Results 171 to 180 of about 7,960 (193)

Essential role of NKCC1 in NGF-induced neurite outgrowth

Biochemical and Biophysical Research Communications, 2007
The Na(+)/K(+)/2Cl(-) cotransporter (NKCC) mediates electroneutral transport of 2Cl(-) coupled with Na(+) and K(+) across the plasma membrane, and plays crucial roles in Cl(-) uptake into the cells, homeostasis of cellular Cl(-), and cell volume regulation.
Ken-ichi, Nakajima, Hiroaki, Miyazaki, Naomi, Niisato, Yoshinori, Marunaka   +3 more
openaire   +2 more sources

Synthesis of Bumetanide derivatives and their effects on NKCC1

2020
Das Hauptziel dieser Diplomarbeit war es, Bumetanid (BTN)-Derivate herzustellen. Die neu gewonnenen Derivate sollten die Blut-Hirn-Schranke besser durchdringen als Bumetanid. Es ist bekannt, dass BTN aufgrund seiner Pharmakokinetik die Bluthirnschranke nur zu 1-2% passiert. Bis zu 98% von BTN sind im Plasma gebunden.
openaire   +1 more source

NKCC1 and Brain Maturation

2013
C.K. Pfeffer, C.A. Hübner
openaire   +1 more source

Selective NKCC1 Inhibitors for the Treatment of Neurodevelopmental and Neurological Disorders with Defective NKCC1/KCC2 expression-ratio (P2-12.003)

Neurology, 2023
Annalisa Savardi, Marco Borgogno, Marco De Vivo, Laura Cancedda   +3 more
openaire   +1 more source

Cryo‐EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity

EMBO Journal, 2022
Hans Henrik Gad, Yong Wang, Michael Habeck   +2 more
exaly  

A limited role of NKCC1 in telencephalic glutamatergic neurons for developing hippocampal network dynamics and behavior

Proceedings of the National Academy of Sciences of the United States of America, 2021
Christian A. Hübner, Chuanqiang Zhang, Dirk Isbrandt   +2 more
exaly  

Expression patterns of NKCC1 in neurons and non-neuronal cells during cortico-hippocampal development.

Cerebral Cortex, 2023
exaly  

Molecular mechanism of degradation and turnover of NKCC1

Proceedings of Annual Meeting of the Physiological Society of Japan, 2008
Nakajima, Ken-ichi, Niisato, Naomi, Marunaka, Yoshinori   +2 more
openaire   +1 more source

Rat NKCC2/NKCC1 cotransporter selectivity for loop diuretic drugs

Naunyn-Schmiedeberg's Archives of Pharmacology, 2002
Ricardo P. Garay, C Nazaret, M Alvarez-Guerra   +2 more
exaly  

Sevoflurane-Induced Dysregulation of Cation-Chloride Cotransporters NKCC1 and KCC2 in Neonatal Mouse Brain

Molecular Neurobiology, 2019
Omar Hoseá Cabrera, V Jevtović-Todorović   +1 more
exaly