Results 141 to 150 of about 4,252 (181)

Nitroimidazole-induced chronic hepatitis

European Journal of Gastroenterology & Hepatology, 2001
Drug-induced chronic hepatitis is a rare pathological condition. There is no reported case with chronic hepatitis secondary to nitroimidazole use. We report a patient who developed nitroimidazole-induced chronic hepatitis following acute exacerbation of hepatitis three times after nitroimidazole use.
Ersoz, G, Karasu, Z, Akarca, US, Gunsar, F, Yuce, G, Batur, Y   +5 more
openaire   +3 more sources

Pharmacokinetics of Nitroimidazoles

1982
In this paper I want to try and show how a knowledge of the metabolism and pharmacokinetics of a compound helps us to understand the reasons why it may or may not satisfy the criteria desired of a particular drug. How we want a drug to behave depends on the use we have in mind for it. For example, in Fig.
T. R. Marten, R. J. Ruane, J. A. White, L. Clarke   +3 more
openaire   +1 more source

Nitroimidazoles as Anti-Tumor Agents

Anti-Cancer Agents in Medicinal Chemistry, 2011
At present cancer treatment is still a confusing problem. Great progress has been made in anti-tumor agents since a series of small molecules are approved by FDA as anti-tumor drugs. Nitroimidazoles is a kind of radiosensitizer with multiple bioactivities used in cancer treatment since 1950s.
Kai, Liu, Hai-Liang, Zhu
openaire   +2 more sources

Antiparasitic Nitroimidazoles: 6. The Metabolism and Excretion of Some 2-Styryl-5-nitroimidazoles

Xenobiotica, 1973
Abstract1. The metabolism and excretion of several 2-styryl-5-nitroimidazoles, which have shown interesting antiparasitic activity in laboratory animals, is described.2. Species differences have been observed in the formation of metabolites by oxidation of the alkyl group of the styryl nucleus.3.
D M, Morton, D M, Fuller, J N, Green
openaire   +2 more sources

Cost of nitroimidazoles

Medical Journal of Australia, 1984
David Cranna, Allan J. McLean, Lisa L. Ioannides‐Demos, W. John Spicer   +3 more
openaire   +2 more sources

Safety of nitroimidazoles.

Scandinavian journal of infectious diseases. Supplementum, 1986
The nitroimidazoles used in the treatment of anaerobic infection are well-tolerated by patients. With the possible exception of neurotoxic effects associated with high dosage, signs and symptoms of toxicity are transient and disappear soon after withdrawal of treatment.
openaire   +1 more source

Antiparasitic nitroimidazoles. 1. 2-Styryl-5-nitroimidazoles

Journal of Medicinal Chemistry, 1972
W J, Ross, W B, Jamieson, M C, McCowen
openaire   +2 more sources

Evaluation of the selectivity of molecularly imprinted polymer cartridges for nitroimidazoles. Application to the simultaneous extraction of nitroimidazoles and benzimidazoles from samples of animal origin

Microchemical Journal, 2022
Myriam Bustamante-Rangel, Encarnacion Rodríguez-Gonzalo   +1 more
exaly  

Synthesis, thermal hazard analysis and density functional theory study of nitroimidazoles

Thermochimica Acta, 2022
Xiaosong Xu, Renfa Zhang, Congming Ma
exaly  

Bacteroides fragilis and nitroimidazoles

Journal of Antimicrobial Chemotherapy, 1976
I R, Ferguson, L L, Smith
openaire   +2 more sources