Results 201 to 210 of about 653,368 (363)

Pumping up immunity: exercise flexes memory NK cell attack. [PDF]

Blood Adv
Phillips EK, Fehniger TA.
europepmc   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Epstein-Barr Virus-Associated T/NK-Cell Neoplasms. [PDF]

J Med Virol
Sato Y, Okuno Y, Murata T, Kimura H.
europepmc   +1 more source

Reduced Maintenance DNA Methylation Thresholds Enable Sensitive Reporter Assays for UHRF1 and DNMT1 Inhibition

Advanced Science, EarlyView.
The authors engineer colorectal cancer cells with reduced redundancy of UHRF1 and DNMT1, key DNA methylation maintenance factors, lowering the maintenance threshold and sensitizing cells to inhibition. They develop reporter assays driven by endogenous tumor‐suppressor gene promoters with enhanced sensitivity and dynamic range to demethylating drugs ...
Cuicui Xia, Ying Cui, Jiongliang Wang, Wenjing Bai, Danyang Wang, Yao Chen, Huahui Guo, Liangyi Zong, Bing Qin, Xintong Cai, Jie Wang, Jing Huang, Scott B. Rothbart, Zufeng Guo, Stephen B. Baylin, Xiangqian Kong   +15 more
wiley   +1 more source

Regulatory T cells and regulatory NK cells play essential roles for maintenance of pregnancy

, 2012
Shigeru Saito, Tomoko Shima, Akitoshi Nakashima   +2 more
openalex   +2 more sources

Mechanism of NK-cell mediated cytotoxicity [PDF]

, 1986
Pierre A. Henkart
openalex   +1 more source

Building a better natural killer (NK) cell: Fc receptor engineering strategies for NK cell therapeutics. [PDF]

Future Virol
Kroll KW, Woolley G, Reeves RK.
europepmc   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

HDFx: A Novel Biologic Immuno Modulator for potential Control and Treatment of NK Cell and Macrophage Dysfunction in Drug-Resistant Tuberculosis [PDF]

, 2017
Burton M. Altura, Bella T. Altura
openalex   +1 more source

Reprogramming CXCL10-mediated NK cell trafficking to enhance immunotherapy in osteosarcoma. [PDF]

Mol Ther Oncol
Jayne WP, Freilich ME, Solanki R, Challagundla KB.   +3 more
europepmc   +1 more source