How Not to Discover a New Reagent. The Evolution and Chemistry of Woollins' Reagent [PDF]
, 2012 The pathways in research can be complex. This review provides a personal account of the winding scientific and funding road that led to Woollins' reagent.
Woollins, J. Derek
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Diquaternary Ammonium Compounds in Zeolite Synthesis: Cyclic and Polycyclic N-Heterocycles Connected by Methylene Chains [PDF]
, 2009 An additional dimension has been added to our long-standing studies in high silica zeolite synthesis via a guest/host synergism. We have created and studied the impact of making symmetric diquaternary ammonium compounds, by varying the chain length ...
Burton, Allen W. +3 more
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Transfer of electrophilic NH using convenient sources of ammonia: direct synthesis of N–H sulfoximines from sulfoxides [PDF]
, 2016 The transfer of nitrogen atoms is extremely valuable in the preparation of medicinal compounds. Here, a new system for NH transfer is developed to prepare sulfoximines, which are emerging as valuable motifs for drug discovery.
Bentley +43 more
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Insertion of ammonia into alkenes to build aromatic N-heterocycles
Nature Communications, 2022 Aromatic heterocycles containing nitrogen are ubiquitous in biologically relevant small molecules. Here the authors show an unorthodox methodology for their synthesis, by inserting the nitrogen atom into a carbon ring, with ammonia in electrochemical ...
Shuai Liu, Xu Cheng
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Hydrazones as Singular Reagents in Asymmetric Organocatalysis [PDF]
, 2016 This Minireview summarizes strategies and developments regarding the use of hydrazones as reagents in asymmetric organocatalysis, their distinct roles in nucleophile–electrophile, cycloaddition, and cyclization reactions.
Fernández Fernández, Rosario Fátima +4 more
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The Nitrogen Heterocycle Content of Meteorites and Their Significance for the Origin of Life
Life, 2018 Carbonaceous chondrites are very primitive meteorites that are rich in carbon. They contain many soluble organic compounds, including nitrogen heterocycles.
Zita Martins
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Synthesis of arylamines and N-heterocycles by direct catalytic nitrogenation using N2
Nature Communications, 2021 Ammonia and nitric acid are key platform chemicals to introduce nitrogen into organic molecules, however gaseous N2 would be a more direct and available source of nitrogen.
Kai Wang +5 more
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Asymmetric addition of chiral boron-ate complexes to cyclic iminium ions [PDF]
, 2014 Boron-ate complexes derived from enantioenriched secondary benzylic boronic esters and aryl lithiums have been reacted with quinolinium, pyridinium and dihydroisoquinolinium salts to give enantioenriched heterocyclic structures with very high ...
Aggarwal, Varinder K. +4 more
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Synthesis of Enantiopure Oxygen- and Nitrogen-Containing Heterocycles by Diastereoselective Ring-Closing Metathesis Reaction in Perhydro-1,3-benzoxazine Derivatives [PDF]
, 2019 Producción CientíficaDiastereoselective ring‐closing metathesis reactions on chiral trienic perhydro‐1,3‐benzoxazines derived from (−)‐8‐aminomenthol featuring two diastereotopic olefin chains is described.
Andrés Juan, Celia +4 more
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Various Synthesis of Imidazo[1,2-a]pyridines Derivatives and Therapeutic Significance: A Review [PDF]
BIO Web of ConferencesThe synthesis of bicyclic heterocycles, notably nitrogen-containing imidazopyridines, holds immense appeal due to their structural diversity and pivotal role in biological systems. These compounds are ubiquitously found in nature and are prized for their
Hamdi Abdeljalil +7 more
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