Results 51 to 60 of about 12,404 (251)
Antioxidants, 2020 Nitrones have a well-recognized capacity as spin-traps and are considered powerful free radical scavengers, which are two important issues in hypoxia-induced oxidative stress and cell death in brain ischemia.
Emma Martínez-Alonso +9 more
doaj +1 more source
Metabolic stability of superoxide adducts derived from newly developed cyclic nitrone spin traps [PDF]
, 2014 Reactive oxygen species are by-products of aerobic metabolism involved in the onset and evolution of various pathological conditions. Among them, the superoxide radical is of special interest as the origin of several damaging species such as H2O2 ...
Bézière, Nicolas +5 more
core +1 more source
ChemistryEurope, EarlyView.The cis‐2,3‐bis(trifluoromethyl)cyclopropyl chemotype is introduced. The steric demand of this motif is intermediate between that of the heptafluoroisopropyl and prefluorotertbutyl groups; yet, it induces significantly less lipophilicity than these due to its facial polarity.
Daniel Gaviña +5 more
wiley +1 more source
2-Butyl-2-tert-butyl-5,5-diethylpyrrolidine-1-oxyls: Synthesis and Properties
Molecules, 2020 Nitroxides are broadly used as molecular probes and labels in biophysics, structural biology, and biomedical research. Resistance of a nitroxide group bearing an unpaired electron to chemical reduction with low-molecular-weight antioxidants and enzymatic
Irina F. Zhurko +8 more
doaj +1 more source
Molecules, 2021 The molecular mechanism of the [3 + 2] cycloaddition reaction between C-arylnitrones and perfluoro 2-methylpent-2-ene was explored on the basis of DFT calculations. It was found that despite the polar nature of the intermolecular interactions, as well as
Katarzyna Mitka +3 more
doaj +1 more source
Photochemistry of Aromatic N‐Oxides in Water Probed by Time‐Resolved X‐ray Absorption Spectroscopy
Chemistry – A European Journal, EarlyView.Time‐resolved XAS at the nitrogen and oxygen K‐edges is applied to the photorearrangement of two N‐oxides in water. Pyridine N‐oxide rapidly forms the oxaziridine isomer. Pyridazine N‐oxide undergoes ring opening to the diazo compound, without any evidence of intermediates.
Maximilian Paradiz Domínguez +3 more
wiley +1 more source
RuO4-mediated oxidation of secondary amines: Part 1. Are hydroxylamines main intermediates? [PDF]
Journal of the Serbian Chemical Society, 2016 The RuO4-catalyzed oxidation of secondary amines Bn-NH-CH2R (1a-b; R=H, Me) gave mainly amides, but minute amounts of nitrones PhCH=N(O)-CH2R (9a-b) and traces of Bn-N(OH)-CH2R (R=H, 4a) were also detected.
Florea Cristina A., Petride Horia
doaj +1 more source
Effect of pH on superoxide/ hydroperoxyl radical trapping by nitrones: an EPR/kinetic study
, 2008 International audienceThe pH dependence of the apparent rate constant kTap for O2-./HO2. trapping by four nitrones was examined. In each case, kinetic curves were obtained after treatment of EPR spectra of the spin adduct formed using both singular value
Lauricella, Robert Paul +1 more
core +3 more sources
ESR study of the spin adducts of three analogues of DEPMPO substituted at C-4 or C-3 [PDF]
, 2014 In the research program of some new derivatives of spin-trap DEPMPO (5-diethoxyphosphoryl-5-methyl-1-pyrroline-N-oxide) leading to various radical adducts with photogenic ESR signals, three phosphorylated pyrroline-N-oxides were studied in spin trapping.
Chalier, Florence +4 more
core +3 more sources
Controlling Competitive Radical Pathways: Insights from Aryl Diazonium Electrografting
Chemistry – A European Journal, EarlyView.This work shows that nitrobenzene diazonium electrografting results from competition between aryl and diazenyl radicals, which govern film composition. Using simulations and control strategies, grafting conditions are tuned to favor specific radicals. It enables selective formation of azo‐enriched films and paves the way toward the precise control of ...
Sara Helis +5 more
wiley +1 more source