Results 151 to 160 of about 7,960 (193)

Neonatal sevoflurane exposure enhances stress-related neurological susceptibility via NKCC1 modulation. [PDF]

Sci Rep
Yuan BY, Shan LH, Zou J, Xie XH, Gan JQ, Chen BZ.   +5 more
europepmc   +1 more source

Inhibition of NF-κB pathways alleviates hydrocephalus via modulation of choroid plexus epithelium inflammation in a rat intraventricular hemorrhage model. [PDF]

PLoS One
Sun T, Yuan Y, Zhou Y, Wu K, You C, Guan J.   +5 more
europepmc   +1 more source

Zinc, type 2 diabetes, diabetic kidney disease: focus on hypoxia. [PDF]

Front Endocrinol (Lausanne)
Lebedeva SA, Mikhailova EM, Materenchuk MY, Kurkin DV, Samsonov M, Tarasov VV, Mutig K.   +6 more
europepmc   +1 more source

Pharmacological inhibition of SPAK-NKCC1 complex attenuates astrogliosis and restores cerebral blood flow in a mouse model of VCID. [PDF]

Acta Neuropathol Commun
Habib K, Sultan MT, Jahan I, Rahman MS, Kundu SK, Sarker B, Islam R, Ahmed T, Mendez IA, Cao G, Sun D, Tesic V, Bhuiyan MIH.   +12 more
europepmc   +1 more source

Chloride Homeostasis in Neuronal Disorders: Bridging Measurement to Therapy. [PDF]

Life (Basel)
Arosio D, Musio C.
europepmc   +1 more source

Levetiracetam inhibits the Na⁺ HCO₃ ^- transporter Ncbe/NBCn2 (Slc4a10) in the choroid plexus of mice. [PDF]

Acta Physiol (Oxf)
Johnsen LØ, Desdorf LM, Jensen NS, Praetorius J, Damkier HH.   +4 more
europepmc   +1 more source

Efficacy of bumetanide for cognitive improvement in children and adolescents with Down syndrome: study protocol of a randomised, double-blind, placebo-controlled trial. [PDF]

BMJ Open
Costanzo F, Mongiovì VM, Alfieri P, Pontrelli G, Abbate S, De Palma L, Chinali M, Massella L, Scorpecci A, Rocchi F, Fucà E, Averna R, Rava L, Rossetti S, Franco L, Contestabile A, Cancedda L, Vicari S.   +17 more
europepmc   +1 more source

Sleep deprivation impairs information processing via dysregulation of chloride homeostasis in the prefrontal cortex

Frau R, Concas L, Braccagni G, Traccis F, Branca C, Salviati S, Serra V, Corridori E, Nardi G, Pasquini G, Landi S, Santoni M, Follesa P, Brandalise F, Puligheddu M, Melis M, Ratto GM, Scheggi S, Bortolato M.   +18 more
europepmc   +1 more source

CNS pharmacology of NKCC1 inhibitors [PDF]

Neuropharmacology, 2022
The Na-K-2Cl cotransporter NKCC1 and the neuron-specific K-Cl cotransporter KCC2 are considered attractive CNS drug targets because altered neuronal chloride regulation and consequent effects on GABAergic signaling have been implicated in numerous CNS disorders.
Wolfgang Loscher, Kai Kaila
exaly   +6 more sources

Increased NKCC1 expression in refractory human epilepsy

Epilepsy Research, 2007
Cation-chloride co-transporters (CCTs), particularly NKCC1, may be important in epileptogenesis. We have performed a detailed histological examination of NKCC1 in large samples of patients with hippocampal sclerosis (HS) or focal cortical dysplasia (FCD), pathologies both commonly associated with pharmacoresistant epilepsy.
Maria Thom, Matthew C. Walker, Sanjay M Sisodiya   +2 more
exaly   +4 more sources