This review highlights key contributions of modern nitration chemistry, emphasizing sustainable mechanistic platforms and comparing the performance of both organic and inorganic reagents across aromatic, ipso‐, olefin, alkyne, and heteroatom nitration. It provides the community with a clearer, unified perspective on current advances and facilitates the
Harry Lecomte, Anthony J. Fernandes, Dmitry Katayev   +2 more
wiley   +2 more sources