Results 171 to 180 of about 13,292 (250)

Bioorthogonal Reactions Utilizing Nitrones as Versatile Dipoles in Cycloaddition Reactions.

Chemical Reviews, 2021
Bioorthogonal chemical reactions have emerged as convenient and rapid methods for incorporating unnatural functionality into living systems. Different prototype reactions have been optimized for use in biological settings.
D. A. Bilodeau   +3 more
semanticscholar   +1 more source

Enantioselective Oxidative Multi-Functionalization of Terminal Alkynes with Nitrones and Alcohols for Expeditious Assembly of Chiral α-Alkoxy-β-amino-ketones.

Journal of the American Chemical Society, 2021
Catalytic oxidative functionalization of alkynes has emerged as an effective method in synthetic chemistry in recent decades. However, enantioselective transformations via metal carbene intermediates are quite rare due to the lack of robust chiral ...
Su Zhou   +5 more
semanticscholar   +1 more source

Photoredox-Catalyzed Decarboxylative Cross-Coupling of α-Amino Acids with Nitrones.

Organic Letters, 2021
A decarboxylative cross-coupling reaction of α-amino acids with nitrones via visible-light-induced photoredox catalysis has been established for easy access to β-amino hydroxylamines and vicinal diamines with structural diversity, which is featured with ...
Hengyuan Li   +3 more
semanticscholar   +1 more source

Regio- and Enantioselective (3+3) Cycloaddition of Nitrones with 2-Indolylmethanols Enabled by Cooperative Organocatalysis.

Angewandte Chemie, 2020
The regio- and enantioselective (3+3) cycloaddition of nitrones with 2-indolylmethanols was accomplished by the cooperative catalysis of hexafluoroisopropanol (HFIP) and chiral phosphoric acid (CPA).
Tian‐Zhen Li   +7 more
semanticscholar   +1 more source

Recent Advances on Nitrones Design for Stroke Treatment.

Journal of Medicinal Chemistry, 2020
The recent advances of tetramethylpyrazine nitrones and quinolylnitrones for the treatment of stroke have been reviewed and compared with other agents, showing promising therapeutic applications.
J. Marco-Contelles
semanticscholar   +1 more source

Acid-catalyzed 1,3-dipolar cycloaddition of 2H-azirines with nitrones: an unexpected access to 1,2,4,5-tetrasubstituted imidazoles.

Journal of Organic Chemistry, 2020
The first 1,3-dipolar cycloaddition of 2H-azirines with nitrones, a straightforward approach towards the regioselective synthesis of 1,2,4,5-tetrasubstituted imidazoles, is reported.
A. Angyal   +4 more
semanticscholar   +1 more source

Synthesis and Transformations of Nitrones for Organic Synthesis.

Chemical Reviews, 2019
Nitrones are important compounds and are highly useful in many aspects. The first part describes the methods for synthesis of nitrones, which are useful and environmentally friendly.
S. Murahashi, Y. Imada
semanticscholar   +1 more source

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