NRF2 Activation by Nitrogen Heterocycles: A Review [PDF]
Molecules, 2023 Several nitrogen heterocyclic analogues have been applied to clinical practice, and about 75% of drugs approved by the FDA contain at least a heterocyclic moiety.
Melford C. Egbujor +4 more
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Structure and Stability of Aromatic Nitrogen Heterocycles Used in the Field of Energetic Materials [PDF]
Molecules, 2020 Understanding the stabilization of nitrogen heterocycles is critical in the field of energetic materials and calls for innovative knowledge of nitrogen aromatics.
He-Hou Zong +4 more
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Nitrogen heterocycles form peptide nucleic acid precursors in complex prebiotic mixtures [PDF]
Scientific Reports, 2019 The ability to store information is believed to have been crucial for the origin and evolution of life; however, little is known about the genetic polymers relevant to abiogenesis.
Laura E. Rodriguez +4 more
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Synthesis of Nitrogen Heterocycles Using Samarium(II) Iodide [PDF]
Molecules, 2017 Nitrogen heterocycles represent vital structural motifs in biologically-active natural products and pharmaceuticals. As a result, the development of new, convenient and more efficient processes to N-heterocycles is of great interest to synthetic chemists.
Shicheng Shi, Michal Szostak
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Nitrogen Containing Heterocycles as Anticancer Agents: A Medicinal Chemistry Perspective
Pharmaceuticals, 2023 Cancer is one of the major healthcare challenges across the globe. Several anticancer drugs are available on the market but they either lack specificity or have poor safety, severe side effects, and suffer from resistance.
Adarsh Kumar +14 more
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Copper catalyzed late-stage C(sp3)-H functionalization of nitrogen heterocycles. [PDF]
Nat Commun, 2021 Nitrogen heterocycle represents a ubiquitous skeleton in natural products and drugs. Late-stage C(sp3)-H bond functionalization of N-heterocycles with broad substrate scope remains a challenge and of particular significance to modern chemical synthesis ...
Chang Z +6 more
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Sulfur-Nitrogen Heterocycles [PDF]
Molecules, 2005 n ...
Tomás Torroba +1 more
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Rhodium-Catalyzed C-H Alkenylation/Electrocyclization Cascade Provides Dihydropyridines That Serve as Versatile Intermediates to Diverse Nitrogen Heterocycles. [PDF]
Acc Chem Res, 2021 ConspectusNitrogen heterocycles are present in approximately 60% of drugs, with nonplanar heterocycles incorporating stereogenic centers being of considerable interest to the fields of medicinal chemistry, chemical biology, and synthetic methods ...
Dongbang S, Confair DN, Ellman JA.
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Prescribed drugs containing nitrogen heterocycles: an overview. [PDF]
RSC Adv, 2020 Heteroatoms as well as heterocyclic scaffolds are frequently present as the common cores in a plethora of active pharmaceuticals natural products.
Heravi MM, Zadsirjan V.
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Microwave assisted synthesis of five membered nitrogen heterocycles. [PDF]
RSC Adv, 2020 Our continuously changing environment demands sensible and sustainable chemistry. Consequently, organic synthesis started to follow green chemistry principles in recent years.
Meera G +3 more
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