Results 21 to 30 of about 8,002 (167)

Environmental Factors in the Relapse and Recurrence of Inflammatory Bowel Disease:A Review of the Literature [PDF]

, 2015
The causes of relapse in patients with Crohn's disease (CD) and ulcerative colitis (UC) are largely unknown. This paper reviews the epidemiological and clinical data on how medications (non-steroidal anti-inflammatory drugs, estrogens and antibiotics ...
A Bitton, A Bitton, A Dignass, A Kaser, A Lunderquist, A Timmer, AJ Wakefield, AM Meyer, AN Ananthakrishnan, Andrew R. Hart, AP Dhillon, B Boye, BD Levy, C Abraham, C Luong, C Mowat, CN Bernstein, CS Guerreiro, CS North, D Lader, DA Gorard, DC Baumgart, DC Baumgart, E Lindberg, E Stepien, EA Magee, EA Magee, EA Miles, EF Foley, EM Sternberg, F Backhed, F Casellas, FN Aberra, G Bonizzi, G Bouma, G Cipolla, G Savoye, GE Reese, GF Bonner, GP Chrousos, H Brunner, H Tornqvist, IC Solberg, J Cosnes, J Cosnes, J Cosnes, J Eaden, JA Dominitz, JA Mancini, JB Felder, JC Meijers, JM Evans, KJ Khan, KS Rothfuss, L Beaugerie, L Beaugerie, L LeResche, L Lu, LM Lichtenberger, LR Sutherland, LR Sutherland, M Aslam, M Cottone, M Dybdahl, MB Grisham, MC Aldhous, MC Pitcher, MN Merrett, MT Severinsen, NJ Simmonds, NP Thompson, O Hovde, OA Hatoum, P Seksik, PJ Loll, R Reid, R Schreck, RD Cohen, RK Linskens, RM Beattie, RS Barua, S Danese, S Hayashi, S Levenstein, S Parcell, S Sigaud, S Singh, S Zhang, Simon S. M. Chan, SL Jowett, SM Collins, SM Collins, SS Hecht, ST Smale, SU Christl, SV Kane, T Hisamatsu, THJ Florin, Thomas D. Martin, U Erikson   +99 more
core   +1 more source

Activatable smart contrast agents for photoacoustic imaging

Smart Molecules, EarlyView.
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh, Jihye Lee, Suyoung Park, Juyoung Yoon, Won Jong Kim, Chulhong Kim   +5 more
wiley   +1 more source

A structured, behavioural science approach to the preparation of antimicrobial stewardship interventions for companion animal veterinarians

Veterinary Record, EarlyView.
Abstract Background A structured, behavioural science approach was adopted to develop antimicrobial stewardship interventions in UK first‐opinion companion animal veterinary practice. The objectives were to identify behavioural targets for intervention and to understand how practice contexts influence these behaviours.
Ben Walker, Dan O'Neill, Huw Stacey, Dave Brodbelt   +3 more
wiley   +1 more source

Research advances in the applications of mitochondria‐targeted cyanine dyes in imaging

VIEW, EarlyView.
Near‐infrared (NIR) fluorescence imaging, a novel non‐invasive diagnostic tool, plays a crucial role in the imaging and monitoring of solid tumors. At its core are NIR fluorescent dyes, which are widely utilized due to their ability to minimize tissue autofluorescence interference, thereby significantly enhancing the signal‐to‐noise ratio (SNR) and ...
Hongye Liao, Jingyu Deng, Qin Li, Tong Xia, Xun Yang, Simei Yang, Changzhen Sun, Xia Xiong, Li Liu   +8 more
wiley   +1 more source

Repositioning Antitubercular 6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazoles for Neglected Tropical Diseases: Structure-Activity Studies on a Preclinical Candidate for Visceral Leishmaniasis. [PDF]

, 2016
6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazole derivatives were initially studied for tuberculosis within a backup program for the clinical trial agent pretomanid (PA-824).
Blaser, Adrian, Denny, William A, Franzblau, Scott G, Gupta, Suman, Launay, Delphine, Ma, Zhenkun, Maes, Louis, Martin, Denis, O'Connor, Patrick D, Thompson, Andrew M, Wan, Baojie, Wang, Yuehong, Yardley, Vanessa   +12 more
core   +3 more sources

Autogenous Demineralized Dentin Graft–Based Strategies With or Without I‐PRF and Metronidazole for Ridge Preservation in Infected Sockets: A Randomized Clinical Trial

Journal of Periodontal Research, EarlyView.
This randomized controlled trial evaluated the efficacy of demineralized dentin graft (DDG) combined with injectable platelet‐rich fibrin (I‐PRF) and metronidazole (MTZ) versus DDG with or without I‐PRF in alveolar ridge preservation (ARP) of infected extraction sockets.
Mohamed Talaat Elbehwashy, Manal Mohamed Hosny, Ahmed Elfana, Heba Ahmed Saleh, Karim Fawzy El‐Sayed   +4 more
wiley   +1 more source

Long-Term Antibiotic Treatment for Crohn's Disease: Systematic Review and Meta-Analysis of Placebo-Controlled Trials [PDF]

, 2017
Background. We investigated the effectiveness of long-term antibiotic treatment in patients with Crohn's disease. Methods. We performed a systematic review and meta-analysis of randomized clinical trials. Data sources were Medline (from 1966 through June
Egger, Matthias, Feller, Martin, Furrer, Hansjakob, Huwiler, Karin, Schoepfer, Alain, Shang, Aijing   +5 more
core  

Comparison of the voltammetric behavior of metronidazole at a DNA-modified glassy carbon electrode, a mercury thin film electrode and a glassy carbon electrode [PDF]

, 1997
The electroanalytical performance at three electrodes: DNA-modified galssy carbon electrode, mercury thin film electrode and glassy carbon electrode, for the study of the electrochemical reduction of metronidazole is compared. All three electrodes showed
Brett, Ana Maria Oliveira, Gutz, Ivano G. R., La-Scalea, Mauro A., Serrano, Sílvia H. P.   +3 more
core   +1 more source

Nitroimidazoles for imaging hypoxic myocardium

Journal of Nuclear Cardiology, 1995
A series of radiopharmaceuticals that incorporate nitroimidazole moieties have been synthesized to detect decreased local tissue pO2. In contrast to agents that localize in proportion to perfusion, these agents concentrate in hypoxic tissue. Myocardium with an intracellular pO2 < 3 mm Hg (about 25% of normal), which has lost its contractile ability but
H W, Strauss, A, Nunn, K, Linder
openaire   +2 more sources

Genotoxicity profile of fexinidazole—a drug candidate in clinical development for human African trypanomiasis (sleeping sickness) [PDF]

, 2017
The parasitic disease human African trypanomiasis (HAT), also known as sleeping sickness, is a highly neglected fatal condition endemic in sub-Saharan Africa, which is poorly treated with medicines that are toxic, no longer effective or very difficult to
Bourdin Trunz, Bernadette, Torreele, Els, Tweats, David   +2 more
core