Results 251 to 260 of about 316,773 (316)

CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity

Advanced Science, EarlyView.
Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung, Alexander Beer, Susmita Ghosh, Ekaterina Pylaeva, Belal Alshaar, Tobias Tertel, Nils Bastian Leimkühler, Thomas Schroeder, Janine Gronewold, Nina Hagemann, Ayan Mohamud Yusuf, Benedikt Frank, Yiqiao Zhang, Dennis Nagel, Kim Schloeßer, Laura Karsch, Emily Hedtfeld, Sabrina Lohmann, Kathrin Blank, Andreas Kraus, Max Krumbein, Nastassia Kabankova, Hongxiao Wang, Almke Bader, Mathis Richter, Fengjun Zhang, Raphael Chevre, Bernd Giebel, Stephan Lang, Anika Grüneboom, Daniela Maier‐Begandt, Anja Hasenberg, Oliver Soehnlein, Hans Christian Reinhardt, Sven Heiles, Jianxu Chen, Jadwiga Jablonska, Albert Sickmann, Dirk M. Hermann, Matthias Gunzer   +39 more
wiley   +1 more source

Mechanotransduction of Piezo1 in the cancer microenvironment: implications for NK cell-based immunotherapy. [PDF]

Front Oncol
Cui X, Zhang B, Zhao J, Tian H.
europepmc   +1 more source

An Integrative Strategy Delineates Modular Metabolic Remodeling and Potential Therapeutic Targets Across Metabolic Diseases

Advanced Science, EarlyView.
An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang, Congxue Hu, Hang Zhao, Xiao Peng, Yiming Yan, Jiasi Wang, Wenqi Jiang, Depeng Mu, Yan Cao, Xia Li, Yunpeng Zhang   +10 more
wiley   +1 more source

Efficacy of intranasal adenovirus vector vaccine is attenuated by type I IFN-induced NK cell activation. [PDF]

Mol Ther Adv
Nakatani H, Tachibana M, Onishi R, Nakagaki T, Ishii KJ, Shimizu K, Sakurai F, Mizuguchi H.   +7 more
europepmc   +1 more source

A multimodal approach integrating NK cell-associated gene signatures and pathomics to predict colon adenocarcinoma prognosis. [PDF]

Sci Rep
Yang K, Lin Q, Zhu J, Zhu T, Fu G.
europepmc   +1 more source

Dysregulated NK-cell gene expression defines the enduring symptoms of long COVID-19. [PDF]

Front Immunol
Ray U, Schulze Selting A, Perera RP, Yang Z, Lysenkov V, Göpel S, Bitzer M, Salker MS, Ossowski S, Riess O, Casadei N, Singh Y.   +11 more
europepmc   +1 more source

Chemotherapy driven alterations in NK cell receptors and ligands in high grade serous ovarian cancer. [PDF]

Front Immunol
Kumar P, Ranmale S, Mehta S, Tongaonkar H, Maniar V, Mania-Pramanik J.   +5 more
europepmc   +1 more source

Constitutive RLI Armoring Enhances CAR-NK Cell Effector Functions but Causes Lethal Toxicity In Vivo. [PDF]

Int J Mol Sci
Ling Z, Wang Y, Wu G, Lin W, Lu T, Yu G, Wang J.   +6 more
europepmc   +1 more source

Accessing invasion-competent Plasmodium vivax merozoites reveals antibody-dependent NK cell activation

Salvador J, Guselli L, Yeat R, Lay S, Thol T, Ya N, Feufack-Donfack L, Heng S, Bohaud C, Orban A, Baldor L, Tat B, Chitnis C, Cantaert T, Popovici J.   +14 more
europepmc   +1 more source